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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
Krebs cycle
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "Krebs cycle" in MCE Product Catalog:
6
6 Publications Verification
Cat. No.: HY-W013636
CAS No.: 328-50-7
Synonyms: Alpha-Ketoglutaric acid; 2-Oxoglutaric acid
Category:
Anti-aging Endocrine diseases Endogenous metabolite Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Disease Research Fields
Target:
6
6 Publications Verification
Cat. No.: HY-W013636A
CAS No.: 22202-68-2
Synonyms: Alpha-Ketoglutaric acid Sodium
Target:
6
6 Publications Verification
Cat. No.: HY-W013636B
CAS No.: 71686-01-6
Target:
6
6 Publications Verification
Cat. No.: HY-W013636C
CAS No.: 997-43-3
Synonyms: Alpha-Ketoglutaric acid potassium
Cat. No.: HY-W013636S
CAS No.: 161096-83-9
Synonyms: Alpha-Ketoglutaric acid-13C5
Cat. No.: HY-163771
CAS No.: 3047101-14-1
Target:
Research Areas:
Pyruvate Carboxylase-IN-5 (compound 6m) is a pyruvate carboxylase inhibitor with high selectivity and permeability. Pyruvate carboxylase is a mitochondrial enzyme that catalyzes the carboxylation of pyruvate to oxaloacetate, a process that plays an important role in maintaining steady-state levels of Krebs cycle intermediates, which are precursors for the synthesis of biomacromolecules such as amino acids, fatty acids, and glucose .
Cat. No.: HY-W016813
CAS No.: 4023-65-8
Category:
Human Gut Microbiota Metabolites Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer
Target:
Cat. No.: HY-W013636S1
CAS No.: 1381759-60-9
Synonyms: Alpha-Ketoglutaric acid-d4
Target:
Research Areas:
Pyruvate carboxylase is a key mitochondrial anaplerotic enzyme that catalyzes the conversion of pyruvate to oxaloacetate. Pyruvate carboxylase not only maintains tricarboxylic acid cycle activity and redox homeostasis, but also drives hepatic gluconeogenesis and fatty acid synthesis. The activity of Pyruvate carboxylase is upregulated in insulin-resistant states, exacerbating hepatic glucose production. Pyruvate carboxylase also shows significantly enhanced expression in early-stage non-small cell lung cancer (NSCLC). Pyruvate carboxylase promotes tumor proliferation by supporting nucleotide and lipid synthesis, and its functional deficiency cannot be compensated by glutaminolysis. Pyruvate carboxylase can be used in the research of prediabetes type 2 and NSCLC .
Cat. No.: HY-W250310
CAS No.: 16856-18-1
Synonyms: L-Arginine alpha-ketoglutarate
Cat. No.: HY-W013636S2
CAS No.: 1173021-86-7
Synonyms: Alpha-Ketoglutaric acid-d6
Cat. No.: HY-W013636R
CAS No.: 328-50-7
Synonyms: Alpha-Ketoglutaric acid (Standard); 2-Oxoglutaric acid (Standard)
Cat. No.: HY-W013636S3
CAS No.: 108395-15-9
Synonyms: Alpha-Ketoglutaric acid-13C
Cat. No.: HY-168943
Cat. No.: HY-44134R
CAS No.: 13192-04-6
Synonyms: Dimethyl α-ketoglutarate (Standard)
Category:
Cat. No.: HY-W013636S4
CAS No.: 123953-28-6
Synonyms: Alpha-Ketoglutaric acid-13C2
Cat. No.: HY-W013636AR
CAS No.: 22202-68-2
Synonyms: Alpha-Ketoglutaric acid Sodium (Standard)
Cat. No.: HY-W013636AG
CAS No.: 22202-68-2
Synonyms: Alpha-Ketoglutaric acid Sodium (GMP)
Cat. No.: HY-P2994B
Target:
Research Areas:
3-Hydroxybutyrate Dehydrogenase, Alcaligenes faecalis (EC 1.1.1.30) catalyzes the oxidation of 3-hydroxybutyrate to acetoacetate, the first step in the conversion of ketone bodies to citric acid, which is then further metabolized via the tricarboxylic acid cycle (Krebs cycle).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
