1-Methylhistamine dihydrochloride

Name: 1-Methylhistamine dihydrochloride
Brand: MedChemExpress
SKU: HY-W053787
Rating: 4.5 (0 reviews)

Cat. No.: HY-W053787 Purity: 99.89%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

1-Methylhistamine dihydrochloride is a histamine metabolite.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

1-Methylhistamine dihydrochloride 화학구조

CAS No. : 6481-48-7

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기
200 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of 1-Methylhistamine dihydrochloride:

1-Methylhistamine-d₃ dihydrochloride In-stock
1-Methylhistamine dihydrochloride (Standard) In-stock
1-Methylhistamine 견적 받기

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Human Endogenous Metabolite Microbial Metabolite

Biological Activity
순도&문서
References
고객리뷰

제품 설명

1-Methylhistamine dihydrochloride is a histamine metabolite^[1].

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

1-Methylhistamine is a product of histamine 1-methyltransferase in the pathway of histidine metabolism^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

198.09

화학식

C₆H₁₃Cl₂N₃

CAS No.

6481-48-7

Appearance

Solid

Color

Off-white to gray

SMILES

NCCC1=CN(C)C=N1.[H]Cl.[H]Cl

Structure Classification

Others

Initial Source

Endogenous metabolite

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : 62.5 mg/mL (315.51 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.0482 mL	25.2411 mL	50.4821 mL
5 mM	1.0096 mL	5.0482 mL	10.0964 mL
10 mM	0.5048 mL	2.5241 mL	5.0482 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (504.82 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.89%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (246 KB) HNMR (243 KB) RP-HPLC (263 KB) LCMS (85 KB)

Handling Instructions (2659 KB)

References

[1]. Saito K, et al. Determination of urinary excretion of histamine and 1-methylhistamine by liquid chromatography. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):270-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.0482 mL	25.2411 mL	50.4821 mL	126.2053 mL
	5 mM	1.0096 mL	5.0482 mL	10.0964 mL	25.2411 mL
	10 mM	0.5048 mL	2.5241 mL	5.0482 mL	12.6205 mL
	15 mM	0.3365 mL	1.6827 mL	3.3655 mL	8.4137 mL
	20 mM	0.2524 mL	1.2621 mL	2.5241 mL	6.3103 mL
	25 mM	0.2019 mL	1.0096 mL	2.0193 mL	5.0482 mL
	30 mM	0.1683 mL	0.8414 mL	1.6827 mL	4.2068 mL
	40 mM	0.1262 mL	0.6310 mL	1.2621 mL	3.1551 mL
	50 mM	0.1010 mL	0.5048 mL	1.0096 mL	2.5241 mL
	60 mM	0.0841 mL	0.4207 mL	0.8414 mL	2.1034 mL
	80 mM	0.0631 mL	0.3155 mL	0.6310 mL	1.5776 mL
	100 mM	0.0505 mL	0.2524 mL	0.5048 mL	1.2621 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.