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Results for "

Swertia

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

9

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7116
    Lawsone methyl ether

    2-​Methoxy-​1,​4-​naphthoquinone

    		 Fungal Bacterial Infection
    Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone), isolated from Impatiens balsamina L. and Swertia calycina, exhibits potent antifungal and antibacterial activities .
    Lawsone methyl ether
  • HY-N11457
    Swertiaside

    		Others Others
    Swertiaside is a natural product, that can be isolated from Swertia mussotii Franch .
    Swertiaside
  • HY-N1994
    Swertianine

    Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect .
    Swertianine
  • HY-N3862
    Erythrodiol 3-O-palmitate

    		Others Cancer
    Erythrodiol 3-O-palmitate is a natural product isolated from Dicranostigma leptopodum (Maxim) Fedde, Gentiana rhodantha Franch or Swertia kouitchensis. Erythrodiol 3-O-palmitate has antitumor activity, and inhibits the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL .
    Erythrodiol 3-O-palmitate
  • HY-N11530
    Kouitchenside G

    		Glucosidase Metabolic Disease
    Kouitchenside G is a natural product that can be isolated from Swertia kouitchensis. Kouitchenside G inhibits α-Glucosidase with an IC50 of 956 μM .
    Kouitchenside G
  • HY-N2872
    Angustin A

    		Others Others
    Angustin A (1,8-Dihydroxy-4,6,7-trimethoxyxanthone) is a xanthones that can be isolated from the aerial parts of Swertia angustifolia .
    Angustin A
  • HY-N1995
    Methylswertianin

    Methylswertianin is an active constituent in Swertia punicea Hemsl, with anti-diabetic effect. Methylswertianin can abates type-2 diabetes, likely via the improvement of insulin resistance (IR) .
    Methylswertianin
  • HY-N11545
    1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone

    		Others Others
    1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone (Compound 18) is a natural product that can be isolated from Swertia mussotii .
    1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone
  • HY-N11512
    α-Glucosidase-IN-24

    		Glucosidase Metabolic Disease
    α-Glucosidase-IN-24 (Compound 13) is an α-Glucosidase inhibitor with an IC50 of 451 μM. α-Glucosidase-IN-24 can be isolated from Swertia kouitchensis .
    α-Glucosidase-IN-24
  • HY-N2050
    1,3,5,8-Tetrahydroxyxanthone
    1 Publications Verification

    Desmethylbellidifolin
    1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity .
    1,3,5,8-Tetrahydroxyxanthone
  • HY-N2000
    Bellidifolin

    Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as a viral protein R (Vpr) inhibitor .
    Bellidifolin
  • HY-N9337
    Amaroswerin

    		NO Synthase Metabolic Disease Inflammation/Immunology Cancer
    Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells .
    Amaroswerin
  • HY-N2447
    Amarogentin
    2 Publications Verification

    		 AMPK Apoptosis Metabolic Disease Cancer
    Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .
    Amarogentin

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