Swertianine
Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect.
For research use only. We do not sell to patients.
- CAS No.: 20882-75-1
- Formula: C14H10O6
- Molecular Weight:274.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| C6 | IC50 |
31.4 μM
Compound: 1
|
Antiproliferative activity against rat C6 cells assessed as cell number after 48 hrs by crystal violet assay
Antiproliferative activity against rat C6 cells assessed as cell number after 48 hrs by crystal violet assay
|
[PMID: 18406151] |
| U-251 | IC50 |
27.3 μM
Compound: 1
|
Antiproliferative activity against human U251 cells assessed as cell number after 48 hrs by crystal violet assay
Antiproliferative activity against human U251 cells assessed as cell number after 48 hrs by crystal violet assay
|
[PMID: 18406151] |
Chemical Information
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CAS No. 20882-75-1
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Molecular Weight 274.23
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Formula C14H10O6
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SMILES
O=C1C2=C(OC3=C1C(O)=CC(OC)=C3)C=CC(O)=C2O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)