OTUD6A Protein, Human
The OTUD5 protein is a deubiquitinating enzyme with complex regulatory functions that acts as a negative regulator in the innate immune system. It exhibits peptidase activity against "Lys-48" and "Lys-63" linked polyubiquitin chains, and in vitro, it can cleave "Lys-11" linked ubiquitin chains. OTUD6A Protein, Human is the recombinant human-derived OTUD6A protein, expressed by E. coli , with tag free.
- Species: Human
- Source: E. coli
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Biological Activity
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Product Properties
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Biological Activity
The OTUD5 protein is a deubiquitinating enzyme with complex regulatory functions that acts as a negative regulator in the innate immune system. It exhibits peptidase activity against "Lys-48" and "Lys-63" linked polyubiquitin chains, and in vitro, it can cleave "Lys-11" linked ubiquitin chains. OTUD6A Protein, Human is the recombinant human-derived OTUD6A protein, expressed by E. coli , with tag free.
OTUD6A is a deubiquitinating enzyme known for its ability to hydrolyze various types of polyubiquitin chains. Specifically, OTUD6A exhibits deubiquitinating activity towards 'Lys-27', 'Lys-29', 'Lys-33', and 'Lys-11'-linked polyubiquitin chains. This enzymatic function involves the cleavage of ubiquitin molecules from substrate proteins, contributing to the regulation of protein degradation and cellular signaling pathways. As a member of the ovarian tumor domain-containing family of deubiquitinases, OTUD6A plays a role in modulating ubiquitin-dependent processes, providing a fine-tuning mechanism for cellular protein homeostasis and signaling.
Technical Parameters
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Species Human
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Source E. coli
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Tag Tag Free
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Accession
Q7L8S5 (M1-L288)
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Gene ID139562
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Molecular Construction
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N-term
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OTUD6A (M1-L288)
Accession # Q7L8S5 -
C-term
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Protein Length
Full Length
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Synonyms
OTUD6A; FLJ25831; OTU Deubiquitinase 6A; OTU Domain Containing 6A; DUBA2; HIN-6 Protease; HSHIN6; DUBA-2; OTU Domain-Containing Protein 6A
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AA Sequence
MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAGAAGGVLPRLL
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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