2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Vormatrigine

Vormatrigine is an orally active sodium channel inhibitor with anti-epileptic activity. Vormatrigine can be used to study human focal and generalized epilepsy.

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Vormatrigine

Vormatrigine Estructura química

No. CAS : 2392951-18-5

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

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Vormatrigine Related Antibodies

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Descripciòn

Vormatrigine is an orally active sodium channel inhibitor with anti-epileptic activity. Vormatrigine can be used to study human focal and generalized epilepsy[1][2].

In Vitro

Vormatrigine has a specific inhibitory effect on overactive NaV channels in vitro and has a good inhibitory effect in the maximal electroconvulsive seizure (MES) model[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Vormatrigine Related Antibodies
Peso molecular

406.28

Fòrmula

C16H12F6N4O2
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

FC1=C(OCC(F)(F)F)N=CC(C2=CN3C(C(F)(OCC)F)=NN=C3C=C2)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad
In Vitro: 

DMSO : 175 mg/mL (430.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4614 mL 12.3068 mL 24.6136 mL
5 mM 0.4923 mL 2.4614 mL 4.9227 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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C2

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V2

In Vivo Dissolution Calculator
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Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4614 mL 12.3068 mL 24.6136 mL 61.5339 mL
5 mM 0.4923 mL 2.4614 mL 4.9227 mL 12.3068 mL
10 mM 0.2461 mL 1.2307 mL 2.4614 mL 6.1534 mL
15 mM 0.1641 mL 0.8205 mL 1.6409 mL 4.1023 mL
20 mM 0.1231 mL 0.6153 mL 1.2307 mL 3.0767 mL
25 mM 0.0985 mL 0.4923 mL 0.9845 mL 2.4614 mL
30 mM 0.0820 mL 0.4102 mL 0.8205 mL 2.0511 mL
40 mM 0.0615 mL 0.3077 mL 0.6153 mL 1.5383 mL
50 mM 0.0492 mL 0.2461 mL 0.4923 mL 1.2307 mL
60 mM 0.0410 mL 0.2051 mL 0.4102 mL 1.0256 mL
80 mM 0.0308 mL 0.1538 mL 0.3077 mL 0.7692 mL
100 mM 0.0246 mL 0.1231 mL 0.2461 mL 0.6153 mL
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Vormatrigine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vormatrigine2392951-18-5Sodium ChannelNa channelsNa+ channelsSodium channelinhibitorMES modelanti-epilepticInhibitorinhibit

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Nombre del producto:
Vormatrigine
Cat. No.:
HY-159819
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