1. Metabolic Enzyme/Protease
  2. Tyrosinase
    Endogenous Metabolite
  3. Calcium 2-oxoglutarate

Calcium 2-oxoglutarate 

Cat. No.: HY-W013636B
Handling Instructions

Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM).

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Calcium 2-oxoglutarate Chemical Structure

Calcium 2-oxoglutarate Chemical Structure

CAS No. : 71686-01-6

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Description

Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM)[1][2].

IC50 & Target[1]

Tyrosinase

15 mM (IC50)

Human Endogenous Metabolite

 

In Vitro

Calcium 2-oxoglutarate has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning[1].
Calcium 2-oxoglutarate acts as precursor for the synthesis of amino acids and nucleotides[2].

Molecular Weight

184.16

Formula

C₅H₄CaO₅

CAS No.

71686-01-6

SMILES

O=C([O-])C(CCC([O-])=O)=O.[Ca+2]

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Calcium 2-oxoglutarateTyrosinaseEndogenous MetaboliteintermediateprecursorTCAcarbonskeletonInhibitorinhibitorinhibit

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Calcium 2-oxoglutarate
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HY-W013636B
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