sign

By Targets:	Androgen Receptor (1) Biochemical Assay Reagents (1) Endogenous Metabolite (3) FGFR (1) Isotope-Labeled Compounds (1) NF-κB (1) PROTACs (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (3) Endocrinology (2) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113405

21-Deoxycortisol

Endogenous Metabolite Endocrinology

21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia .

21-Deoxycortisol	Endogenous Metabolite	Endocrinology
21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia .

HY-113405S1

21-Deoxycortisol-d8	Isotope-Labeled Compounds Endogenous Metabolite	Endocrinology
21-Deoxycortisol-d₈ is the deuterium labeled 21-Deoxycortisol. 21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia[1].

HY-153489A

ISIS 329993 sodium ISIS-CRPRx sodium	Others	Cardiovascular Disease
ISIS 329993 sodium is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx sodium has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis

HY-153489

ISIS 329993 ISIS-CRPRx	Others	Cardiovascular Disease
ISIS 329993 (ISIS-CRPRx) is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis

HY-B0389S19

D-Glucose-13C,d Glucose-¹³C,d; D-(+)-Glucose-¹³C,d; Dextrose-¹³C,d	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose- ¹³C,d is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sign

HY-D0348

Celliton Fast Blue Green B Disperse Blue 7; 1,4-DiOH-5,8-bis(2-OHethyl)aminoanthraquinone	Biochemical Assay Reagents	Others
Celliton Fast Blue Green B (Disperse Blue 7), a blue-green dye used in textiles. The aqueous extract of Celliton Fast Blue Green B causes no signs of skin irritation and sensitization in laboratory animals. Celliton Fast Blue Green B colored textiles with no irritation in human .

HY-132292

ARD-2128	PROTACs Androgen Receptor	Cancer
ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor (AR) degrader. ARD-2128 effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. ARD-2128 has the potential for the research of the prostate cancer .

HY-107818

4-Hydroxychalcone	NF-κB	Cardiovascular Disease Inflammation/Immunology
4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity . 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice .

HY-143881

FGFR4-IN-6	FGFR	Cancer
FGFR4-IN-6 (Compound 9ka) is a covalently reversible FGFR4 inhibitor with an IC₅₀ value of 5.4 nM. FGFR4-IN-6 also exhibits good oral pharmacokinetic properties. FGFR4-IN-6 induces significant tumor regressions in a xenograft mouse model of Hep3B2.1-7 HCC cell line without an obvious sign of toxicity . FGFR4-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name	Target	Research Area

HY-P2459

MOG (35-55), human	Peptides	Neurological Disease
MOG (35-55), human is a component of CNS myelin. MOG (35-55), human is different from mMOG (35-55) by a proline for serine substitution at position 42. MOG (35-55), human is also immunogenic, but not encephalitogenic, and is only partially cross-reactive with mMOG35–55. MOG (35-55), human induces minimal clinical signs of EAE relative to the rodent peptide .

HY-P3628

Dynorphin (2-17) (porcine)	Peptides	Neurological Disease
Dynorphin (2-17) (porcine) is a peptide derived from Prodynorphin, can improve somatic signs of Morphine-dependent withdrawal .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113405

21-Deoxycortisol	Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia .

HY-107818

4-Hydroxychalcone	Cardiovascular Disease Flavonoids Chalcones Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	NF-κB
4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity . 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice .

Species:	Human (4) Rhesus Macaque (2) Mouse (1)
Tag:	His (3) Tag Free (1) Fc (3) Flag (1)
Source:	HEK293 (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P76643

	*DC-SIGN/CD209 Protein, Mouse (HEK293, His)* CD209 antigen; DC-sign1; CD209	Mouse	HEK293
	DC-SIGN/CD209 Protein, a probable pathogen-recognition receptor, mediates the endocytosis and lysosomal degradation of pathogens. It recognizes high mannose N-linked oligosaccharides in pathogen antigens in a calcium-dependent manner and functions as a receptor for ICAM3, potentially through binding to mannose-like carbohydrates. DC-SIGN/CD209 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-His labeled tag. The total length of DC-SIGN/CD209 Protein, Mouse (HEK293, His) is 252 a.a., with molecular weight of ~40 kDa.

HY-P74205

	*DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, His)* CD209 antigen; DC-sign1; CD209	Rhesus Macaque	HEK293
	DC-SIGN/CD209 Protein, is a C-type lectin receptor present on the surface of both macrophages and dendritic cells (DCs), serves as a pivotal pathogen-recognition receptor, playing a crucial role in initiating the primary immune response. It mediates endocytosis and subsequent degradation of pathogens within lysosomal compartments. On DCs, it acts as a high-affinity receptor for ICAM2 and ICAM3, binding to mannose-like carbohydrates. DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-His labeled tag. The total length of DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, His) is 320 a.a., with molecular weight of ~44 kDa.

HY-P70110

	*DC-SIGN/CD209 Protein, Human (HEK293, Fc)* rHuCD209 antigen/CD209, Fc; CD209 molecule; CD209; CDsignHIV gpl20-binding protein; CLEC4L; DCsign; DC-sign; DC-sign1; CD209 Antigen	Human	HEK293
	The DC-SIGN/CD209 protein is expressed on immature dendritic cells (DC) and is an important pathogen recognition receptor that initiates primary immune responses. It mediates endocytosis and subsequent degradation of pathogens within the lysosomal compartment. DC-SIGN/CD209 Protein, Human (HEK293, Fc) is the recombinant human-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of DC-SIGN/CD209 Protein, Human (HEK293, Fc) is 346 a.a., with molecular weight of ~78 kDa.

HY-P76218

	CD299 Protein, Human (HEK293) C-type lectin domain family 4 member M; DC-signR; DC-sign2; L-sign; CD299; CLEC4M; CD209L	Human	HEK293
	CD299 protein showcases an unconventional genetic architecture with a non-canonical intron-exon splice junction, highlighting unique structural features. CD299 Protein, Human (HEK293) is the recombinant human-derived CD299 protein, expressed by HEK293 , with tag free. The total length of CD299 Protein, Human (HEK293) is 322 a.a., with molecular weight of ~37 KDa.

HY-P74206

	*DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, Fc)* CD209 antigen; DC-sign1; CD209	Rhesus Macaque	HEK293
	DC-SIGN/CD209 Protein, is a C-type lectin receptor present on the surface of both macrophages and dendritic cells (DCs), serves as a pivotal pathogen-recognition receptor, playing a crucial role in initiating the primary immune response. It mediates endocytosis and subsequent degradation of pathogens within lysosomal compartments. On DCs, it acts as a high-affinity receptor for ICAM2 and ICAM3, binding to mannose-like carbohydrates. DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, Fc) is 320 a.a., with molecular weight of ~64.9 kDa.

HY-P76219

	CD299 Protein, Human (HEK293, Fc) C-type lectin domain family 4 member M; DC-signR; DC-sign2; L-sign; CD299; CLEC4M; CD209L	Human	HEK293
	The CD299 protein is an important C-type lectin that plays a role in cell adhesion and pathogen recognition. It can identify pathogens such as Mycobacterium tuberculosis, Ebola virus, hepatitis C, HIV-1, influenza A, West Nile virus and SARS-CoV. CD299 Protein, Human (HEK293, Fc) is the recombinant human-derived CD299 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD299 Protein, Human (HEK293, Fc) is 322 a.a., with molecular weight (glycosylation form) of 65.83 kDa.

HY-P72739

	CD299 Protein, Human (HEK293, His-Flag) C-type lectin domain family 4 member M; DC-signR; DC-sign2; L-sign; CD299; CLEC4M; CD209L	Human	HEK293
	CD299 protein showcases an unconventional genetic architecture with a non-canonical intron-exon splice junction, highlighting unique structural features. CD299 Protein, Human (HEK293, His-Flag) is the recombinant human-derived CD299 protein, expressed by HEK293 , with N-Flag, N-8*His labeled tag. The total length of CD299 Protein, Human (HEK293, His-Flag) is 304 a.a., with molecular weight of 35-40 kDa.


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-113405S1

21-Deoxycortisol-d8
21-Deoxycortisol-d₈ is the deuterium labeled 21-Deoxycortisol. 21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia[1].

HY-B0389S19

D-Glucose-13C,d
D-Glucose- ¹³C,d is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sign

Cat. No.	Product Name	Application	Reactivity

HY-P83614

CD209 Antibody (YA3359)

CD209; CLEC4L; CD209 antigen; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-sign; DC-sign1; CD209
WB Human

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Name
Email *

	Sorry, but the email address you supplied was invalid.

sign

Inhibitors & Agonists

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products