tert-Butyl 4-(4-aminophenoxy)piperidine-1-carboxylate
Based on 1 Customer Validation
tert-Butyl 4-(4-aminophenoxy)piperidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 95.18%
- CAS No.: 138227-63-1
- Formula: C16H24N2O3
- Molecular Weight:292.38
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Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E1003 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 138227-63-1
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Appearance Solid
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Molecular Weight 292.38
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Formula C16H24N2O3
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Color Brown to dark brown
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SMILES
O=C(OC(C)(C)C)N1CCC(OC2=CC=C(N)C=C2)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (342.02 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4202 mL | 17.1010 mL | 34.2021 mL | 85.5052 mL |
| 5 mM | 0.6840 mL | 3.4202 mL | 6.8404 mL | 17.1010 mL | |
| 10 mM | 0.3420 mL | 1.7101 mL | 3.4202 mL | 8.5505 mL | |
| 15 mM | 0.2280 mL | 1.1401 mL | 2.2801 mL | 5.7003 mL | |
| 20 mM | 0.1710 mL | 0.8551 mL | 1.7101 mL | 4.2753 mL | |
| 25 mM | 0.1368 mL | 0.6840 mL | 1.3681 mL | 3.4202 mL | |
| 30 mM | 0.1140 mL | 0.5700 mL | 1.1401 mL | 2.8502 mL | |
| 40 mM | 0.0855 mL | 0.4275 mL | 0.8551 mL | 2.1376 mL | |
| 50 mM | 0.0684 mL | 0.3420 mL | 0.6840 mL | 1.7101 mL | |
| 60 mM | 0.0570 mL | 0.2850 mL | 0.5700 mL | 1.4251 mL | |
| 80 mM | 0.0428 mL | 0.2138 mL | 0.4275 mL | 1.0688 mL | |
| 100 mM | 0.0342 mL | 0.1710 mL | 0.3420 mL | 0.8551 mL |
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