2. Metabolic Enzyme/Protease
  3. Tyrosinase Endogenous Metabolite
  4. 2-Ketoglutaric acid Sodium

2-Ketoglutaric acid Sodium  (Synonyms: Alpha-Ketoglutaric acid Sodium)

Cat. No.: HY-W013636A
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2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM).

For research use only. We do not sell to patients.

2-Ketoglutaric acid Sodium Chemical Structure

2-Ketoglutaric acid Sodium Chemical Structure

CAS No. : 22202-68-2

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Based on 2 publication(s) in Google Scholar

Other Forms of 2-Ketoglutaric acid Sodium:

2-Ketoglutaric acid Sodium Related Antibodies

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Description

2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM)[1][2].

IC50 & Target[1]

Human Endogenous Metabolite

 

Microbial Metabolite

 

Tyrosinase

15 mM (IC50)

In Vitro

2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning[1].
2-Ketoglutaric acid Sodium acts as precursor for the synthesis of amino acids and nucleotides[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Ketoglutaric acid Sodium Related Antibodies
Molecular Weight

168.08

Formula

C5H5NaO5
CAS No.
SMILES

O=C(O[Na])C(CCC(O)=O)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2-Ketoglutaric acid Sodium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Ketoglutaric acid22202-68-2Alpha-Ketoglutaric acidTyrosinaseEndogenous MetaboliteintermediateprecursorTCAcarbonskeletonInhibitorinhibitorinhibit

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