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Results for "

cAMP analogue

" in MedChemExpress (MCE) Product Catalog:

26

Inhibitors & Agonists

5

Peptides

4

Isotope-Labeled Compounds

Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-P0036
    Octreotide
    15+ Cited Publications

    SMS 201-995

    		 Somatostatin Receptor Apoptosis Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide
  • HY-107544
    8-pCPT-2'-O-Me-cAMP-AM

    		PKA Metabolic Disease
    8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by interaction with PKA pathway .
    8-pCPT-2'-O-Me-cAMP-AM
  • HY-108742A
    Abaloparatide TFA
    3 Publications Verification

    BA 058 TFA; BIM 44058 TFA

    		 Arrestin PTHR Metabolic Disease Endocrinology Cancer
    Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .
    Abaloparatide TFA
  • HY-134266
    8-Bromo-AMP
    1 Publications Verification

    8-Bromoadenosine 5'-monophosphate; 8-Bromoadenylic acid

    		 Endogenous Metabolite Cardiovascular Disease
    8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides .
    8-Bromo-AMP
  • HY-P0036A
    Octreotide dihydrochloride

    SMS 201-995 dihydrochloride

    		 Somatostatin Receptor Apoptosis Inflammation/Immunology Endocrinology Cancer
    Octreotide (SMS 201-995) hydrochloride is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide hydrochloride can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide hydrochloride increases Gi activity and reduces intracellular cAMP production. Octreotide hydrochloride has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide dihydrochloride
  • HY-134263
    8-Br-cAMP-AM

    		PKA Ras Cardiovascular Disease
    8-Br-cAMP-AM is a cyclic adenosine monophosphate (cAMP) analog that activates two major signal transduction pathways in the heart by mimicking the effects of cAMP: protein kinase A (PKA) and guanosine nucleotide exchange factor (Epac), which is directly activated by cAMP. 8-Br-cAMP-AM can be used to study cardiac ischemia and reperfusion injury .
    8-Br-cAMP-AM
  • HY-P0036B
    Octreotide pamoate

    SMS 201-995 pamoate

    		 Somatostatin Receptor Apoptosis Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide (SMS 201-995) pamoate is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide pamoate can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide pamoate increases Gi activity and reduces intracellular cAMP production. Octreotide pamoate has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide pamoate
  • HY-P0036S4
    Octreotide-d8 acetate

    SMS 201-995-d8 acetate

    		 Isotope-Labeled Compounds Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide-d8 (acetate) (SMS 201-995-d8 (acetate)) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide-d8 acetate
  • HY-134340
    8-pMeOPT-2'-O-Me-cAMP

    8-(4-Methoxyphenylthio)-2'-O-Me-cAMP

    		 Ras Others
    8-pMeOPT-2'-O-Me-cAMP is an analogue of the signal molecule cAMP and a potent stimulator of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP does .
    8-pMeOPT-2'-O-Me-cAMP
  • HY-123396
    8-Chloro-cAMP

    		PKA Cancer
    8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity .
    8-Chloro-cAMP
  • HY-123396A
    8-Chloro-cAMP sodium

    		PKA Cancer
    8-Chloro-cAMP sodium is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP sodium has anticancer activity .
    8-Chloro-cAMP sodium
  • HY-P11246
    A13:B7-24-GG

    		RXFP Receptor Metabolic Disease
    A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a Ki value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (Ki = 602.56 nM) and an inhibitory effect on cAMP (EC50) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC50 of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .
    A13:B7-24-GG
  • HY-134264
    8-Br-2'-O-Me-cAMP

    		Ras Cardiovascular Disease Neurological Disease
    8-Br-2'-O-Me-cAMP is an analogue of the signal molecule cyclic AMP (cAMP). 8-Br-2'-O-Me-cAMP is an agonist of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP do. 8-Br-2'-O-Me-cAMP can be used in cardiovascular disease research .
    8-Br-2'-O-Me-cAMP
  • HY-131766
    2'-O-Me-cAMP

    2'-O-Methyladenosine-3',5'-cyclic monophosphate

    		 Ras Others
    2'-O-Me-cAMP is an analogue of natural signal molecule cAMP and a selective stimulator of the exchange factors activated by cAMP (Epac) with low membrane permeability .
    2'-O-Me-cAMP
  • HY-131772
    2-AHA-cAMP

    		Fluorescent Dye Others
    2-AHA-cAMP is an analogue of natural signal molecule cAMP and an activator of cAMP-dependent protein kinase. 2-AHA-cAMP has a free terminal primary amino group, which can be used for coupling to gels or fluorescent dyes .
    2-AHA-cAMP
  • HY-134308
    8-NBD-cAMP sodium

    		Fluorescent Dye Others
    8-NBD-cAMP sodium is a fluorescently labeled cyclic adenosine phosphate (cAMP) analogue. 8-NBD-cAMP sodium retains a similar biological activity to cAMP, regulating their activity by binding to specific proteins such as EPACs or PKA. 8-NBD-cAMP sodium can be used in fluorescent competitive binding experiments to evaluate the binding affinity of newly synthesized EPAC1 agonists to EPAC1 proteins .
    8-NBD-cAMP sodium
  • HY-134302
    8-HA-cAMP

    8-Hexylamino-cAMP

    		 PKA Others
    8-HA-cAMP is a membrane-permeable cAMP analogue and an activator of cAMP-dependent protein kinase and PKA I. 8-HA-cAMP exerts metabolic stability towards mammalian cyclic nucleotide-responsive phosphodiesterases .
    8-HA-cAMP
  • HY-134298
    8-CPT-6-Phe-cAMP

    8-(4-Chlorophenylthio)-N6-phenyl-cAMP

    		 PKA Others
    8-CPT-6-Phe-cAMP is an analogue of signal molecule cAMP and a potent protein kinase A (PKA) activator .
    8-CPT-6-Phe-cAMP
  • HY-134332
    8-pCPT-5'-AMP

    8-(4-Chlorophenylthio)-5'-AMP

    		 PKA PKG Others
    8-pCPT-5'-AMP is an analogue of 5'-AMP and a lipophilic activator of PKA, PKG and Epac (exchange protein activated by cAMP) .
    8-pCPT-5'-AMP
  • HY-137530
    8-MA-cAMP

    8-Methylamino-cAMP

    		 PKA Others
    8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I .
    8-MA-cAMP
  • HY-106893
    Pimilprost

    SM 10902

    		 Drug Derivative Prostaglandin Receptor Cardiovascular Disease Metabolic Disease
    Pimilprost (SM 10902) is a prostaglandin I1 analogue. Pimilprost exhibits antithrombotic and increases cAMP levels. Pimilprost can promote wound healing through the stimulation of angiogenesis and the improvement of blood flow in diabetic mice. Pimilprost can be used for the research of metabolic and cardiovascular disease, such as diabetes .
    Pimilprost
  • HY-131844
    6-Bnz-5'-AMP

    N6-Benzoyladenosine-5'-O-monophosphate

    		 Endogenous Metabolite Others
    6-Bnz-5'-AMP is a lipophilic analogue of adenosine-5'-O-monophosphate and a potential metabolite of N 6-Benzoyl-cAMP. 6-Bnz-5'-AMP exhibits some cytokinin activity in tobacco and soybean tissue culture assays .
    6-Bnz-5'-AMP
  • HY-134325
    8-OH-cAMP

    8-Hydroxy-cAMP

    		 PKA Cardiovascular Disease Metabolic Disease
    8-OH-cAMP (8-Hydroxy-cAMP) is a polar, membrane-impermeable cyclic adenosine monophosphate analog that is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. As a polar PKA agonist, 8-OH-cAMP is used to study the role of cAMP in the development and progression of cardiovascular and metabolic diseases .
    8-OH-cAMP
  • HY-P0036S2
    Octreotide-d8

    SMS 201-995-d8

    		 Isotope-Labeled Compounds Apoptosis Somatostatin Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide-d8 (SMS 201-995-d8) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide-d8
  • HY-P0036S3
    Octreotide-13C9,15N

    SMS 201-995-13C9，15N

    		 Isotope-Labeled Compounds Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide- 13C9, 15N (SMS 201-995- 13C9, 15N) is 13C and 15N labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
    Octreotide-13C9,15N
  • HY-P0036S
    Octreotide-d8 TFA

    SMS 201-995-d8 TFA

    		 Isotope-Labeled Compounds Somatostatin Receptor Apoptosis Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Octreotide-d8 (SMS 201-995-d8) TFA is the deuterium labeled Octreotide TFA. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide-d8 TFA

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