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tert-butyl-4-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (1) Bacterial (1) Biochemical Assay Reagents (5) COX (2) Drug Derivative (1) Drug Intermediate (17) Drug Metabolite (2) E3 Ligase Ligand-Linker Conjugates (1) Endogenous Metabolite (1) Environmental Pollutants (2) GABA Receptor (1) Histone Methyltransferase (1) Isotope-Labeled Compounds (12) MOFs (3) PROTAC Linkers (89) PROTACs (2) Reference Standards (11) SWI/SNF Complex (1)
By Research Areas:	Cancer (93) Infection (1) Inflammation/Immunology (3) Neurological Disease (1)
Click Chemistry:	PROTAC Synthesis (1)

145

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-69260

tert-Butyl 4-formylpiperidine-1-carboxylate	PROTAC Linkers	Others
tert-Butyl 4-formylpiperidine-1-carboxylate is a PROTAC linker and can be used in the synthesis of PROTAC BRM/BRG1 degrader-3 (HY-168251) .

HY-W012339

tert-Butyl (4-aminobutyl)carbamate hydrochloride N-Boc-putrescine	PROTAC Linkers	Cancer
tert-Butyl (4-aminobutyl)carbamate hydrochloride (N-Boc-putrescine) is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-34415

*4-Bromobutanoic acid tert-butyl* ester** tert-butyl 4-Bromobutyrate	PROTAC Linkers	Cancer
4-Bromobutanoic acid tert-butyl ester (tert-Butyl 4-Bromobutyrate) is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W091986

tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W077402

tert-Butyl 4-(3-bromopropyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(3-bromopropyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-60172

tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate	Drug Intermediate	Others
tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate is a drug intermediate for synthesis of various active compounds.

HY-W018070

tert-Butyl 4-(bromomethyl)benzylcarbamate	PROTAC Linkers	Cancer
tert-Butyl 4-(bromomethyl)benzylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W442050

tert-Butyl 4-(methylamino)butanoate hydrochloride	PROTAC Linkers	Cancer
tert-Butyl 4-(methylamino)butanoate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W045082

tert-Butyl 4-(piperidine-4-carbonyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(piperidine-4-carbonyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W033724

tert-Butyl 4-(piperidin-4-yl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(piperidin-4-yl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W074901

tert-Butyl 4-(piperazin-1-ylmethyl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(piperazin-1-ylmethyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W076878

tert-Butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-33021

tert-Butyl 4-(4-hydroxybutyl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(4-hydroxybutyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-32208

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate	Drug Intermediate	Others
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a drug intermediate for synthesis of various active compounds.

HY-W019095

tert-Butyl 4-hydroxybutanoate	Biochemical Assay Reagents	Others
tert-Butyl 4-hydroxybutanoate is a short aliphatic linker featuring a primary alcohol and a t-butyl ester.

HY-W046402

tert-Butyl 4-(hydroxymethyl)benzylcarbamate	PROTAC Linkers	Cancer
tert-Butyl 4-(hydroxymethyl)benzylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W101721

tert-Butyl (4-chlorobutyl)carbamate	PROTAC Linkers	Cancer
tert-Butyl (4-chlorobutyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W071973

tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(piperazin-1-yl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W087467

tert-Butyl 4-(prop-2-yn-1-yl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(prop-2-yn-1-yl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-33846

tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W005822

tert-Butyl 4-(2-bromoethyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(2-bromoethyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W001613

tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(2-cyanoacetyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W015220

tert-Butyl (4-hydroxybutyl)carbamate	PROTAC Linkers	Cancer
tert-Butyl (4-hydroxybutyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W011657

tert-Butyl 4-(bromomethyl)benzoate	Drug Intermediate	Others
tert-Butyl 4-(bromomethyl)benzoate is a synthetic intermediate useful for compound synthesis .

HY-W042233

tert-Butyl (4-hydroxycyclohexyl)carbamate	PROTAC Linkers	Cancer
tert-Butyl (4-hydroxycyclohexyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W093332

tert-Butyl 4-amino-3-fluorobenzoate	Drug Intermediate	Others
tert-Butyl 4-amino-3-fluorobenzoate is a drug intermediate for synthesis of various active compounds.

HY-W001461

tert-Butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-78698

tert-Butyl (4-(prop-2-yn-1-yloxy)benzyl)carbamate	Drug Intermediate	Others
tert-Butyl (4-(prop-2-yn-1-yloxy)benzyl)carbamate is a drug intermediate for synthesis of various active compounds.

HY-22289

tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate	PROTAC Linkers	Cancer
tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-42363

tert-Butyl 4,4,4-trifluorobut-2-enoate	Drug Intermediate	Others
tert-Butyl 4,4,4-trifluorobut-2-enoate is a drug intermediate for synthesis of various active compounds.

HY-W012020

tert-Butyl 4-(3-hydroxypropyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(3-hydroxypropyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W129547

tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W046163

tert-Butyl 4-(3-aminopropyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(3-aminopropyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W102095

tert-Butyl 4-(4-aminophenoxy)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(4-aminophenoxy)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W054209

tert-Butyl 4-(3-hydroxyprop-1-yn-1-yl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(3-hydroxyprop-1-yn-1-yl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-40180

tert-Butyl 4-(methylamino)butylcarbamate	PROTAC Linkers	Cancer
tert-Butyl 4-(methylamino)butylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W024496

tert-Butyl ((4-oxocyclohexyl)methyl)carbamate	PROTAC Linkers	Cancer
tert-Butyl ((4-oxocyclohexyl)methyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-40179

tert-Butyl (4-aminobutyl)(methyl)carbamate	PROTAC Linkers	Cancer
tert-Butyl (4-aminobutyl)(methyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W892600

tert-Butyl (4-(aminooxy)butyl)carbamate	PROTAC Linkers	Cancer
tert-Butyl (4-(aminooxy)butyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W803700

Tert-butyl (4-(aminomethyl)benzyl)(methyl)carbamate	PROTAC Linkers	Cancer
Tert-butyl (4-(aminomethyl)benzyl)(methyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W003177

tert-Butyl 4-iodopiperidine-1-carboxylate	Biochemical Assay Reagents	Others
tert-Butyl 4-iodopiperidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-21376S

tert-Butyl 4-amino-1H-pyrazole-1-carboxylate-d2	Isotope-Labeled Compounds	Others
tert-Butyl 4-amino-1H-pyrazole-1-carboxylate-d₂ is the deuterium labeled tert-Butyl 4-amino-1H-pyrazole-1-carboxylate.

HY-W042263

tert-Butyl 4-(aminomethyl)-4-fluoropiperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(aminomethyl)-4-fluoropiperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W087218

tert-Butyl 4-(piperidin-3-ylmethyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(piperidin-3-ylmethyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-20669

tert-Butyl 4-(azetidin-3-yl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(azetidin-3-yl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W056396

tert-Butyl 4-(azetidin-3-yl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(azetidin-3-yl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W456646

tert-Butyl 4-(hydroxymethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylate	Drug Intermediate	Others
tert-Butyl 4-(hydroxymethyl)-5-methoxy-7-methyl-1H-indole-1-carboxylate is a drug intermediate for synthesis of various active compounds.

HY-W176791

Tert-butyl 4-(3-chloropropyl)piperazine-1-carboxylate	PROTAC Linkers	Cancer
Tert-butyl 4-(3-chloropropyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W241239

tert-Butyl 4-(2-hydroxyethoxy)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(2-hydroxyethoxy)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W003678

tert-Butyl 4-(4-bromophenyl)piperidine-1-carboxylate	PROTAC Linkers	Cancer
tert-Butyl 4-(4-bromophenyl)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

Cat. No.	Product Name	Target	Research Area

HY-100832A

UNC3866 TFA	Histone Methyltransferase	Cancer
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC₅₀=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010037

*2-(tert-Butyl)-4-methoxyphenol*	Structural Classification Monophenols Classification of Application Fields Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants COX
2-tert-Butyl-4-methoxyphenol is a major component of Butylhydroxyanisole (BHA) (HY-B1066). 2-tert-Butyl-4-methoxyphenol is an antioxidant agent, that inhibits expression of Cox2 and Tnfa genes upon stimulation with Lipopolysaccharides (HY-D1056). 2-tert-Butyl-4-methoxyphenol exhibits anti-inflammatory activity, combined with 2,6-di-tert-butyl-4-methylphenol (BHT) .

HY-W024365

*3-tert-Butyl-4-methoxyphenol*	Monophenols Jatropha curcas Linn. Phenols Euphorbiaceae Plants Source Classification	PROTAC Linkers
3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

HY-W024365R

*3-tert-Butyl-4-methoxyphenol (Standard)*	Monophenols Jatropha curcas Linn. Phenols Euphorbiaceae Plants Source Classification	PROTAC Linkers Reference Standards
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

Cat. No.	Product Name	Chemical Structure

HY-21376S

tert-Butyl 4-amino-1H-pyrazole-1-carboxylate-d2
tert-Butyl 4-amino-1H-pyrazole-1-carboxylate-d₂ is the deuterium labeled tert-Butyl 4-amino-1H-pyrazole-1-carboxylate.

HY-76929S

tert-Butyl 4-aminobenzoate-13C6
tert-Butyl 4-aminobenzoate- ¹³C₆ is the ¹³C labeled tert-Butyl 4-aminobenzoate .

HY-W010037S

*2-(tert-Butyl)-4-methoxyphenol-d3*
2-(tert-Butyl)-4-methoxyphenol-d₃ is deuterium labeled 2-(tert-Butyl)-4-methoxyphenol.

HY-W740068

tert-Butyl 4-Nitrophenyl Carbonate-d9
tert-Butyl 4-Nitrophenyl Carbonate-d₉ is the deuterium labeled Tert-Butyl (4-nitrophenyl) carbonate (HY-W683522).

HY-W024365S

*2-tert-Butyl-4-hydroxyanisole-d3*
2-tert-Butyl-4-hydroxyanisole-d₃ is deuterium labeled 3-tert-Butyl-4-methoxyphenol.

HY-W700253

tert-Butyl 4-methylpiperazine-1-carboxylate-d8
tert-Butyl 4-methylpiperazine-1-carboxylate-d₈ is the deuterium labeled tert-Butyl 4-methylpiperazine-1-carboxylate (HY-W050208).

HY-32208S

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d₄ is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].

HY-W009359S

tert-Butyl 4-benzylpiperazine-1-carboxylate-d8
tert-Butyl 4-benzylpiperazine-1-carboxylate-d₈ is the deuterium labeled tert-Butyl 4-benzylpiperazine-1-carboxylate .

HY-W704049

tert-Butyl 4-(methyl-d3)piperazine-1-carboxylate
tert-Butyl 4-(methyl-d₃)piperazine-1-carboxylate is the deuterium labeled tert-Butyl 4-methylpiperazine-1-carboxylate (HY-W050208).

HY-W283336S

*2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d20*
2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d₂₀ is the deuterium labeled 2,5-Di-tert-butyl-4-methoxyphenol .

HY-W077436S

*2,6-Di-(tert-butyl)-4-methoxyphenol-3,5-d20*
2,6-Di-(tert-butyl)-4-methoxyphenol-3,5-d₂₀ is the deuterium labeled 2,6-Di-tert-butyl-4-methoxyphenol .

HY-W077436S1

Butylated hydroxyanisole-d18
Butylated hydroxyanisole-d₁₈ (2,6-Di-Tert-Butyl-4-Methoxyphenol-d₁₈) is the deuterium labeled Butylated hydroxyanisole.

Cat. No.	Product Name		Classification

HY-114402

ARD-69		PROTAC Synthesis
ARD-69 is a PROTAC degrader based on the E3 ubiquitin ligase VHL and targeting the androgen receptor, which can induce androgen receptor (AR) protein degradation in AR-positive prostate cancer cells. ARD-69 inhibits AR-regulated gene expression, binds to the AR ligand binding domain at one end and binds to VHL at the other end, prompting AR to be recruited to the E3 ubiquitin ligase complex, triggering proteasome degradation, thereby inhibiting AR signaling pathways and downstream gene expression (such as PSA, TMPRSS2). ARD-69 can be used to study of castration-resistant prostate cancer (mCRPC) . ARD-69 is composed of a target protein ligand (pink part) AR antagonist 14 (HY-172624), a PROTAC linker (black part) tert-Butyl 4-ethynyl-[1,4'-bipiperidine]-1'-carboxylate (HY-W442074), and a VHL-type E3 ubiquitinase ligand (blue part) VH 101, acid (HY-47070); among them, the VHL ligand and the linker can form a conjugate VH 101-amide-piperidine-Pip-alkyne (HY-172625).

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tert-butyl-4-

Inhibitors & Agonists

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Isotope-Labeled Compounds

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