country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-178212

Copy Link Print Information

Antibacterial agent 292

Antibacterial agent 292 is a 3-pyrazolylindole derivative. Antibacterial agent 292 is an anti-bacterial agent. Antibacterial agent 292 shows potent inhibitory activity against Xanthomonas oryzae pv oryzae (Xoo) and Xanthomonas axonopodis pv citri (Xac), with EC₅₀ values of 2.54 and 3.49 μg/mL. Antibacterial agent 292 can suppress biofilm formation, bacterial motility, and extracellular polysaccharide production, induce morphological alterations and promote ROS accumulation, ultimately triggers bacterial apoptosis. Antibacterial agent 292 down-regulates the expression of genes associated with the type VI secretion system (T6SS). Antibacterial agent 292 can be used in rice bacterial blight and citrus canker.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 3065015-86-0
Formule: C₂₄H₂₅ClN₆O
Masse moléculaire:448.95

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Antibacterial agent 292 Chemical Structure

CAS No.: 3065015-86-0

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

Antibacterial agent 292 (Compound P16) (3.125-25 μg/mL) inhibits growth of Xoo and Xac cells^[1].
Antibacterial agent 292 (3.125-12.5 μg/mL) increases ROS accumulation and induces apoptosis in Xoo and Xac cells^[1].
Antibacterial agent 292 (3.125-50 μg/mL) inhibits biofilm formation, exopolysaccharide content and motility in Xoo and Xac cells^[1].
Antibacterial agent 292 reduces the expressions of vgrG, hcp, and clpV in T6SS in Xoo cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 3065015-86-0
Masse moléculaire 448.95
Formule C₂₄H₂₅ClN₆O
SMILES

ClC1=CC=C(CN(CC2)CCN2CC(NC3=CC(C4=CNC5=C4C=CC=C5)=NN3)=O)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wu G, et al. Design, Synthesis, and Antibacterial Activity Evaluation and Mechanism of 1-H-Indole-3-pyrazolamide Derivatives Containing Piperazine. J Agric Food Chem. 2025 Sep 24;73(38):24404-24415. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis