4-Fluororesorcinol
Based on 1 Customer Validation
4‑Fluororesorcinol is a class of fluorinated resorcinol aromatic small molecules that participates in fluorescence-generating chemical reactions under alkaline conditions. 4‑Fluororesorcinol undergoes a fluorescence-generating reaction with dopamine in an alkaline aqueous solution system to produce an azacyclooctane derivative that emits blue fluorescence. 4‑Fluororesorcinol serves as a building block for fluorescent dyes.
For research use only. We do not sell to patients.
- Purity: 99.13%
- CAS No.: 103068-41-3
- Formula: C6H5FO2
- Molecular Weight:128.10
-
Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
HY-108298
Perfluorodecalin
-
HY-109540
Perfluorohexane
-
HY-21190
Perfluorobutylsulfonyl fluoride
-
HY-W015753
3-Fluorobenzoic acid
-
HY-Y0680
3-Chloro-4-fluoroaniline
-
HY-W007410
2,4-Difluorobenzaldehyde
-
HY-W002068
2,4-Difluorobenzoic acid
-
HY-W008598
2-Bromo-4'-fluoroacetophenone
-
HY-Y0357
2-Fluorophenylacetic acid
-
HY-W015477
2-Chloro-6-fluorobenzaldehyde
-
HY-Y1747
4-Bromo-2,6-difluorobenzaldehyde
-
HY-108298R
Perfluorodecalin (Standard)
Biological Activity
4-Fluororesorcinol can be synthesized from 5-nitro-1,2,4-trifluorobenzene via four consecutive reactions; it reacts with phthalic anhydride in methanesulfonic acid to form 2′,7′-difluorofluorescein; it reacts with trimellitic anhydride in methanesulfonic acid to form 5 (6)-carboxy-2′,7′-difluorofluorescein; and it reacts with tetrafluorophthalic anhydride in methanesulfonic acid to form 2′,4,5,6,7,7′-hexafluorofluorescein[1].
4‑Fluororesorcinol reacts with dopamine to produce a blue fluorescent product (excitation wavelength 416 nm, emission wavelength 461 nm); the fluorescence intensity of the product reaches its maximum when the concentration of 4‑Fluororesorcinol is 150 µM with incubation for 30 min. Under this condition, a fluorescent probe can be constructed to achieve selective "turn-off" detection of tetracycline[2].
4-Fluororesorcinol efficiently generates the triarylmethane precursor of 4-Carboxy-pennsylvania green (HY-D1205), which can be converted into the target fluorophore via cyclization and hydrolysis[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 103068-41-3
-
Appearance Solid
-
Molecular Weight 128.10
-
Formula C6H5FO2
-
Color Light yellow to brown
-
SMILES
FC1=C(O)C=C(O)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 200 mg/mL (1561.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8064 mL | 39.0320 mL | 78.0640 mL | 195.1600 mL |
| 5 mM | 1.5613 mL | 7.8064 mL | 15.6128 mL | 39.0320 mL | |
| 10 mM | 0.7806 mL | 3.9032 mL | 7.8064 mL | 19.5160 mL | |
| 15 mM | 0.5204 mL | 2.6021 mL | 5.2043 mL | 13.0107 mL | |
| 20 mM | 0.3903 mL | 1.9516 mL | 3.9032 mL | 9.7580 mL | |
| 25 mM | 0.3123 mL | 1.5613 mL | 3.1226 mL | 7.8064 mL | |
| 30 mM | 0.2602 mL | 1.3011 mL | 2.6021 mL | 6.5053 mL | |
| 40 mM | 0.1952 mL | 0.9758 mL | 1.9516 mL | 4.8790 mL | |
| 50 mM | 0.1561 mL | 0.7806 mL | 1.5613 mL | 3.9032 mL | |
| 60 mM | 0.1301 mL | 0.6505 mL | 1.3011 mL | 3.2527 mL | |
| 80 mM | 0.0976 mL | 0.4879 mL | 0.9758 mL | 2.4395 mL | |
| 100 mM | 0.0781 mL | 0.3903 mL | 0.7806 mL | 1.9516 mL |
4-Fluororesorcinol Related Classifications
HY-W003112 Related Classifications
Powered by Bioz
- 4-Fluororesorcinol
- 103068-41-3
- Drug Intermediate
- 2′,7′-difluorofluorescein
- aquatic environments
- 2′,4,5,6,7,7′-hexafluorofluorescein
- dopamine
- 4-carboxy-Pennsylvania Green
- tetracycline
- Pennsylvania Green
- fluorinated fluoresceins
- triarylmethane precursor
- 5(6)-carboxy-2′,7′-difluorofluorescein
- Inhibitor
- inhibitor
- inhibit