Mucin MUC1

By Targets:	Mucin (6) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (1) Endogenous Metabolite (1) Topoisomerase (1) Transmembrane Glycoprotein (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (7)
Oligonucleotides:	Aptamers (1)

Targets Recommended: Mucin Tim3

Cat. No.	Nom du produit	Target	Áreas de investigación	Chemical Structure

HY-P99634

Gatipotuzumab PankoMab; DS-3939a antibody	Mucin	Cancer
Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) .

HY-177442

DS-3939a DS-3939	Antibody-Drug Conjugates (ADCs) Mucin Topoisomerase Apoptosis	Cancer
DS-3939a (DS-3939) is an anti-TA-MUC1 *(tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1* IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .

HY-P2508

MUC1, mucin core	Mucin	Cancer
MUC1, mucin core is the region of the MUC1 mucin core. MUC1 is a type I transmembrane glycoprotein, and is overexpressed and aberrantly glycosylated in carcinoma cells. MUC1, mucin core protein binds to domain 1 of ICAM-1 .

HY-P99968

Clivatuzumab	Mucin	Cancer
Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers .

HY-E70290

N-Acetylgalactosaminyltransferase 1 GALNT1	Endogenous Metabolite β-catenin Wnt	Cancer
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer can promote abnormal O-glycosylation of CD44, thereby activating the Wnt/β-catenin signaling pathway and regulating the malignant behavior of gastric cancer cells. Additionally, N-Acetylgalactosaminyltransferase 1 plays a crucial role in cancer growth and metastasis by modifying the O-glycosylation of various glycoproteins, such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3 .

HY-160060

MA3 aptamer sodium	Mucin	Cancer
MA3 aptamer sodium is an 86-base long DNA aptamer targeting the mucin MUC1. MA3 aptamer sodium binds to the peptide epitope of mucin 1 (MUC1) with a Kd of 38.3 nM and has minimal cross-reactivity with albumin .

HY-P5472

Tumour-associated MUC1 epitope	Transmembrane Glycoprotein	Others
Tumour-associated MUC1 epitope is a biological active peptide. (This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide. It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies.)

HY-P992131

Sacomitatug	Mucin	Cancer
Sacomitatug is a humanized IgG1-κ monoclonal antibody targeting mucin 1 (MUC1). Sacomitatug exerts anti-tumor effects by blocking MUC1-mediated tumor proliferation signals and activating immune effectors .

Cat. No.	Nom du produit	Type

HY-177442

DS-3939a DS-3939	Fluorescent Dyes
DS-3939a (DS-3939) is an anti-TA-MUC1 *(tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1* IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .

DS-3939a

DS-3939

Fluorescent Dyes

DS-3939a (DS-3939) is an anti-TA-MUC1 (tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1 IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .

Cat. No.	Nom du produit	Target	Research Area

HY-P2508

MUC1, mucin core	Mucin	Cancer
MUC1, mucin core is the region of the MUC1 mucin core. MUC1 is a type I transmembrane glycoprotein, and is overexpressed and aberrantly glycosylated in carcinoma cells. MUC1, mucin core protein binds to domain 1 of ICAM-1 .

HY-P5472

Tumour-associated MUC1 epitope	Transmembrane Glycoprotein	Others
Tumour-associated MUC1 epitope is a biological active peptide. (This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide. It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies.)

Cat. No.	Nom du produit	Target	Research Area	Image

HY-P99634

Gatipotuzumab PankoMab; DS-3939a antibody	Mucin	Cancer
Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) .

HY-P99968

Clivatuzumab	Mucin	Cancer
Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers .

HY-P992131

Sacomitatug	Mucin	Cancer
Sacomitatug is a humanized IgG1-κ monoclonal antibody targeting mucin 1 (MUC1). Sacomitatug exerts anti-tumor effects by blocking MUC1-mediated tumor proliferation signals and activating immune effectors .

Species:	Human (12) Mouse (1) Cynomolgus (1)
Tag:	His (5) Tag Free (1) Avi (2) Fc (8)
Source:	HEK293 (13) E. coli (1)

Cat. No.	Compare	Nom du produit	Species	Source	Image

HY-P78774

	Mucin-1/MUC1 Protein, Human (HEK293, mFc) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (HEK293, mFc) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P78833

	Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, His-Avi) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78578

	Mucin-15/MUC15 Protein, Cynomolgus (HEK293, Fc) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Cynomolgus	HEK293
	MUC15 is a membrane-bound mucin. The human MUC15 protein contains an extracelluar domain, a small transmembrane domain, and a highly conserved cytoplasmic tail. MUC15 overexpression suppresses trophoblast-like cell invasion. Mucin-15/MUC15 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived Mucin-15/MUC15 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78733

	Mucin-1/MUC1 Protein, Human (269a.a, HEK293, His) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (269a.a, HEK293, His) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78734

	Mucin-1/MUC1 Protein, Human (120a.a, HEK293, His) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (120a.a, HEK293, His) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78740

	Mucin-1/MUC1 Protein, Human (357a.a, HEK293, Fc) MUCin 1; MUC1; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; SEC; MUC-1; X; MUC1; ZD; PEM; PEMT; PUM; CA15-3; Episialin	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (357a.a, HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704797

	Mucin-1/MUC1 Isoform Z Protein, Human (Fc) MUC1/Z; MUC1; MUC-1; MUCin-1; MUCin1; CA 15-3; Episialin; H23AG; KL-6; PEMT; PUM; PEM; EMA; CD227;	Human	E. coli
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Isoform Z Protein, Human (Fc) is the recombinant human-derived Mucin-1/MUC1 Isoform Z protein, expressed by E. coli, with C-hFc labeled tag.

HY-P700795

	Mucin-1/MUC1 Isoform Y Protein, Human (HEK293, Fc) MUC1/Y; MUC1; MUC-1; MUCin-1; MUCin1; CA 15-3; Episialin; H23AG; KL-6; PEMT; PUM; PEM; EMA; CD227;	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Isoform Y Protein, Human (HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 Isoform Y protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704796

	Mucin-1/MUC1 Isoform Z Protein, Human (HEK293, Fc) MUC1/Z; MUC1; MUC-1; MUCin-1; MUCin1; CA 15-3; Episialin; H23AG; KL-6; PEMT; PUM; PEM; EMA; CD227;	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Isoform Z Protein, Human (HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 Isoform Z protein, expressed by HEK293, with C-hFc labeled tag.

HY-P704798

	Mucin-1/MUC1 Protein, Human (357a.a, HEK293, His) MUC1/Y; MUC1; MUC-1; MUCin-1; MUCin1; CA 15-3; Episialin; H23AG; KL-6; PEMT; PUM; PEM; EMA; CD227;	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (357a.a, HEK293, His) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293, with C-His labeled tag.

HY-P73802

	Mucin-1/MUC1 Protein, Human (HEK293) MUCin-1; MUC-1; Episialin; CD227; MUC1-alpha	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (HEK293) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with tag free.

HY-P72399

	Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, Fc-Avi) MUC-1; CA 15-3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; PUM; PEM; EMA; CD227; MUC1	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

HY-P70301

	Mucin-1/MUC1 Protein, Human (HEK293, Fc) rHuMUCin-1, Fc; MUCin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary MUCin; PUM; Polymorphic epithelial MUCin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated MUCin; CD227; MUC1	Human	HEK293
	Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. At the same time, the β subunit and its C-terminal domain participate in cell signaling through phosphorylation and protein-protein interactions. Mucin-1/MUC1 Protein, Human (HEK293, Fc) is the recombinant human-derived Mucin-1/MUC1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704178

	Mucin-1/MUC1 Protein, Mouse (HEK293, His) rHuMUCin-1, Fc; MUCin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary MUCin; PUM; Polymorphic epithelial MUCin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated MUCin; CD227; MUC1	Mouse	HEK293
	Mucin-1/MUC1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Mucin-1/MUC1 protein, expressed by HEK293, with C-His tag.

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Host:	Mouse (4) Rabbit (2)
Reactivity:	Human (6)
Application:	IHC-P (6) ICC/IF (3) IP (1) WB (2) FC (3) ELISA (5)
Isotype:	IgG (2) IgG1 (4)
Conjugation:	Non-conjugated (6) Biotin (2)
Clonality:	Polyclonal (1) Monoclonal (4) Recombinant (1)
Modification:	Unmodified (5)

Cat. No.	Compare	Nom du produit	Application	Reactivity	Image

HY-P84120

	Mucin 1 Antibody (YA3817) MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC	IHC-P, FC, ELISA	Human
	Mucin 1 Antibody (YA3817) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 1.

HY-P84120A

	Mucin 1 Antibody (YA3817)(PBS only) MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC	IHC-P, FC, ELISA	Human
	Mucin 1 Antibody (YA3817) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 1.

HY-P84932

	Mucin 1 Antibody MUC1; PUM; MUCin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary MUCin; PUM; Polymorphic epithelial MUCin; PEM; Tumor-associated ep	IHC-P, ICC/IF, ELISA	Human
	Mucin 1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Mucin 1.

HY-P83341

	Mucin 1 Antibody (YA3086) MUC1; PUM; MUCin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary MUCin; PUM; Polymorphic epithelial MUCin; PEM; Tumor-associated ep	WB, IHC-P, ICC/IF, IP, FC	Human
	Mucin 1 Antibody (YA3086) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mucin 1.

HY-P85834

	Mucin 1 Antibody (YA5526) ADMCKD; ADMCKD1; Breast carcinoma associated antigen DF3; Breast carcinoma-associated antigen DF3; CA 15-3; CA15 3; CA15 3 antigen; CA15-3; CA15.3; Cancer antigen 15-3; Carcinoma associated MUCin; Carcinoma-associated MUCin; CD 227; CD227; DF3 antigen; EMA; Episialin; Epithelial Membrane Antigen; H23 antigen; H23AG; KL 6; KL-6; KL6; Krebs von den Lungen-6; MAM 6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease 1; autosomal dominant; Medullary cystic kidney disease, autosomal dominant; MUC 1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; MUC1_HUMAN; MUCin 1; MUCin 1 cell surface associated; MUCin 1 transmembrane; MUCin 1, cell surface associated; MUCin-1 subunit beta; Peanut reactive urinary MUCin; Peanut-reactive urinary MUCin; PEM; PEMT; Polymorphic epithelial MUCin; PUM; Tumor associated epithelial membrane antigen; Tumor associated epithelial MUCin; Tumor associated MUCin; Tumor-associated epithelial membrane antigen; Tumor-associated MUCin	IHC-P, WB, ICC/IF, ELISA	Human
	Mucin 1 Antibody (YA5526) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 1.

HY-P86024

	Mucin 1 Antibody (YA5716) MUCin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated MUCin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary MUCin; PUM; Polymorphic epithelial MUCin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated MUCin; CD antigen CD227; [Cleaved into: MUCin-1 subunit alpha; MUC1-NT; MUC1-alpha; MUCin-1 subunit beta; MUC1-beta; MUC1-CT; ]	IHC-P, ELISA	Human
	Mucin 1 Antibody (YA5716) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 1.

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Cat. No.	Nom du produit		Classification

HY-160060

MA3 aptamer sodium		Aptamers
MA3 aptamer sodium is an 86-base long DNA aptamer targeting the mucin MUC1. MA3 aptamer sodium binds to the peptide epitope of mucin 1 (MUC1) with a Kd of 38.3 nM and has minimal cross-reactivity with albumin .

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Inhibitors & Agonists

Fluorescent Dyes

Peptides

Inhibitory Antibodies

Protéines recombinantes

Antibodies

Oligonucleotides