1. Metabolic Enzyme/Protease
  2. Tyrosinase
    Endogenous Metabolite
  3. Calcium 2-oxoglutarate

Calcium 2-oxoglutarate 

Cat. No.: HY-W013636B
Handling Instructions

2-Ketoglutaric acid calcium (Alpha-Ketoglutaric acid calcium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid calcium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid calcium is a reversible inhibitor of tyrosinase (IC50=15 mM).

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Calcium 2-oxoglutarate Chemical Structure

Calcium 2-oxoglutarate Chemical Structure

CAS No. : 71686-01-6

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Description

2-Ketoglutaric acid calcium (Alpha-Ketoglutaric acid calcium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid calcium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid calcium is a reversible inhibitor of tyrosinase (IC50=15 mM)[1][2].

IC50 & Target[1]

Tyrosinase

15 mM (IC50)

Human Endogenous Metabolite

 

In Vitro

2-Ketoglutaric acid calcium (Alpha-Ketoglutaric acid calcium) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning[1].
2-Ketoglutaric acid calcium acts as precursor for the synthesis of amino acids and nucleotides[2].

Molecular Weight

184.16

Formula

C₅H₄CaO₅

CAS No.

71686-01-6

SMILES

O=C([O-])C(CCC([O-])=O)=O.[Ca+2]

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Calcium 2-oxoglutarateTyrosinaseEndogenous MetaboliteintermediateprecursorTCAcarbonskeletonInhibitorinhibitorinhibit

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Calcium 2-oxoglutarate
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HY-W013636B
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