MANT-GppNHp
MANT-GppNHp is a competitive adenyl cyclase (AC) inhibitor. MANT-GppNHp is a fluorescently labeled GTP (HY-113225) analogue. MANT-GppNHp interacts with the hydrophobic pocket near the AC catalytic site through its MANT group, thereby directly blocking the binding of the substrate ATP. MANT-GppNHp can be used to study diseases related to the increased activity of AC (such as cholera).
For research use only. We do not sell to patients.
- CAS No.: 148821-01-6
- Formula: C18H24N7O14P3
- Molecular Weight:655.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 148821-01-6
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Molecular Weight 655.35
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Formula C18H24N7O14P3
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SMILES
O[C@@H]1[C@H](OC(C2=C(NC)C=CC=C2)=O)[C@@H](CO[P](O[P](N[P](O)(O)=O)(O)=O)(O)=O)O[C@H]1N3C(NC(N)=NC4=O)=C4N=C3.O=C5C6=C(NC(N)=N5)N([C@H]7[C@H](OC(C8=C(NC)C=CC=C8)=O)[C@H](O)[C@@H](CO[P](O[P](N[P](O)(O)=O)(O)=O)(O)=O)O7)C=N6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)