2. Membrane Transporter/Ion Channel
  3. EAAT
  4. SLC1A1/EAAT3-IN-1

SLC1A1/EAAT3-IN-1 (Compound 3e) is a selective EAAT3 inhibitor with an IC50 of 7.2  μM for hEAAT3 over EAAT1,2,4 (IC50: ∼ 250 μM). SLC1A1/EAAT3-IN-1 can be used for psychiatric disorders such as obsessive compulsive disorder and schizophrenia research.

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SLC1A1/EAAT3-IN-1

SLC1A1/EAAT3-IN-1 Estructura química

No. CAS : 2387446-20-8

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SLC1A1/EAAT3-IN-1 Related Antibodies

Top Publications Citing Use of Products

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EAAT1 EAAT2 EAAT3 EAAT4 EAAT5

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Descripciòn

SLC1A1/EAAT3-IN-1 (Compound 3e) is a selective EAAT3 inhibitor with an IC50 of 7.2  μM for hEAAT3 over EAAT1,2,4 (IC50: ∼ 250 μM). SLC1A1/EAAT3-IN-1 can be used for psychiatric disorders such as obsessive compulsive disorder and schizophrenia research[1].

IC50 & Target[1]

rEAAT4

∼ 250 μM (IC50)

hEAAT1

∼ 250 μM (IC50)

hEAAT2

∼ 250 μM (IC50)

hEAAT3

7.2 μM (IC50)

Peso molecular

368.23

Fòrmula

C18H14BrN3O
No. CAS
Appearance

Solid

Color

Light yellow to yellow

SMILES

BrC1=CC=CN2C1=NC(C3=CC=CO3)=C2NC4=CC=CC=C4C
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Pureza y Documentación
Referencias
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SLC1A1/EAAT3-IN-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SLC1A1/EAAT3-IN-12387446-20-8EAATExcitatory amino acid transporter Glutamate transporter| InhibitorEAAT3SelectivePsychiatric disordersObsessive compulsive disorderSchizophreniaInhibitorinhibitorinhibit

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Nombre del producto:
SLC1A1/EAAT3-IN-1
Cat. No.:
HY-130125
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