4-Bromobutanoic acid tert-butyl ester
Based on 1 Customer Validation
4-Bromobutanoic acid tert-butyl ester (tert-Butyl 4-Bromobutyrate) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 110661-91-1
- Formula: C8H15BrO2
- Molecular Weight:223.11
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E376 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 110661-91-1
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Appearance Liquid (Density: 1.258±0.06 g/cm3)
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Molecular Weight 223.11
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Formula C8H15BrO2
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCCBr
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Synonyms
tert-Butyl 4-Bromobutyrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)