2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Succinic acid tromethamine

Succinic acid tromethamine  (Synonyms: Wormwood acid tromethamine)

Cat. No.: HY-N0420A
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Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries.

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No. CAS : 84540-64-7

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Succinic acid tromethamine Related Antibodies

Top Publications Citing Use of Products

    Succinic acid tromethamine purchased from MedChemExpress. Usage Cited in: Cell Host Microbe. 2023 May 10;31(5):781-797.e9.  [Abstract]

    Relative mRNA expression of IFN-b and cGAS in LoVo cells treated with succinic acid (0.5 mM;24 h) or F. nucleatum supernatant

    Succinic acid tromethamine purchased from MedChemExpress. Usage Cited in: Cell Host Microbe. 2023 May 10;31(5):781-797.e9.  [Abstract]

    Representative immunoblotting of cGAS expression in HT29 and LoVo cells treated with succinic acid (0.5 mM; 24 h).

    Succinic acid tromethamine purchased from MedChemExpress. Usage Cited in: Cell Host Microbe. 2023 May 10;31(5):781-797.e9.  [Abstract]

    Relative mRNA expression of CCL5 and CXCL10 in LoVo cells treated with succinic acid (0.5 mM; 24 h) or F. nucleatum supernatant.

    Succinic acid tromethamine purchased from MedChemExpress. Usage Cited in: Cell Host Microbe. 2023 May 10;31(5):781-797.e9.  [Abstract]

    Relative expression of candidate transcriptional regulation elements in LoVo cells treated with succinic acid (0.5 mM; 24 h).

    Succinic acid tromethamine purchased from MedChemExpress. Usage Cited in: Cell Host Microbe. 2023 May 10;31(5):781-797.e9.  [Abstract]

    Relative cGAS mRNA expression in LoVo cells transfected with EZH2 siRNA, then treated with succinic acid (0.5 mM; 24 h).

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    Descripciòn

    Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[1][2][3].

    IC50 & Target[2]

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    In Vitro

    Succinic acid tromethamine is derived from the fermentation of agricultural carbohydrates[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Succinic acid tromethamine Related Antibodies
    In Vivo

    Succinic acid tromethamine (3, 6 mg/kg; p.o.) increases the percentage of entries into open arms and of time spent on open arms in male mice[3].
    Succinic acid tromethamine (3, 6, 12 mg/kg; i.p.) significant increases in food intake during 5 min, and 40 min after drug administration rectal temperature was measured, succinic acid at a dose of 1.5 mg/kg, inhibited stress-induced hyperthermia[3].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
    Peso molecular

    239.22

    Fòrmula

    C8H17NO7
    No. CAS
    SMILES

    O=C(O)CCC(O)=O.OCC(CO)(N)CO
    Structure Classification
    Initial Source
    Envío

    Room temperature in continental US; may vary elsewhere.
    Almacenamiento

    Please store the product under the recommended conditions in the Certificate of Analysis.
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    Succinic acid tromethamine Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Succinic acid84540-64-7Wormwood acidEndogenous Metaboliteanaerobicfermentationprecursoranxiolyticorally activeInhibitorinhibitorinhibit

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    Nombre del producto:
    Succinic acid tromethamine
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