Search Result
Results for "
Fluorescent analogues
" in MedChemExpress (MCE) Product Catalog:
2
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-118411
-
|
EdU
|
PROTAC Linkers
|
Cancer
|
|
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-D1540
-
|
Cy 5.5 amine; Lumiprobe Cy 5.5 amine
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
-
- HY-D1416
-
HMBR
1 Publications Verification
|
Fluorescent Dye
|
Others
|
|
HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability .
|
-
-
- HY-W039953
-
|
N-azidoacetylglucosamine-tetraacylated
|
Biochemical Assay Reagents
|
Others
|
|
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.
|
-
-
- HY-113870
-
|
|
Fluorescent Dye
|
Others
|
|
6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques .
|
-
-
- HY-120959
-
|
|
Fluorescent Dye
Parasite
|
Others
|
|
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].
|
-
-
- HY-103470
-
|
|
Fluorescent Dye
|
Others
|
|
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM . K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) .
|
-
-
- HY-D1574
-
|
|
Fluorescent Dye
|
Others
|
|
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .
|
-
-
- HY-161681
-
|
|
Guanylate Cyclase
|
Metabolic Disease
|
|
Formycin triphosphate is a fluorescent analogue of ATP which on binding to enzyme active sites exhibits enhanced fluorescence. Formycin triphosphate is an ATP-competitive chicken liver pyruvate carboxylase inhibitor. Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 at about 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 at about 100 μM .
|
-
-
- HY-W003112
-
|
|
Fluorescent Dye
|
Others
|
|
4-Fluororesorcinol is a precursor used in the preparation of fluorescent dyes or indicators such as fluorescein, coumarin and resorcinol analogues .
|
-
-
- HY-D2263
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-cholesterol conjugate-3 (compound 7) is a cholesterol analogue with a fluorescent BODIPY group. BODIPY-cholesterol conjugate-3 can be used to simultaneously visualize multiple cholesterol pools in cells, as it is primarily localized to the plasma membrane .
|
-
-
- HY-161164
-
|
|
DNA Stain
|
Others
|
|
Tricyclic cytosine tC is a fluorescent base analogue that can be used as a fluorescent probe in nucleic acid-containing systems. The excitation wavelength is 385 nm and the emission wavelength is 505 nm .
|
-
-
- HY-D1340
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
-
- HY-141575
-
|
|
Fluorescent Dye
|
Others
|
|
C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .
|
-
-
- HY-D1119A
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester tripotassium is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
-
- HY-134308
-
|
|
Fluorescent Dye
|
Others
|
|
8-NBD-cAMP sodium is a fluorescently labeled cyclic adenosine phosphate (cAMP) analogue. 8-NBD-cAMP sodium retains a similar biological activity to cAMP, regulating their activity by binding to specific proteins such as EPACs or PKA. 8-NBD-cAMP sodium can be used in fluorescent competitive binding experiments to evaluate the binding affinity of newly synthesized EPAC1 agonists to EPAC1 proteins .
|
-
-
- HY-173538
-
|
NBD SM(d18:1/6:0)
|
Fluorescent Dye
|
Others
|
|
C6 NBD Sphingomyelin (d18:1/6:0) (NBD SM(d18:1/6:0)) is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). C6 NBD Sphingomyelin (d18:1/6:0) has neutral sphingomyelinase (N-SMase) activity .
|
-
-
- HY-135637
-
|
|
Fluorescent Dye
|
Others
|
|
Nilotinib Acid, an analogue of Nilotinib, is usually used as a labeled chemical or fluorescent probe.
|
-
-
- HY-D1582
-
|
|
Fluorescent Dye
|
Others
|
|
C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .
|
-
-
- HY-135634
-
|
|
Fluorescent Dye
|
Others
|
|
GNF-2-PEG-acid, an analogue of GNF-2, is usually used as a labeled chemical or fluorescent probe.
|
-
-
- HY-135635
-
|
|
Fluorescent Dye
|
Others
|
|
ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.
|
-
-
- HY-134311
-
|
|
Fluorescent Dye
|
Others
|
|
8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites
|
-
-
- HY-129097
-
|
|
Fluorescent Dye
|
Others
|
|
FFN-102 trifluoroacetate is an analogue of biogenic neurotransmitters. FFN-102 trifluoroacetate is a pH-dependent fluorescent probe that labels dopamine cell bodies, axons, and presynaptic terminals .
|
-
-
- HY-D1398
-
|
|
nAChR
|
Neurological Disease
|
|
LtIA-F, a novel fluorescent analogue of LtIA, provides a wealth of pharmacological tools to explore the structure–function relationship, distribution, and ligand binding domain of the α3β2 nAChR subtype.
|
-
-
- HY-137592A
-
|
ε-NAD sodium
|
Fluorescent Dye
|
Others
|
|
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) sodium, a fluorescent analogue of NAD, is able to serve as a substrate for the bacterial toxincatalyzed G-ADP ribosylation of signal-transducing G-proteins. Nicotinamide 1,N6-ethenoadenine dinucleotide sodium can be used as a fluorescent substrate for the studies of the ADP ribosylation reaction .
|
-
-
- HY-135636
-
|
|
Fluorescent Dye
|
Others
|
|
Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe. Ponatinib Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-131772
-
|
|
Fluorescent Dye
|
Others
|
|
2-AHA-cAMP is an analogue of natural signal molecule cAMP and an activator of cAMP-dependent protein kinase. 2-AHA-cAMP has a free terminal primary amino group, which can be used for coupling to gels or fluorescent dyes .
|
-
-
- HY-173530
-
|
8-Bromo TNP-Guanosine 5'-triphosphate tetrasodium
|
Fluorescent Dye
|
Others
|
|
8-Bromo TNP-GTP (8-Bromo TNP-Guanosine 5'-triphosphate) tetrasodium is a fluorescent TNP-GTP analogue with a TNP fluorophore and a bromo group at the 8-position. 8-Bromo TNP-GTP tetrasodium can be used to analyze the binding activity of GTP-binding proteins (such as Ras and Gα subunits) .
|
-
-
- HY-147114
-
|
|
Fluorescent Dye
|
Others
|
|
3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a DNA uptake tracer, a pteridine-based fluorescent guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm .
|
-
-
- HY-D1119B
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
-
- HY-156020
-
|
|
Glycosidase
|
Metabolic Disease
|
|
Glucocerebrosidase-IN-2 (compound 12) is a quinazoline analogue and an inhibitor of glucocerebrosidase (GC). Glucocerebrosidase-IN-2 has the potential to improve GC translocation to lysosomes in Gaucher disease patient-derived cells (mostly carrying the N370S mutation). Glucocerebrosidase-IN-2 inhibits the hydrolysis of 4-methylumbelliferone β-D-glucopyranoside (4MU) and fluorescent glycosylceramide (FlourGC) in N370S mutant tissues with an AC50 of 25.29 μM .
|
-
-
- HY-N15885
-
|
|
Fluorescent Dye
FABP
Phosphatase
|
Metabolic Disease
|
|
12-NBD Stearate is a fluorescent fatty acid analogue. 12-NBD Stearate binds to fatty acid binding protein (FABP) and sterol carrier protein-2 (SCP-2). Overexpressing sterol carrier protein-2 (SCP-2) 15-kDa isoform enhances 12-NBD Stearate transport. 12-NBD Stearate is a tool for microscopic long chain fatty acids (LCFA) uptake and internalization studies .
|
-
-
- HY-118411S
-
|
EdU-13C
|
Isotope-Labeled Compounds
PROTAC Linkers
|
Cancer
|
|
5-Ethynyl-2'-deoxyuridine- 13C1 (EdU- 13C1) is the 13C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-134392A
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
6-Alkyne-NAD+ sodium is a nicotinamide adenine dinucleotide (NAD) analogue. 6-Alkyne-NAD+ sodium can be used as a fluorescent probe coupled with fluorescent labels for marking ADP-ribose polymerase substrate proteins .
|
-
-
- HY-175055
-
|
C12 NBD phytosphingosine (t18:0/12:0); NBD cer (t18:0/12:0); NBD ceramide (t18:0/12:0)
|
Fluorescent Dye
Drug Derivative
|
Others
|
|
C12 NBD Phytoceramide (t18:0/12:0) is a ceramide analogue composed of a phytoceramide and green fluorescent C12 NBD. C12 NBD Phytoceramide (t18:0/12:0) is a fluorescent substrate (Ex=485 nM, Em=525 nM) and can be used to detect ceramidase (such as diacylglycerol acyltransfereases Lro1p) activity .
|
-
-
- HY-175119
-
|
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
3'-Bromo ANT-dATP sodium is a fluorescent ribosyl-modified analogue of the purine nucleotide dATP. The maximum excitation/emission wavelengths of 3'-Bromo ANT-dATP sodium in water are approximately 345/425 nm. 3'-Bromo ANT-dATP sodium can be used as a substrate for various enzymes in molecular biology research.
|
-
-
- HY-137744
-
|
|
Adenylate Cyclase
Nucleoside Antimetabolite/Analog
|
Infection
|
|
MANT-GppNHp is a competitive adenyl cyclase (AC) inhibitor. MANT-GppNHp is a fluorescently labeled GTP (HY-113225) analogue. MANT-GppNHp interacts with the hydrophobic pocket near the AC catalytic site through its MANT group, thereby directly blocking the binding of the substrate ATP. MANT-GppNHp can be used to study diseases related to the increased activity of AC (such as cholera) .
|
-
-
- HY-175080
-
|
|
Drug Derivative
Fluorescent Dye
|
Others
|
|
8-DY547-cGMP is a fluorescent cGMP analogue composed of a dye DY547 to position 8 of cGMP. 8-DY547-cGMP is a Cyclic nucleotide-gated A2 (CNGA2) ligand. 8-DY547-cGMP can activated CNGA2 channel. 8-DY547-cGMP can be used for simultaneously detection CNG channel activation and ligand binding .
|
-
-
- HY-118411S1
-
|
EdU-13C2
|
Isotope-Labeled Compounds
PROTAC Linkers
|
Cancer
|
|
5-Ethynyl-2'-deoxyuridine- 13C2 (EdU- 13C2) is the 13C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D1540
-
|
Cy 5.5 amine; Lumiprobe Cy 5.5 amine
|
Fluorescent Dyes
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
- HY-D1416
-
HMBR
1 Publications Verification
|
Fluorescent Dyes
|
|
HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525–539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability .
|
-
- HY-113870
-
|
|
Fluorescent Dyes
|
|
6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques .
|
-
- HY-120959
-
|
|
Fluorescent Dyes
|
|
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].
|
-
- HY-103470
-
|
|
Fluorescent Dyes
|
|
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM . K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) .
|
-
- HY-D1574
-
|
|
Fluorescent Dyes
|
|
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .
|
-
- HY-D2263
-
|
|
Fluorescent Dyes
|
|
BODIPY-cholesterol conjugate-3 (compound 7) is a cholesterol analogue with a fluorescent BODIPY group. BODIPY-cholesterol conjugate-3 can be used to simultaneously visualize multiple cholesterol pools in cells, as it is primarily localized to the plasma membrane .
|
-
- HY-D1340
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
- HY-141575
-
|
|
Fluorescent Dyes
|
|
C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .
|
-
- HY-D1119A
-
|
|
Fluorescent Dyes
|
|
AF647-NHS ester tripotassium is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
- HY-135637
-
|
|
Fluorescent Dyes
|
|
Nilotinib Acid, an analogue of Nilotinib, is usually used as a labeled chemical or fluorescent probe.
|
-
- HY-D1582
-
|
|
Fluorescent Dyes
|
|
C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .
|
-
- HY-135634
-
|
|
Fluorescent Dyes
|
|
GNF-2-PEG-acid, an analogue of GNF-2, is usually used as a labeled chemical or fluorescent probe.
|
-
- HY-135635
-
|
|
Fluorescent Dyes
|
|
ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.
|
-
- HY-135636
-
|
|
Fluorescent Dyes
|
|
Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe. Ponatinib Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147114
-
|
|
Fluorescent Dyes
|
|
3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a DNA uptake tracer, a pteridine-based fluorescent guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm .
|
-
- HY-D1119B
-
|
|
Fluorescent Dyes
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N15885
-
|
|
Lipid
|
Fluorescent Dye
FABP
Phosphatase
|
|
12-NBD Stearate is a fluorescent fatty acid analogue. 12-NBD Stearate binds to fatty acid binding protein (FABP) and sterol carrier protein-2 (SCP-2). Overexpressing sterol carrier protein-2 (SCP-2) 15-kDa isoform enhances 12-NBD Stearate transport. 12-NBD Stearate is a tool for microscopic long chain fatty acids (LCFA) uptake and internalization studies .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-118411S
-
|
|
|
5-Ethynyl-2'-deoxyuridine- 13C1 (EdU- 13C1) is the 13C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-118411S1
-
|
|
|
5-Ethynyl-2'-deoxyuridine- 13C2 (EdU- 13C2) is the 13C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-118411
-
|
EdU
|
|
PROTAC Synthesis
Alkynes
|
|
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W039953
-
|
N-azidoacetylglucosamine-tetraacylated
|
|
Azide
|
|
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.
|
-
- HY-118411S
-
|
EdU-13C
|
|
Alkynes
|
|
5-Ethynyl-2'-deoxyuridine- 13C1 (EdU- 13C1) is the 13C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-118411S1
-
|
EdU-13C2
|
|
Alkynes
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5-Ethynyl-2'-deoxyuridine- 13C2 (EdU- 13C2) is the 13C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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