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Results for "

coat protein

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

1

Fluorescent Dyes

3

Peptides

1

Inhibitory Antibodies

2

Recombinant Proteins

5

Antibodies

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145746
    Sulfo-Cy5 azide

    		Fluorescent Dye PD-1/PD-L1 Inflammation/Immunology Cancer
    Sulfo-Cy5 azide is a near-infrared fluorescent probe with favorable click chemistry reactivity. Sulfo-Cy5 azide enables fluorescence imaging, tissue and cellular visualization of PD-L1 in tumors, and site-specific modification of anti-PD-L1 antibodies. Sulfo-Cy5 azide has been employed for RNA labeling and imaging. Sulfo-Cy5 azide can be conjugated to targeting agents for fluorescence imaging in atherosclerosis and breast cancer models (Ex/Em = 645/670 nm) .
    Sulfo-Cy5 azide
  • HY-P4121
    L17E

    		Potassium Channel Inflammation/Immunology Cancer
    L17E is an attenuated cationic amphiphilic lytic (ACAL) peptide that can be used to deliver a variety of macromolecules, including proteins, antibodies, and DNA nanostructures. L17E inserts and cleaves the membrane structure through electrostatic interaction, enabling intracellular escape. The efficiency of L17E-mediated delivery is strongly correlated with the expression level of KCNN4 (the gene encoding the calcium-activated potassium channel KCa3.1). L17E also promotes the cellular uptake of macromolecules by inducing micropinocytosis. L17E can be further optimized and improved through dimerization strategies and in combination with other delivery systems, such as nuclear localization signal peptides and cell membrane-coated nanoparticles .
    L17E
  • HY-176879
    NHS-PEG2000-Mannose

    		Drug Derivative Bacterial Infection
    NHS-PEG2000-Mannose is an NHS-PEG-Mannose containing PEG2000. NHS-PEG-Mannose is a D-mannose derivative and linker. NHS-PEG-Mannose can bind to phage coat proteins via amino-carboxyl reaction to form mannose-modified phage (Man-phage) .
    NHS-PEG2000-Mannose
  • HY-118112
    4-N-Maleimidobenzoicacid-NHS

    		Biochemical Assay Reagents Others
    4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
    4-N-Maleimidobenzoicacid-NHS
  • HY-162400
    TMV-IN-8

    		TMV Infection
    TMV-IN-8 (compound 7 d) is an anti tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL.TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppressed TMV coat protein gene expression and biosynthesis process .
    TMV-IN-8
  • HY-169425
    TMV-IN-14

    		TMV Infection
    TMV-IN-14 (compound A21) is an agrochemical agent withstrongly interaction between with TMV coat protein through various interactions .
    TMV-IN-14
  • HY-W650842
    Boc-Asp(OBzl)-CMK

    		Caspase Cancer
    Boc-Asp(OBzl)-CMK is an inhibitor for IL-1 converting enzyme (ICE, caspase1). Boc-Asp(OBzl)-CMK prevents death of CHP100 neuroblastoma cell, and IL-1β release elicited by the viral coat protein .
    Boc-Asp(OBzl)-CMK
  • HY-162807
    TMV-IN-10

    		TMV Infection
    TMV-IN-10 (compound 4h) is an arecoline derivative with anti-tobacco mosaic virus (TMV) activity (EC50=146 µg/mL). TMV-IN-10 can be used in research on controlling crop pests and diseases and improving crop yields by acting on the viral coat protein (CP) to cause viral fragmentation .
    TMV-IN-10
  • HY-163754
    TMV-IN-9

    		TMV Infection
    TMV-IN-9 (compound A6) is an antiviral agent that displays excellent inactivating against tobacco mosaic virus (TMV) with an EC50 of 62.8 μg/mL. TMV-IN-9 shows strong binding capacity to TMV coat protein with a binding affinity value of 1.862 μM. TMV-IN-9 obviously destroys the integrity of the TMV particles and blocked the virus from infecting the host .
    TMV-IN-9
  • HY-186069
    NHS-Phosphine

    		Biochemical Assay Reagents Others
    NHS-Phosphine is an amine-reactive compound that can be used to derivatize primary amines of proteins or amine-coated polymer surfaces for ligation to azide-tagged molecules .
    NHS-Phosphine
  • HY-178519
    JQ-1 (carboxylic acid)-NH-C8-COOH

    		Target Protein Ligand-Linker Conjugates Cancer
    JQ-1 (carboxylic acid)-NH-C8-COOH is a synthetic target protein ligand-conjugate linker, which can be used to synthesize JQ1-S(GlcNAc)Cq (HY-178510). JQ1-S(GlcNAc)Cq is a potent Sugar-Coated PROTAC bifunctional degrader with anti-tumor activity .
    JQ-1 (carboxylic acid)-NH-C8-COOH
  • HY-179569
    Antiviral agent 73

    		TMV Infection
    Antiviral agent 73 (compound D13) is a potent intercellular movement inhibitor with antiviral activity. Antiviral agent 73 shows inactivation activity against potato virus Y (PVY) with an EC50 of 79.5 μg/mL. Antiviral agent 73 effectively inhibits virus infection by forming stable hydrogen bonds with Pro154 of PVY coat protein. Antiviral agent 73 can interfere with the process of Pro154-mediated viral intercellular trafficking in plasmodesmata. Antiviral agent 73 can be used for plant virus prevention and control .
    Antiviral agent 73
  • HY-P992055
    Anti-ITGB1 Antibody

    AIIB2

    		 Integrin Caspase Apoptosis Neurological Disease Cancer
    Anti-ITGB1 Antibody (AIIB2) is a monoclonal antibody targeting integrin-β1 (integrin-β1). Anti-ITGB1 Antibody blocks the binding of the ITGB1 subunit to type I collagen ligands, and abrogates the adhesion of cancer cells to type I collagen-coated surfaces. Anti-ITGB1 Antibody inhibits the proliferation and induces apoptosis of human osteosarcoma cells by activating caspase-3 and regulating apoptosis-related proteins. Anti-ITGB1 Antibody is applicable to research related to osteosarcoma and medulloblastoma .
    Anti-ITGB1 Antibody
  • HY-165513
    Niruriside

    		HIV Infection
    Niruriside is a HIV REV/RRE complex inhibitor. Niruriside specifically inhibits the binding interaction between HIV REV protein and RRE RNA, with an IC50 of 3.3 μM, and shows no significant activity against the unrelated R17 capsid protein/operator RNA binding system. At the tested concentrations, Niruriside fails to protect CEM-SS cells from acute HIV-1 infection. Niruriside can be used in the research of human immunodeficiency virus (HIV) infection .
    Niruriside
  • HY-179558
    MS1-96

    		PD-1/PD-L1 Cancer
    MS1-96 is an orally active PD-L1 (programmed death-ligand 1) degrader. MS1-96 effectively reduced PD-L1 protein levels across multiple colorectal cancer (CRC) cell lines. MS1-96 directly binds to PD-L1 (KD = 2.58 μM) and enhances the interaction between HIP1R and PD-L1, thereby altering the intracellular trafficking of PD-L1 within clathrin-coated vesicles. MS1-96 induces abnormal N-glycosylation of PD-L1, destabilizing the protein and hastening its lysosome-mediated degradation. MS1-96 can be used for the study of colorectal cancer .
    MS1-96
  • HY-P11772
    LBP-14

    		Bacterial Infection
    LBP-14, a peptide, is a synthetic fragment of the LPS (HY-D1056) binding protein (LBP) and is a LPS antagonist. LBP-14 interacts with LPS via electrostatic contacts between arginine/lysine residues and LPS phosphate groups, and hydrophobic contacts between aromatic/aliphatic residues and LPS acyl chains, blocking LPS binding to LBP. LBP-14 moderately inhibits LPS-induced TNF-α formation. LBP-14 can be used for the research of gram-negative sepsis .
    LBP-14

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