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Results for "

Salvianolic

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

12

Natural
Products

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-N0318
    Salvianolic acid A
    10+ Cited Publications

    		 MMP Inflammation/Immunology
    Salvianolic acid A could protect the blood brain barrier through matrix metallopeptidase 9 (MMP-9) inhibition and anti-inflammation.
    Salvianolic acid A
  • HY-N1362
    Salvianolic acid B
    Maximum Cited Publications
    20 Publications Verification

    Lithospermic acid B

    		 Autophagy Cardiovascular Disease
    Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.
    Salvianolic acid B
  • HY-N0319
    Salvianolic acid C
    5+ Cited Publications

    		 Cytochrome P450 Cancer
    Salvianolic acid C is a noncompetitive Cytochrome P4502C8 (CYP2C8) inhibitor and a moderate mixed inhibitor of Cytochrome P45022J2 (CYP2J2), with Kis of 4.82 μM and 5.75 μM for CYP2C8 and CYP2J2, respectively.
    Salvianolic acid C
  • HY-125847
    Salvianolic acid F
    1 Publications Verification

    		 Ras PI3K Akt Caspase Apoptosis Bcl-2 Family NF-κB MMP Cancer
    Salvianolic acid F is a KRAS inhibitor, especially for KRAS G12D. Salvianolic acid F inhibits NF-kB, MMP-9, and NO simultaneously. Salvianolic acid F inhibits cancer cell growth, invasion, and migration and induces apoptosis via the EP300/PI3K/AKT pathway in vitro. Salvianolic acid F inhibits the growth of KRAS-dependent lung cancer cells via the PI3K/AKT signaling pathway in vivo. Salvianolic acid F can be used in the research of various cancers, including KRAS G12D-driven non-small cell lung cancer (NSCLC) and ovarian cancer .
    Salvianolic acid F
  • HY-N7880
    Salvianolic acid Y

    		Reactive Oxygen Species (ROS) Cancer
    Salvianolic acid Y is a phenolic acid with the same planar structure as Salvianolic acid B. Salvianolic acid Y rescues cell injury by H2O2 .
    Salvianolic acid Y
  • HY-N0318R
    Salvianolic acid A (Standard)

    		Reference Standards MMP Inflammation/Immunology
    Salvianolic acid A (Standard) is the analytical standard of Salvianolic acid A. This product is intended for research and analytical applications. Salvianolic acid A could protect the blood brain barrier through matrix metallopeptidase 9 (MMP-9) inhibition and anti-inflammation.
    Salvianolic acid A (Standard)
  • HY-N7522
    Salvianolic acid E

    		Others Others
    Salvianolic acid E is a natural compound isolated from Salvia miltiorrhiza .
    Salvianolic acid E
  • HY-13056
    SMND-309
    1 Publications Verification

    		 Drug Metabolite Neurological Disease
    SMND-309 is a metabolite of salvianolic acid B, and exhibits neuroprotective effects in cultured neurons and in permanent middle cerebral artery occlusion rats .
    SMND-309
  • HY-N0320
    Salvianolic acid D

    		Bcl-2 Family Caspase Toll-like Receptor (TLR) MyD88 NF-κB Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Salvianolic acid D is a depside. Salvianolic acid D can be isolated from Salvia miltiorrhiza (Danshen). Salvianolic acid D promotes the expression of Bcl-2, and inhibits the expressions of Bax, Cleaved caspase-3 and -9. Salvianolic acid D reduces the expression levels of TLR4, MyD88 and TRAF6 proteins both in vitro and in vivo, and significantly inhibits the nuclear translocation of NF-κB. Salvianolic acid D inhibits the cytoplasmic translocation of HMGB1. Salvianolic acid D suppresses inflammatory responses and alleviates cerebral ischemia-reperfusion injury. Salvianolic acid D serves as a potential antiplatelet active component .
    Salvianolic acid D
  • HY-N1362R
    Salvianolic acid B (Standard)

    Lithospermic acid B (Standard)

    		 Reference Standards Autophagy Cardiovascular Disease
    Salvianolic acid B (Standard) is the analytical standard of Salvianolic acid B. This product is intended for research and analytical applications. Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.
    Salvianolic acid B (Standard)
  • HY-177249
    Salvianolic acid A derivative-1

    		Arp2/3 Complex Cardiovascular Disease
    Salvianolic acid A derivative-1 (Compound SAA-30) is a orally active derivative of Salvianolic acid A (HY-N0318). Salvianolic acid A derivative-1 binds to transgelin with a KD of 2.39 μM. Salvianolic acid A derivative-1 promotes cell contractions by facilitating the aggregation of actin. Salvianolic acid A derivative-1 can be used for prevention of myocardial ischemia or other diseases associated with IR tissue injuries .
    Salvianolic acid A derivative-1
  • HY-N0320R
    Salvianolic acid D (Standard)

    		Reference Standards Others Cardiovascular Disease
    Salvianolic acid D (Standard) is the analytical standard of Salvianolic acid D. This product is intended for research and analytical applications. Salvianolic acid D, isolated from Salvia miltiorrhiza, is a potential antiplatelet activity compound .
    Salvianolic acid D (Standard)
  • HY-W782096
    Salvianolic acid H

    		Cholinesterase (ChE) Cardiovascular Disease
    Salvianolic acid H is a potent acetylcholinesterase (AChE) inhibitor .
    Salvianolic acid H
  • HY-N0319R
    Salvianolic acid C (Standard)

    		Reference Standards Cytochrome P450 Cancer
    Salvianolic acid C (Standard) is the analytical standard of Salvianolic acid C. This product is intended for research and analytical applications. Salvianolic acid C is a noncompetitive Cytochrome P4502C8 (CYP2C8) inhibitor and a moderate mixed inhibitor of Cytochrome P45022J2 (CYP2J2), with Kis of 4.82 μM and 5.75 μM for CYP2C8 and CYP2J2, respectively.
    Salvianolic acid C (Standard)

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