nuclear stain

Pathways Recommended:	Vitamin D Related/Nuclear Receptor

By Targets:	Amyloid-β (1) CMV (1) DNA/RNA Synthesis (2) Fluorescent Dye (9)
By Research Areas:	Cancer (1) Infection (1)

Targets Recommended: DNA Stain Orphan Nuclear Receptor NF-κB Nuclear Factor of activated T Cells (NFAT) Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0815

Propidium Iodide Maximum Cited Publications 140 Publications Verification	Fluorescent Dye DNA/RNA Synthesis	Others
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.

HY-N0116

Hematoxylin 10+ Cited Publications Natural Black 1; Haematoxylin	Amyloid-β	Others
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC₅₀ of 1.6 μM.

HY-D0944

Giemsa stain 2 Publications Verification	Fluorescent Dye	Others
Giemsa stain is a composite dye composed of methylene azure, methylene blue, eosin and other components. Giemsa stain stains chromatin, nuclear membranes, specific cytoplasmic components and microorganisms. Giemsa stain is used in research on cytological and parasitological staining .

HY-DY1006

Propidium Iodide (solution)	Fluorescent Dye DNA/RNA Synthesis	Others
Propidium Iodide (PI) (solution) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis) , and is often used in flow cytometry analysis. Solvent and Concentration: Sterile water: 1 mg/mL The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-126367

Light green SF yellowish 1 Publications Verification Acid Green 5	Fluorescent Dye	Cancer
Light green SF yellowish (Acid Green 5) is a water-soluble triarylmethane dye. Light green SF yellowish serves as a histological stain that selectively labels mitochondria, collagen, and cartilage, while being an essential component of Papanicolaou staining. Light green SF yellowish is commonly used as a cytoplasmic counterstain for nuclear stains, and is applied in Masson's trichrome staining for collagen fibers, Pap staining, and cytological polychromatic staining in histopathology. Light green SF yellowish also induces growth inhibition and local fibrosarcomas in rats and exerts mild pulmonary tumorigenicity in mice .

HY-W088068

Wright's stain	Fluorescent Dye	Others
Wright's stain is a composite cell stain that mainly binds to intracellular nucleic acids, proteins and other components through thiazine dyes (such as methylene blue) and eosin. Wright's stain is pH-dependent (optimal pH 6.4-6.7) and achieves cell morphology resolution by differentially staining the cytoplasm and nucleus. Under alkaline conditions, thiazine dyes bind to nucleic acids to form purple, and acidic eosin binds to cytoplasmic proteins to form red, which can form contrasting cell morphological features. Wright's stain can clearly display the fine structures of blood cells and bone marrow cells (such as nuclear chromatin and granules) and quickly evaluate cell morphological abnormalities .

HY-117070

TO-PRO-3 iodide	Fluorescent Dye	Others
TO-PRO-3 iodide is a cell-impermeant nucleic acid stain. TO-PRO-3 iodide is useful as a nuclear counterstain and dead cell indicator (Ex/Em = 642/661 nm).

HY-D0946

Azure II	Fluorescent Dye	Others
Azure II is a dye that can be used for nuclear stain .

HY-D1771

Thionin perchlorate	Fluorescent Dye	Others
Thionin perchlorate is a general nuclear stain for chromatin and mucin.

HY-W713888

Aniline blue diammonium	Fluorescent Dye	Others
Aniline blue diammonium is a component of commonly used polychrome stains. Aniline blue diammonium is used to stain collagen fibers in tissue sections using Masson′s trichrome protocol for staining multiple components. Collagen is stained blue by this method. The dye is suitable for selective staining of callose in plant specimens and staining histones for assessing nuclear maturity. Aniline blue diammonium is used in Gomori′s one-step trichrome stain and Mallory′s connective tissue stain for tissue including kidney and intestine.

HY-137889

MLS8969	CMV	Infection
MLS8969 is a selective human cytomegalovirus (HCMV) entry inhibitor with an EC₅₀ of 0.12 μM (HFFs). MLS8969 reduces viral protein levels and inhibits nuclear staining of HCMV pp65. MLS8969 can be used in studies related to human cytomegalovirus infection .

Cat. No.	Product Name	Type

HY-D0815

Propidium Iodide Maximum Cited Publications 140 Publications Verification	Fluorescent Dyes
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.

Propidium Iodide

Maximum Cited Publications

140 Publications Verification

Fluorescent Dyes

Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.

HY-N0116

Hematoxylin 10+ Cited Publications Natural Black 1; Haematoxylin	Fluorescent Dyes
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC₅₀ of 1.6 μM.

HY-D0944

Giemsa stain 2 Publications Verification	Fluorescent Dyes
Giemsa stain is a composite dye composed of methylene azure, methylene blue, eosin and other components. Giemsa stain stains chromatin, nuclear membranes, specific cytoplasmic components and microorganisms. Giemsa stain is used in research on cytological and parasitological staining .

HY-DY1006

Propidium Iodide (solution)	Fluorescent Dyes
Propidium Iodide (PI) (solution) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis) , and is often used in flow cytometry analysis. Solvent and Concentration: Sterile water: 1 mg/mL The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

Propidium Iodide (solution)

Fluorescent Dyes

Propidium Iodide (PI) (solution) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis) , and is often used in flow cytometry analysis.
Solvent and Concentration: Sterile water: 1 mg/mL
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-126367

Light green SF yellowish 1 Publications Verification Acid Green 5	Fluorescent Dyes
Light green SF yellowish (Acid Green 5) is a water-soluble triarylmethane dye. Light green SF yellowish serves as a histological stain that selectively labels mitochondria, collagen, and cartilage, while being an essential component of Papanicolaou staining. Light green SF yellowish is commonly used as a cytoplasmic counterstain for nuclear stains, and is applied in Masson's trichrome staining for collagen fibers, Pap staining, and cytological polychromatic staining in histopathology. Light green SF yellowish also induces growth inhibition and local fibrosarcomas in rats and exerts mild pulmonary tumorigenicity in mice .

Light green SF yellowish

1 Publications Verification

Acid Green 5

Fluorescent Dyes

Light green SF yellowish (Acid Green 5) is a water-soluble triarylmethane dye. Light green SF yellowish serves as a histological stain that selectively labels mitochondria, collagen, and cartilage, while being an essential component of Papanicolaou staining. Light green SF yellowish is commonly used as a cytoplasmic counterstain for nuclear stains, and is applied in Masson's trichrome staining for collagen fibers, Pap staining, and cytological polychromatic staining in histopathology. Light green SF yellowish also induces growth inhibition and local fibrosarcomas in rats and exerts mild pulmonary tumorigenicity in mice .

HY-W088068

Wright's stain	Fluorescent Dyes
Wright's stain is a composite cell stain that mainly binds to intracellular nucleic acids, proteins and other components through thiazine dyes (such as methylene blue) and eosin. Wright's stain is pH-dependent (optimal pH 6.4-6.7) and achieves cell morphology resolution by differentially staining the cytoplasm and nucleus. Under alkaline conditions, thiazine dyes bind to nucleic acids to form purple, and acidic eosin binds to cytoplasmic proteins to form red, which can form contrasting cell morphological features. Wright's stain can clearly display the fine structures of blood cells and bone marrow cells (such as nuclear chromatin and granules) and quickly evaluate cell morphological abnormalities .

Wright's stain

Fluorescent Dyes

Wright's stain is a composite cell stain that mainly binds to intracellular nucleic acids, proteins and other components through thiazine dyes (such as methylene blue) and eosin. Wright's stain is pH-dependent (optimal pH 6.4-6.7) and achieves cell morphology resolution by differentially staining the cytoplasm and nucleus. Under alkaline conditions, thiazine dyes bind to nucleic acids to form purple, and acidic eosin binds to cytoplasmic proteins to form red, which can form contrasting cell morphological features. Wright's stain can clearly display the fine structures of blood cells and bone marrow cells (such as nuclear chromatin and granules) and quickly evaluate cell morphological abnormalities .

HY-117070

TO-PRO-3 iodide	Fluorescent Dyes
TO-PRO-3 iodide is a cell-impermeant nucleic acid stain. TO-PRO-3 iodide is useful as a nuclear counterstain and dead cell indicator (Ex/Em = 642/661 nm).

HY-D1771

Thionin perchlorate	Fluorescent Dyes
Thionin perchlorate is a general nuclear stain for chromatin and mucin.

HY-W713888

Aniline blue diammonium	Fluorescent Dyes
Aniline blue diammonium is a component of commonly used polychrome stains. Aniline blue diammonium is used to stain collagen fibers in tissue sections using Masson′s trichrome protocol for staining multiple components. Collagen is stained blue by this method. The dye is suitable for selective staining of callose in plant specimens and staining histones for assessing nuclear maturity. Aniline blue diammonium is used in Gomori′s one-step trichrome stain and Mallory′s connective tissue stain for tissue including kidney and intestine.

Aniline blue diammonium

Fluorescent Dyes

Aniline blue diammonium is a component of commonly used polychrome stains. Aniline blue diammonium is used to stain collagen fibers in tissue sections using Masson′s trichrome protocol for staining multiple components. Collagen is stained blue by this method. The dye is suitable for selective staining of callose in plant specimens and staining histones for assessing nuclear maturity. Aniline blue diammonium is used in Gomori′s one-step trichrome stain and Mallory′s connective tissue stain for tissue including kidney and intestine.

Cat. No.	Product Name	Type

HY-D0946

Azure II	Biochemical Assay Reagents
Azure II is a dye that can be used for nuclear stain .

Cat. No.	Product Name

HY-K0611

Modified Van Gieson Staining Kit
MCE Modified Van Gieson Staining Kit employs Celestine Blue and Mayer’s hematoxylin for nuclear staining, providing clearer and more stable nuclear visualization while facilitating longer preservation of stained sections. Ponceau S is used for collagen fiber staining, offering stable coloration and strong resistance to fading. This method enables effective differentiation between collagen fibers and muscle fibers, and can assist in distinguishing collagen fiber–derived tumors from myogenic tumors to a certain extent. It is also suitable for observing tissue or organ injury, repair processes, and the degree of fibrosis.

Modified Van Gieson Staining Kit

MCE Modified Van Gieson Staining Kit employs Celestine Blue and Mayer’s hematoxylin for nuclear staining, providing clearer and more stable nuclear visualization while facilitating longer preservation of stained sections. Ponceau S is used for collagen fiber staining, offering stable coloration and strong resistance to fading. This method enables effective differentiation between collagen fibers and muscle fibers, and can assist in distinguishing collagen fiber–derived tumors from myogenic tumors to a certain extent. It is also suitable for observing tissue or organ injury, repair processes, and the degree of fibrosis.

HY-K0609

Modified Masson Staining Kit
MCE Modified Masson Staining Kit employs Celestine Blue hematoxylin for light nuclear staining, offering shorter differentiation time compared to conventional methods. It features low toxicity, environmental friendliness, simple operation, and stable performance. The staining results show clear coloration and high contrast. The stained sections can be stored for long periods with minimal fading, facilitating long-term preservation and image analysis. This kit is widely used in studies of connective tissue, muscle tissue, and collagen fibers, and is suitable for histological observation and related pathological analyses.

Modified Masson Staining Kit

MCE Modified Masson Staining Kit employs Celestine Blue hematoxylin for light nuclear staining, offering shorter differentiation time compared to conventional methods. It features low toxicity, environmental friendliness, simple operation, and stable performance. The staining results show clear coloration and high contrast. The stained sections can be stored for long periods with minimal fading, facilitating long-term preservation and image analysis. This kit is widely used in studies of connective tissue, muscle tissue, and collagen fibers, and is suitable for histological observation and related pathological analyses.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0116

Hematoxylin 10+ Cited Publications Natural Black 1; Haematoxylin	Classification of Application Fields Leguminosae Caesalpinia sappan L. Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Amyloid-β
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC₅₀ of 1.6 μM.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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nuclear stain

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

MCE Kits

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