tert-Butyl 4-(2-bromoethyl)piperazine-1-carboxylate
Based on 1 Customer Validation
tert-Butyl 4-(2-bromoethyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 98.83%
- CAS No.: 655225-01-7
- Formula: C11H21BrN2O2
- Molecular Weight:293.21
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
-
Help & FAQs
-
HY-W009426
Cyclo(Phe-Asp)Aspartame Impurity -
HY-W077402
tert-Butyl 4-(3-bromopropyl)piperazine-1-carboxylatePROTAC Linker -
HY-Y0889
1-(2,3-Dichlorphenyl)piperazineDHCR7 Inhibitor -
HY-W105411
N,N'-DiacryloylpiperazineSynthetic Compound -
HY-20128
Piperazin-2-oneIntermediate -
HY-W011726
1-(4-Methoxyphenyl)piperazine hydrochloridePiperazine -
HY-33846
tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylatePROTAC Linker -
HY-W001978
1-(4-Chlorobenzhydryl)piperazineBiochemical Reagent -
HY-W014552
1-(4-Nitrophenyl)piperazinePiperazine Linker -
HY-W016777
2,2'-Piperazine-1,4-diyldiethanolPROTAC Linker -
HY-W012426
1-PiperonylpiperazineBiochemical Reagent -
HY-W015661
3-(Piperazin-1-yl)propan-1-olPROTAC Linker
All PROTAC Linkers Isoforms
More
Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E975 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
CAS No. 655225-01-7
-
Appearance Solid
-
Molecular Weight 293.21
-
Formula C11H21BrN2O2
-
Color White to off-white
-
SMILES
O=C(OC(C)(C)C)N1CCN(CCBr)CC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (341.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (240 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4105 mL | 17.0526 mL | 34.1052 mL | 85.2631 mL |
| 5 mM | 0.6821 mL | 3.4105 mL | 6.8210 mL | 17.0526 mL | |
| 10 mM | 0.3411 mL | 1.7053 mL | 3.4105 mL | 8.5263 mL | |
| 15 mM | 0.2274 mL | 1.1368 mL | 2.2737 mL | 5.6842 mL | |
| 20 mM | 0.1705 mL | 0.8526 mL | 1.7053 mL | 4.2632 mL | |
| 25 mM | 0.1364 mL | 0.6821 mL | 1.3642 mL | 3.4105 mL | |
| 30 mM | 0.1137 mL | 0.5684 mL | 1.1368 mL | 2.8421 mL | |
| 40 mM | 0.0853 mL | 0.4263 mL | 0.8526 mL | 2.1316 mL | |
| 50 mM | 0.0682 mL | 0.3411 mL | 0.6821 mL | 1.7053 mL | |
| 60 mM | 0.0568 mL | 0.2842 mL | 0.5684 mL | 1.4211 mL | |
| 80 mM | 0.0426 mL | 0.2132 mL | 0.4263 mL | 1.0658 mL | |
| 100 mM | 0.0341 mL | 0.1705 mL | 0.3411 mL | 0.8526 mL |
tert-Butyl 4-(2-bromoethyl)piperazine-1-carboxylate Related Classifications
HY-W005822 Related Classifications
Powered by Bioz