β-イオノン (Synonyms: β-Ionone)

Name: β-Ionone
Brand: MedChemExpress
SKU: HY-W015084
Rating: 4.5 (1 reviews)

製品番号: HY-W015084 純度: 99.85%: Data Sheet SDS COA 取扱説明書
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β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

β-イオノン 構造式

CAS 番号 : 14901-07-6

容量	価格（税別）	在庫状況	数量
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 27	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 27	在庫あり	Estimated Time of Arrival: December 31
Liquid
100 mg	$25	在庫あり	Estimated Time of Arrival: December 31
200 mg	$40	在庫あり	Estimated Time of Arrival: December 31
500 mg		お問い合わせ
1 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of β-Ionone:

(E)-β-Ionone 在庫あり
(E)-β-Ionone-d₃ 在庫あり
β-Ionone-¹³C₃ お問い合わせ
β-Ionone (Standard) お問い合わせ

顧客検証

•Pharmacol Res. 2025 May 7:107766. [Abstract]

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•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
DU-145	IC₅₀	210 3 Compound: 1	Antiproliferative activity against human DU145 cells after 72 hrs by flow cytometry Antiproliferative activity against human DU145 cells after 72 hrs by flow cytometry	[PMID: 27474930]
DU-145	IC₅₀	210 3 Compound: 1	Antiproliferative activity against human DU145 cells after 72 hrs by flow cytometry Antiproliferative activity against human DU145 cells after 72 hrs by flow cytometry	[PMID: 27474930]
LNCaP	IC₅₀	130 3 Compound: 1	Antiproliferative activity against human LNCAP cells after 72 hrs by flow cytometry Antiproliferative activity against human LNCAP cells after 72 hrs by flow cytometry	[PMID: 27474930]
LNCaP	IC₅₀	130 3 Compound: 1	Antiproliferative activity against human LNCAP cells after 72 hrs by flow cytometry Antiproliferative activity against human LNCAP cells after 72 hrs by flow cytometry	[PMID: 27474930]
LNCaP	IC₅₀	151 3 Compound: Beta-ionone	Cytotoxicity against human LNCAP cells after 72 hrs by MTT assay Cytotoxicity against human LNCAP cells after 72 hrs by MTT assay	[PMID: 19725582]
LNCaP	IC₅₀	151 3 Compound: Beta-ionone	Cytotoxicity against human LNCAP cells after 72 hrs by MTT assay Cytotoxicity against human LNCAP cells after 72 hrs by MTT assay	[PMID: 19725582]
MCF7	IC₅₀	104 3 Compound: 1	Antiproliferative activity against human MCF7 cells Antiproliferative activity against human MCF7 cells	[PMID: 27474930]
MCF7	IC₅₀	104 3 Compound: 1	Antiproliferative activity against human MCF7 cells Antiproliferative activity against human MCF7 cells	[PMID: 27474930]
MDA-MB-435	IC₅₀	42 3 Compound: 1	Growth inhibition of human MDA-MB-435 cells after 7 days relative to control Growth inhibition of human MDA-MB-435 cells after 7 days relative to control	[PMID: 27474930]
PC-3	IC₅₀	130 3 Compound: 1	Antiproliferative activity against human PC3 cells after 72 hrs by flow cytometry Antiproliferative activity against human PC3 cells after 72 hrs by flow cytometry	[PMID: 27474930]
SGC-7901	IC₅₀	174.93 3 Compound: 1	Antiproliferative activity against human SGC7901 cells Antiproliferative activity against human SGC7901 cells	[PMID: 27474930]
SGC-7901	IC₅₀	89 3 Compound: 1	Growth inhibition of human SGC7901 cells after 24 to 48 hrs by MTT assay Growth inhibition of human SGC7901 cells after 24 to 48 hrs by MTT assay	[PMID: 27474930]
MDA-MB-435	IC₅₀	42 3 Compound: 1	Growth inhibition of human MDA-MB-435 cells after 7 days relative to control Growth inhibition of human MDA-MB-435 cells after 7 days relative to control	[PMID: 27474930]
PC-3	IC₅₀	130 3 Compound: 1	Antiproliferative activity against human PC3 cells after 72 hrs by flow cytometry Antiproliferative activity against human PC3 cells after 72 hrs by flow cytometry	[PMID: 27474930]
SGC-7901	IC₅₀	174.93 3 Compound: 1	Antiproliferative activity against human SGC7901 cells Antiproliferative activity against human SGC7901 cells	[PMID: 27474930]
SGC-7901	IC₅₀	89 3 Compound: 1	Growth inhibition of human SGC7901 cells after 24 to 48 hrs by MTT assay Growth inhibition of human SGC7901 cells after 24 to 48 hrs by MTT assay	[PMID: 27474930]

体外実験

β-Ionone is an analog of β-carotenoids which widely distributed in fruit and vegetables^[1].
β-ionone (25, 50, 100 and 200 μM; for 24 and 48 h) inhibits SGC-7901 cell line growth. The measured IC₅₀ value is 89 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

臨床実験

分子量

192.30

分子式

C₁₃H₂₀O

CAS 番号

14901-07-6

Appearance

Liquid (Density: 0.944±0.06 g/cm³)

Color

Colorless to light yellow

SMILES

CC(/C=C/C1=C(C)CCCC1(C)C)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (520.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : 100 mg/mL (520.02 mM; Need ultrasonic)

H₂O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.2002 mL	26.0010 mL	52.0021 mL
5 mM	1.0400 mL	5.2002 mL	10.4004 mL
10 mM	0.5200 mL	2.6001 mL	5.2002 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (13.00 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (13.00 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (13.00 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

純度とドキュメンテーション

純度: 99.85%

Select Batch:

データシート (272 KB) SDS (394 KB)

COA (248 KB) HNMR (228 KB) LCMS (94 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Mahsa Ansari, et al. β-Ionone and Its Analogs as Promising Anticancer Agents. Eur J Med Chem. 2016 Nov 10;123:141-154. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / Ethanol	1 mM	5.2002 mL	26.0010 mL	52.0021 mL	130.0052 mL
	5 mM	1.0400 mL	5.2002 mL	10.4004 mL	26.0010 mL
	10 mM	0.5200 mL	2.6001 mL	5.2002 mL	13.0005 mL
	15 mM	0.3467 mL	1.7334 mL	3.4668 mL	8.6670 mL
	20 mM	0.2600 mL	1.3001 mL	2.6001 mL	6.5003 mL
	25 mM	0.2080 mL	1.0400 mL	2.0801 mL	5.2002 mL
	30 mM	0.1733 mL	0.8667 mL	1.7334 mL	4.3335 mL
	40 mM	0.1300 mL	0.6500 mL	1.3001 mL	3.2501 mL
	50 mM	0.1040 mL	0.5200 mL	1.0400 mL	2.6001 mL
	60 mM	0.0867 mL	0.4334 mL	0.8667 mL	2.1668 mL
	80 mM	0.0650 mL	0.3250 mL	0.6500 mL	1.6251 mL
	100 mM	0.0520 mL	0.2600 mL	0.5200 mL	1.3001 mL

β-Ionone Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量		濃度		体積		分子量 *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）	×	体積 _（開始）	=	濃度 _（終了）	×	体積 _（終了）
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Ionone14901-07-6Environmental PollutantsApoptosisEnvironmental ContaminantsInhibitorinhibitorinhibit

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β-イオノン (Synonyms: β-Ionone)

カスタマーレビュー

Other Forms of β-Ionone:

β-イオノン 関連抗体

顧客検証

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性

純度とドキュメンテーション

参考文献

カスタマーレビュー

β-イオノン 関連抗体

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

β-Ionone Related Classifications

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

Keywords:

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Request for HNMR Report

Request for HNMR Report

β-イオノン関連抗体

β-イオノン関連抗体