Andrimid
Andrimid is a peptide Antibiotic and acetyl-CoA carboxylase inhibitor. Andrimid is produced by symbiotic bacteria of the genus *Enterobacter* residing in the brown planthopper Nilaparvata lugens. Andrimid exhibits strong specific activity against Xanthomonas campestris pv. oryzae. Andrimid shows no or only weak activity against Gram-positive and Gram-negative bacteria, including most plant pathogenic bacteria. Andrimid can be used in studies related to bacterial infections and rice bacterial blight.
For research use only. We do not sell to patients.
- CAS No.: 108868-95-7
- Formula: C27H33N3O5
- Molecular Weight:479.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
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Biological Activity
Andrimid (0.1 μg/mL) potently inhibits Xanthomonas campestris pv. oryzae strain NIAES 1225 with an MIC of 0.1 μg/mL and shows strong, specific activity against all tested Southeast Asian and Japanese X. campestris pv. oryzae strains, with significantly reduced activity against other bacterial pathovars and pathogens[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 108868-95-7
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Molecular Weight 479.57
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Formula C27H33N3O5
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SMILES
C/C=C/C=C/C=C/C(N[C@H](C1=CC=CC=C1)CC(N[C@@H](C(C)C)C([C@H]2[C@@H](C(NC2=O)=O)C)=O)=O)=O
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Structure Classification
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Initial Source
Erwinia persicina BST187
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Matilla MA, et al. Biosynthesis of the acetyl-CoA carboxylase-inhibiting antibiotic, andrimid in Serratia is regulated by Hfq and the LysR-type transcriptional regulator, AdmX. Environ Microbiol. 2016;18(11):3635-3650. [Content Brief]
[3]. Cheng T, et al. Improved production of andrimid in Erwinia persicina BST187 strain by fermentation optimization. BMC Microbiol. 2023;23(1):268. Published 2023 Sep 25. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Andrimid Related Classifications
HY-N14257 Related Classifications
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- Andrimid
- 108868-95-7
- Bacterial
- Antibiotic
- Acetyl-CoA Carboxylase
- Enterobacter sp.
- Dickeya solani
- Bacillus subtilis
- Xanthomonas campestris pv. campestris
- Xanthomonas campestris pv. oryzae
- Serratia plymuthica A153
- Serratia marcescens MSU97
- acetyl-CoA carboxylase
- Nilaparvata lugens
- fatty acid biosynthesis
- Inhibitor
- inhibitor
- inhibit