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Xanthomonas oryzae pv.oryzae

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Antibiotic (2) Apoptosis (2) Bacterial (17) Fungal (2) Herbicide (1) Reactive Oxygen Species (ROS) (4)
By Research Areas:	Infection (16)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N14257

Andrimid	Bacterial Antibiotic Acetyl-CoA Carboxylase	Infection
Andrimid is a peptide Antibiotic and acetyl-CoA carboxylase inhibitor. Andrimid is produced by symbiotic bacteria of the genus Enterobacter residing in the brown planthopper Nilaparvata lugens. Andrimid exhibits strong specific activity against Xanthomonas campestris pv. oryzae. Andrimid shows no or only weak activity against Gram-positive and Gram-negative bacteria, including most plant pathogenic bacteria. Andrimid can be used in studies related to bacterial infections and rice bacterial blight .

HY-118401

Mansonone E	Fungal Bacterial Herbicide	Infection
Mansonone E (Compound 5) is a pesticide. Mansonone E can be isolated from heartwood of Mansonia gagei. Mansonone E has significant antifungal activity against Cladosporium cucumerinum, Candida albicans and Phytophthora parasitica. Mansonone E has potent antibacterial activity with MIC₅₀s of both 7.8 μg/mL for Xanthomonas oryzae pv. oryzae and X. oryzae* pv. Oryzicola*. Mansonone E also has antifeedant and herbicidal activities .

HY-172793

Antibacterial agent 276	Bacterial Reactive Oxygen Species (ROS) Apoptosis	Infection
Antibacterial agent 276 (compound B3) is an antibacterial agent with EC₅₀ values of 1.32 μg/mL and 2.80 μg/mL against Xanthomonas oryzae pv.oryzae and Xanthomonas axonopodis pv.citri，respectively. Antibacterial agent 276 disrupts the intracellular redox balance, and results in the accumulation of reactive oxygen species (ROS) and subsequent induction of apoptosis .

HY-155644

ROS inducer 1	Bacterial Reactive Oxygen Species (ROS)	Infection
ROS inducer 1 (compound I₂₉) is a fungicide, with EC₅₀ against Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo), and Pseudomonas syringae pv. actinidiae (Psa) of 5.73, 6.62 and 9.05 μg/mL. ROS inducer 1 can effectively induce the production of ROS in Xanthomonas cells and inhibit rice bacterial blight. ROS inducer 1 has the potential to study bacterial infection in crops .

HY-33040

2,2',4'-Trichloroacetophenone	Bacterial	Infection
2,2',4'-Trichloroacetophenone (Compound 3) is an α-haloacetophenone analogue. 2,2',4'-Trichloroacetophenone exhibits good antibacterial activities against Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) with EC₅₀ values of 0.54 and 2.02 mg/L, respectively. 2,2',4'-Trichloroacetophenone can be used for antibacteria study .

HY-168881

Antibacterial agent 262	Bacterial	Infection
Antibacterial agent 262 (compound A23) is a potent antibacterial agent. Antibacterial agent 262 inhibits Xanthomonas oryzae pv oryzae activity. Antibacterial agent 262 inhibits the formation of Xanthomonas oryzae pv oryzae biofilms, disrupting the integrity of bacterial cell membranes .

HY-145325

Antibacterial agent 66	Bacterial	Infection
Antibacterial agent 66 (Compound 6q), a trifluoromethylpyridine 1,3,4-oxadiazole derivative, shows activity against Xanthomonas oryzae pv. oryzae (Xoo) with an EC₅₀ value of 7.2 μg/mL .

HY-161172

Antibacterial agent 178	Bacterial	Infection
Antibacterial agent 178 (compound A10) is a potent antibacterial agent. Antibacterial agent 178 shows antibacterial activities for Xanthomonas oryzae pv. oryzae and Xanthomonas oryzae pv. oryzicola with EC₅₀s of 5.32 mg/L and 7.58 mg/L, respectively. Antibacterial agent 178 targets the translational regulator (CsrA) and the virulence regulator (Xoc3530) .

HY-162624

Quorum sensing-IN-5	Bacterial	Infection
Quorum sensing-IN-5 is a RpfF-targeted quorum-sensing inhibitor. Quorum sensing-IN-5 inhibits Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac) with EC₅₀ values of 9.91 μg/mL and 7.04 μg/mL. Quorum sensing-IN-5 has antimicrobial activity .

HY-178988

Antibacterial agent 299	Bacterial	Infection
Antibacterial agent 299 (Compound P5) is a highly effective antibacterial agent against Xanthomonas oryzae pv. oryzae (Xoo), with an EC₅₀ value of 6.9 μg/mL. Antibacterial agent 299 integrates into bacterial membranes, disrupts membrane structure, inhibits biofilm formation, and thus exerts antibacterial effects. Antibacterial agent 299 also shows inhibitory activity against Xanthomonas oryzae pv. oryzicola (Xoc) (EC₅₀ = 32.5 ± 3.0 μg/mL), but its activity against Xanthomonas axonopodis pv. citri (Xac) is weaker. Antibacterial agent 299 demonstrated excellent control efficacy in a rice bacterial blight (BLB) model. Antibacterial agent 299 can be used for BLB research .

HY-162376

T3SS-IN-4	Bacterial	Infection
T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (X_oo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by X_oo in tobacco and lower the pathogenicity of X_oo in rice .

HY-178212

Antibacterial agent 292	Bacterial Reactive Oxygen Species (ROS) Apoptosis	Infection
Antibacterial agent 292 is a 3-pyrazolylindole derivative. Antibacterial agent 292 is an anti-bacterial agent. Antibacterial agent 292 shows potent inhibitory activity against Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv citri (Xac), with EC₅₀ values of 2.54 and 3.49 μg/mL. Antibacterial agent 292 can suppress biofilm formation, bacterial motility, and extracellular polysaccharide production, induce morphological alterations and promote ROS accumulation, ultimately triggers bacterial apoptosis. Antibacterial agent 292 down-regulates the expression of genes associated with the type VI secretion system (T6SS). Antibacterial agent 292 can be used in rice bacterial blight and citrus canker .

HY-180927

Antibacterial agent 316	Bacterial Fungal	Infection
Antibacterial agent 316 (Compound C1-15) is an antibacterial agent. Antibacterial agent 316 shows antibacterial activity against Xanthomonas oryzae pv oryzae, Xanthomonas axonopodis pv citri, Pseudomonas solanacearum with MICs ranging from 1.56 to 6.25 μg/mL. Antibacterial agent 316 shows antifungal activity against Rhizoctonia solani, Botrytis cinerea .

HY-180999

Antibacterial agent 317	Bacterial	Infection
Antibacterial agent 317 (Compound 5h) is an antibacterial agent. Antibacterial agent 317 has multiple antibacterial mechanisms, including enhancing cell membrane permeability, inhibiting EPS production and cell membrane formation, and also interfering with flagella and methionine biosynthesis. Antibacterial agent 317 significantly suppresses the growth of tested plant pathogens, namely, Xanthomonas oryzae pv oryzicola (Xoc) and Xanthomonas oryzae pv oryzae (Xoo) with EC₅₀ values of 1.53 and 6.07 μg/mL, respectively .

HY-W838632

Antibacterial agent 266	Bacterial Antibiotic	Infection
Antibacterial agent 266 (Compound C5) is a plant pathogen inhibitor that disrupts bacterial integrity, with EC₅₀ values of 24.1 μg/mL and 39.0 μg/mL against Xanthomonas oryzae pv oryzae (Xoo) and X. axonopodis pv citri (Xac), respectively. Antibacterial agent 266 can be used in the development of plant pathology and agricultural antimicrobial agents research .

HY-N18435

Komaroidine	Bacterial Reactive Oxygen Species (ROS)	Infection
Komaroidine is a bactericidal agent. Komaroidine induces reactive oxygen species (ROS) bursts in bacterial cells, disrupts antioxidant enzyme function and redox homeostasis, increases membrane permeability, and triggers bacterial apoptosis. Komaroidine suppresses bacterial burden within infected plant tissues.Komaroidine exhibits broad-spectrum antibacterial activity against phytopathogenic bacteria including Xanthomonas oryzae pv. oryzae, Xanthomonas axonopodis pv. citri, and Pseudomonas syringae pv. actinidiae. Komaroidine can be used for the research of rice bacterial leaf blight .

HY-182364

T3SS-IN-6	Bacterial	Others
T3SS-IN-6 is a thiazolidin-2-cyanamide derivative and type III secretion system (T3SS) inhibitor targeting Xanthomonas oryzae pv. oryzae (Xoo). T3SS-IN-6 exhibits no effect on Xoo growth. T3SS-IN-6 shows no measurable acute toxicity to silkworms and earthworms .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N14257

Andrimid	Structural Classification Natural Products Microorganisms Source Classification	Bacterial Antibiotic Acetyl-CoA Carboxylase
Andrimid is a peptide Antibiotic and acetyl-CoA carboxylase inhibitor. Andrimid is produced by symbiotic bacteria of the genus Enterobacter residing in the brown planthopper Nilaparvata lugens. Andrimid exhibits strong specific activity against Xanthomonas campestris pv. oryzae. Andrimid shows no or only weak activity against Gram-positive and Gram-negative bacteria, including most plant pathogenic bacteria. Andrimid can be used in studies related to bacterial infections and rice bacterial blight .

HY-118401

Mansonone E	Malvaceae Mansonia gagei J.R.Drumm. Quinones Structural Classification Plants Naphthalene Quinones Source Classification	Fungal Bacterial Herbicide
Mansonone E (Compound 5) is a pesticide. Mansonone E can be isolated from heartwood of Mansonia gagei. Mansonone E has significant antifungal activity against Cladosporium cucumerinum, Candida albicans and Phytophthora parasitica. Mansonone E has potent antibacterial activity with MIC₅₀s of both 7.8 μg/mL for Xanthomonas oryzae pv. oryzae and X. oryzae* pv. Oryzicola*. Mansonone E also has antifeedant and herbicidal activities .

HY-N18435

Komaroidine	Structural Classification Alkaloids Nitraria schoberi L. Nitrariaceae Plants Indole Alkaloids Source Classification	Bacterial Reactive Oxygen Species (ROS)
Komaroidine is a bactericidal agent. Komaroidine induces reactive oxygen species (ROS) bursts in bacterial cells, disrupts antioxidant enzyme function and redox homeostasis, increases membrane permeability, and triggers bacterial apoptosis. Komaroidine suppresses bacterial burden within infected plant tissues.Komaroidine exhibits broad-spectrum antibacterial activity against phytopathogenic bacteria including Xanthomonas oryzae pv. oryzae, Xanthomonas axonopodis pv. citri, and Pseudomonas syringae pv. actinidiae. Komaroidine can be used for the research of rice bacterial leaf blight .

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Xanthomonas oryzae pv.oryzae

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