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Results for "

OTU

" in MedChemExpress (MCE) Product Catalog:

8

Recombinant Proteins

8

Antibodies

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Cat. No. Compare Product Name Species Source Image
  • HY-P701482
    OTUD2 Protein, Human

    YOD1; Ubiquitin thioesterase OTU1; DUBA-8; HIV-1-induced protease 7; HIN-7; HsHIN7; OTU domain-containing protein 2

    		 Human E. coli
    OTUD2 is a key hydrolase in cellular processes that actively participates in endoplasmic reticulum-associated degradation (ERAD) by deubiquitinating misfolded luminal proteins. It trims ubiquitin chains from the substrate, helping them pass through the VCP/p97 pore. OTUD2 Protein, Human is the recombinant human-derived OTUD2 protein, expressed by E. coli , with tag free.
  • HY-P701484
    OTUD6A Protein, Human

    OTUD6A; OTU domain-containing protein 6A; DUBA-2

    		 Human E. coli
    The OTUD5 protein is a deubiquitinating enzyme with complex regulatory functions that acts as a negative regulator in the innate immune system. It exhibits peptidase activity against "Lys-48" and "Lys-63" linked polyubiquitin chains, and in vitro, it can cleave "Lys-11" linked ubiquitin chains. OTUD6A Protein, Human is the recombinant human-derived OTUD6A protein, expressed by E. coli , with tag free.
  • HY-P75952
    OTUB1 Protein, Human (His)

    Ubiquitin thioesterase OTUB1; OTUbain-1; OTUB1; OTB1; OTU1

    		 Human E. coli
    OTUB1 protein directly interacts with RNF128, forming a ternary complex with USP8 through OTUB1's binding to the C-terminal UCH catalytic domain of USP8. OTUB1 Protein, Human (His) is the recombinant human-derived OTUB1 protein, expressed by E. coli , with N-His labeled tag.
  • HY-P71182
    OTUB2 Protein, Human (GST)

    Ubiquitin Thioesterase OTUB2; Deubiquitinating Enzyme OTUB2; OTU Comain-Containing Ubiquitin Aldehyde-Binding Protein 2; OTUbain-2; Ubiquitin-Specific-Processing Protease OTUB2; OTUB2; C14orf137; OTB2; OTU2

    		 Human E. coli
    OTUB2 is a hydrolase that efficiently removes conjugated ubiquitin from proteins in vitro, implying a crucial role in preventing protein degradation and regulating turnover. Its deubiquitinating activity targets “Lys-11”, “Lys-48” and “Lys-63” linked polyubiquitin chains, with preference for the latter. OTUB2 Protein, Human (GST) is the recombinant human-derived OTUB2 protein, expressed by E. coli , with N-GST labeled tag.
  • HY-P77118
    OTUB2 Protein, Human (His)

    Ubiquitin thioesterase OTUB2; OTUbain-2; C14orf137; OTB2; OTU2

    		 Human E. coli
    OTUB2 is a hydrolase that efficiently removes conjugated ubiquitin from proteins in vitro, implying a crucial role in preventing protein degradation and regulating turnover. Its deubiquitinating activity targets “Lys-11”, “Lys-48” and “Lys-63” linked polyubiquitin chains, with preference for the latter. OTUB2 Protein, Human (His) is the recombinant human-derived OTUB2 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P701483
    OTUD5 Protein, Human (His, FLAG)

    OTUD5; OTU domain-containing protein 5; Deubiquitinating enzyme A; DUBA

    		 Human E. coli
    The OTUD5 protein is a deubiquitinating enzyme that crucially eliminates the innate immune response through peptidase activity on "Lys-48" and "Lys-63" linked polyubiquitin chains, thereby inhibiting TRAF3-mediated Type I interferon production. It acts as a regulator of neuroectodermal differentiation by cleaving “Lys-48” linked ubiquitin chains to prevent the degradation of chromatin regulators such as ARID1A, HDAC2 and HCF1. OTUD5 Protein, Human (His, FLAG) is the recombinant human-derived OTUD5 protein, expressed by E. coli , with N-6*His, N-Flag labeled tag.
  • HY-P701465
    OTUD7B Protein, Human (sf9)

    OTUD7B; OTU domain-containing protein 7B; Cellular zinc finger anti-NF-kappa-B protein; Cezanne; Zinc finger A20 domain-containing protein 1; Zinc finger protein Cezanne

    		 Human Sf9 insect cells
    The OTUD7B protein acts as a negative regulator to inhibit the non-canonical NF-kappa-B pathway by deubiquitinating TRAF3, thereby inhibiting B cell responses. It prevents degradation of “Lys-48”-linked polyubiquitin chains on TRAF3 during atypical NF-kappa-B stimulation, avoiding overactivation of the pathway and affecting mucosal immunity. OTUD7B Protein, Human (sf9) is the recombinant human-derived OTUD7B protein, expressed by sf9 insect cells , with tag free.
  • HY-P701466
    OTUD7B Protein, Human (sf9, His, StreII)

    OTUD7B; OTU domain-containing protein 7B; Cellular zinc finger anti-NF-kappa-B protein; Cezanne; Zinc finger A20 domain-containing protein 1; Zinc finger protein Cezanne

    		 Human Sf9 insect cells
    The OTUD7B protein acts as a negative regulator to inhibit the non-canonical NF-kappa-B pathway by deubiquitinating TRAF3, thereby inhibiting B cell responses. It prevents degradation of “Lys-48”-linked polyubiquitin chains on TRAF3 during atypical NF-kappa-B stimulation, avoiding overactivation of the pathway and affecting mucosal immunity. OTUD7B Protein, Human (sf9, His, Strep) is the recombinant human-derived OTUD7B protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.

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