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Results for "

hPD-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PD-1/PD-L1 (4)
By Research Areas:	Cancer (1) Inflammation/Immunology (3) Metabolic Disease (1)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Human PD-L1 inhibitor I	PD-1/PD-L1	Cancer
Human PD-L1 inhibitor I is a *hPD-1* peptide ligand, with a K_D of 3.39 μM. Human PD-L1 inhibitor I may disturb the binding of hPD-L1 to hPD-1 ^[1].

Human PD-L1 inhibitor V	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor V, a human PD-1 protein binding peptide with a K_d value of 3.32 μM. Human PD-L1 inhibitor V inhibit the interaction of hPD-1/hPD-L1 ^[1].

Human PD-L1 inhibitor IV	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor IV, a polypeptide, is a competitive human PD-1 protein inhibitor with a K_d value of 1.38 μM. Human PD-L1 inhibitor IV inhibits the interaction of hPD-1/hPD-L1 ^[1].

Bicyclopyrone	Others	Metabolic Disease
Bicyclopyrone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (Hpd) .

Human PD-L1 inhibitor V TFA	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor V TFA, a human PD-1 protein binding peptide with a K_d value of 3.32 μM. Human PD-L1 inhibitor V TFA inhibit the interaction of hPD-1/hPD-L1 ^[1].

Cat. No.	Product Name	Target	Research Area

HY-P2474

Human PD-L1 inhibitor I	PD-1/PD-L1	Cancer
Human PD-L1 inhibitor I is a *hPD-1* peptide ligand, with a K_D of 3.39 μM. Human PD-L1 inhibitor I may disturb the binding of hPD-L1 to hPD-1 ^[1].

HY-P2478

Human PD-L1 inhibitor V	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor V, a human PD-1 protein binding peptide with a K_d value of 3.32 μM. Human PD-L1 inhibitor V inhibit the interaction of hPD-1/hPD-L1 ^[1].

HY-P2477

Human PD-L1 inhibitor IV	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor IV, a polypeptide, is a competitive human PD-1 protein inhibitor with a K_d value of 1.38 μM. Human PD-L1 inhibitor IV inhibits the interaction of hPD-1/hPD-L1 ^[1].

HY-P2478A

Human PD-L1 inhibitor V TFA	PD-1/PD-L1	Inflammation/Immunology
Human PD-L1 inhibitor V TFA, a human PD-1 protein binding peptide with a K_d value of 3.32 μM. Human PD-L1 inhibitor V TFA inhibit the interaction of hPD-1/hPD-L1 ^[1].

Species:	Human (8) Rhesus Macaque (2) Rat (2) Mouse (1) Cynomolgus (1) Canine (3)
Tag:	His (11) Avi (3) Fc (8)
Source:	HEK293 (17)

Cat. No.	Compare	Product Name	Species	Source

HY-P70799

	PD-1 Protein, Human (C93S, HEK293, His) Programmed cell death protein 1; PDCD1; PD-1; hPD-1; CD279	Human	HEK293
	PD-1 protein, an inhibitory receptor on T-cells, maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It hinders T-cell activation by associating with CD3-TCR and recruiting PTPN11/SHP-2 for dephosphorylation of key signaling molecules. Tumors exploit PD-1 to weaken anti-tumor immunity, inhibiting CTLs. Blocking PD-1 pathway reverses exhausted T-cell phenotype and enhances anti-tumor response, supporting cancer immunotherapy. PD-1 Protein, Human (C93S, HEK293, His) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-6*His labeled tag and C93S mutation. The total length of PD-1 Protein, Human (C93S, HEK293, His) is 143 a.a., with molecular weight of 23-38 kDa.

HY-P73350

	PD-1 Protein, Rhesus Macaque (HEK293, His) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Rhesus Macaque	HEK293
	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. PDCD1 plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but PDCD1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived PD-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PD-1 Protein, Rhesus Macaque (HEK293, His) is 167 a.a., with molecular weight of 33-50 kDa.

HY-P73725

	PD-1 Protein, Cynomolgus (Biotinylated, 143a.a, HEK293, Fc-Avi) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Cynomolgus	HEK293
	PD-1 is a cell surface receptor on T and B cells that binds to PD-L1 and PD-L2. PD-1 is an immune checkpoint that protects autoimmunity by promoting apoptosis of antigen-specific T cells in lymph nodes (programmed cell death) and reducing apoptosis of regulatory T cells (anti-inflammatory, inhibitory T cells). The expression of PD-L1 on tumor cells inhibits anti-tumor activity through the binding of PD-1 to effector T cells. PD-1 Protein, Cynomolgus (Biotinylated, 143a.a, HEK293, Fc-Avi) is the recombinant cynomolgus-derived PD-1 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of PD-1 Protein, Cynomolgus (Biotinylated, 143a.a, HEK293, Fc-Avi) is 143 a.a., with molecular weight of ~44.5 kDa.

HY-P73346

	PD-1 Protein, Human (167a.a, HEK293, His) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Human	HEK293
	PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (167a.a, HEK293, His) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PD-1 Protein, Human (167a.a, HEK293, His) is 143 a.a., with molecular weight of ~41.1 kDa.

HY-P73349

	PD-1 Protein, Rhesus Macaque (HEK293, Fc) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Rhesus Macaque	HEK293
	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. PDCD1 plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but PDCD1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived PD-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-1 Protein, Rhesus Macaque (HEK293, Fc) is 167 a.a., with molecular weight of ~42.7 kDa.

HY-P73345

	PD-1 Protein, Human (HEK293, His-Fc) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Human	HEK293
	PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (HEK293, His-Fc) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of PD-1 Protein, Human (HEK293, His-Fc) is 143 a.a., with molecular weight of 55-66 kDa.

HY-P77509

	PD-1 Protein, Human (Biotinylated, HEK293, His) Programmed cell death protein 1; hPD-1; PDCD1; CD279	Human	HEK293
	PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PD-1 Protein, Human (Biotinylated, HEK293, His) is 143 a.a., with molecular weight of ~17.4 KDa.

HY-P73348

	PD-1 Protein, Rat (HEK293, Fc) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Rat	HEK293
	Programmed cell death protein 1 (Pdcd1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. Pdcd1plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but Pdcd1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived PD-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-1 Protein, Rat (HEK293, Fc) is 167 a.a., with molecular weight of ~118.8 & 58.4 kDa, respectively.

HY-P73347

	PD-1 Protein, Rat (HEK293, His) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Rat	HEK293
	Programmed cell death protein 1 (Pdcd1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. Pdcd1plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but Pdcd1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Rat (HEK293, His) is the recombinant rat-derived PD-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PD-1 Protein, Rat (HEK293, His) is 143 a.a., with molecular weight of ~30-40 kDa.

HY-P73344

	PD-1 Protein, Human (HEK293, Fc) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Human	HEK293
	PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (HEK293, Fc) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-1 Protein, Human (HEK293, Fc) is 143 a.a., with molecular weight of 55-66 kDa.

HY-P73342

	PD-1 Protein, Canine (HEK293, His) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Canine	HEK293
	The Angiopoietin-1 Protein is a secreted glycoprotein that is a key ligand in the vascular tyrosine kinase signaling pathway. ANGPT1 stimulates angiogenesis by activating PTK2/FAK and downstream kinase MAPK1/ERK2 and MAPK3/ERK1 signaling pathways. ANGPT1 affects the proliferation, migration and differentiation of skeletal muscle cells. PD-1 Protein, Canine (HEK293, His) is the recombinant canine-derived PD-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of PD-1 Protein, Canine (HEK293, His) is 145 a.a., with molecular weight of ~34.88 and 65.02 kDa.

HY-P73341

	PD-1 Protein, Canine (HEK293, Fc) CD279; hPD-1; PDCD1; Programmed cell death 1; SLEB2	Canine	HEK293
	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. PDCD1 plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but PDCD1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Canine (HEK293, Fc) is the recombinant canine-derived PD-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PD-1 Protein, Canine (HEK293, Fc) is 146 a.a., with molecular weight of 55-70 kDa.

HY-P70766

	PD-1 Protein, Human (147a.a, HEK293, His) Programmed cell death protein 1; hPD-1; PDCD1; CD279	Human	HEK293
	PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (147a.a, HEK293, His) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PD-1 Protein, Human (147a.a, HEK293, His) is 147 a.a., with molecular weight of ~38.0 kDa.

HY-P72406

	PD-1 Protein, Human (Biotinylated, HEK293, His-Avi) Programmed cell death protein 1; hPD-1; PDCD1; CD279	Human	HEK293
	PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of PD-1 Protein, Human (Biotinylated, HEK293, His-Avi) is 147 a.a., with molecular weight of 35-45 kDa.

HY-P70525

	PD-1 Protein, Human (HEK293, mFc) Programmed cell death protein 1; hPD-1; PDCD1; CD279	Human	HEK293
	PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (HEK293, mFc) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of PD-1 Protein, Human (HEK293, mFc) is 147 a.a., with molecular weight of 55-70 kDa.

HY-P73724

	PD-1 Protein, Mouse (HEK293, His-Fc) Programmed cell death protein 1; PD1; CD279; PDCD1	Mouse	HEK293
	PD-1 (programmed cell death 1) protein negatively regulates immune responses and affects processes such as apoptosis and tolerance induction. It is a transmembrane protein found on the outside of the plasma membrane and expressed in the retina. PD-1 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived PD-1 protein, expressed by HEK293 , with C-hFc, C-8*His labeled tag. The total length of PD-1 Protein, Mouse (HEK293, His-Fc) is 143 a.a., with molecular weight of 60-65 kDa.

HY-P73727

	PD-1 Protein, Canine (Biotinylated, HEK293, His-Avi) Programmed cell death protein 1; PD1; CD279; PDCD1	Canine	HEK293
	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor which delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2, playing a critical role in induction and maintenance of immune tolerance to self. PDCD1 plays a role in anti-tumor immunity and is involved in safeguarding against autoimmunity, but PDCD1-mediated inhibitory pathway is also exploited by tumors to attenuate anti-tumor immunity. PD-1 Protein, Canine (Biotinylated, HEK293, His-Avi) is the recombinant canine-derived PD-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of PD-1 Protein, Canine (Biotinylated, HEK293, His-Avi) is 168 a.a., with molecular weight of ~19.41 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P81169

PD-1 Antibody Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat(predicted: Cow, Horse, Rabbit)
PD-1 Antibody is an unconjugated, approximately 32 kDa, rabbit-derived, anti-PD-1 polyclonal antibody. PD-1 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: cow, horse, rabbit background without labeling.

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