Search Result
Results for "
4-aminophenyl-
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-P4070
-
|
|
Insulin Receptor
|
Metabolic Disease
|
|
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
|
-
-
- HY-W011654
-
|
4-aminophenyl-beta-D-galactopyranoside, 98%
|
Glycosidase
|
Inflammation/Immunology
Cancer
|
|
4-Aminophenyl-β-D-galactopyranoside, 98% is a highly efficient substrate for β-galactosidase. It is specifically hydrolyzed by this enzyme to release galactose and electroactive p-aminophenol. 4-Aminophenyl-β-D-galactopyranoside, 98% is widely used in colorimetric and electrochemical assays for detecting β-galactosidase activity and determining enzyme kinetics, such as in biosensing fields including cellular senescence, pathogen and contaminant detection. In addition, since β-galactosidase is often overexpressed in primary ovarian cancer, 4-Aminophenyl-β-D-galactopyranoside, 98% can also be applied to related research on primary ovarian cancer .
|
-
-
- HY-P5362
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Neurological Disease
Cancer
|
|
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
|
-
-
- HY-W076903
-
|
p-Benzoylaniline; 4-aminophenyl phenyl ketone; 4-Benzoylaniline
|
Biochemical Assay Reagents
|
Others
|
|
4-Aminobenzophenone (p-Benzoylaniline; 4-Aminophenyl phenyl ketone; 4-Benzoylaniline) is Benzophenone (HY-Y0546) derivative, which behaves as photosensitizer .
|
-
-
- HY-P2336A
-
|
|
Melanocortin Receptor
|
Cancer
|
|
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
|
-
-
- HY-W035136
-
-
-
- HY-W007620
-
-
-
- HY-W145490
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Aminophenyl β-D-glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-W016549
-
|
|
PROTAC Linkers
|
Cancer
|
|
4-(4-Aminophenyl)butanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-100130
-
-
-
- HY-50187
-
|
|
Drug Intermediate
|
Others
|
|
4-(4-Aminophenyl)morpholin-3-one is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-D0306
-
|
Leucopararosaniline
|
DNA/RNA Synthesis
HCV
|
Infection
|
|
Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.
|
-
-
- HY-P10341
-
|
|
GCGR
|
Metabolic Disease
|
|
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
|
-
-
- HY-18687
-
-
-
- HY-W018722
-
|
|
PROTAC Linkers
|
Cancer
|
|
3-(4-Aminophenyl)propionic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-W005059
-
|
|
PROTAC Linkers
|
Cancer
|
|
2-(4-Aminophenyl)ethanol is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-50187R
-
|
|
Reference Standards
|
|
|
4-(4-Aminophenyl)morpholin-3-one (Standard) is the analytical standard of 4-(4-Aminophenyl)morpholin-3-one. This product is intended for research and analytical applications.
|
-
-
- HY-W140934
-
|
|
Fluorescent Dye
|
Others
|
|
Tris 4-aminophenyl methanol is a triamino-triphenylmethane chloride alkaline dye used to prepare Schiff reagent .
|
-
-
- HY-W069330
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 3-(4-aminophenyl)azetidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-75699
-
|
|
Drug Intermediate
|
Others
|
|
N-(4-Aminophenyl)-N,4-dimethyl-1-piperazineacetamide is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-P10563
-
|
BHV-1100
|
CD38
|
Cancer
|
|
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
|
-
-
- HY-W047324
-
|
4-aminophenylmannoside, 98%
|
Biochemical Assay Reagents
|
Others
|
|
4-Aminophenyl-α-D-mannopyranoside, 98% is a synthetic glycoside primarily used as a molecular tool in biochemical research for studying glycosylation processes and enzyme-substrate interactions.
|
-
-
- HY-75678
-
|
|
Drug Intermediate
|
Others
|
|
Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-W567866
-
-
-
- HY-W342830
-
-
-
- HY-N12456
-
|
|
Others
|
Others
|
|
4-Aminophenyl 6-deoxy-α-L-mannopyranoside is a glycoside that can be isolated from Camellia oleifera seeds.
|
-
-
- HY-W415811
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Aminophenyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
-
- HY-W088288
-
|
|
MOFs
|
Others
|
|
4-(4-AMinophenyl)benzoicacid is a metal-organic framework (MOF).
|
-
-
- HY-P3350
-
|
|
Bacterial
|
Infection
|
|
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
|
-
-
- HY-P11004
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
|
-
-
- HY-105168
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
-
- HY-W703810
-
-
-
- HY-W741338
-
-
-
- HY-P10472
-
|
|
GnRH Receptor
|
Endocrinology
|
|
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
|
-
-
- HY-P4757
-
|
|
Parasite
|
Others
|
|
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
|
-
-
- HY-W071576
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyl 3-(4-aminophenyl)propanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-W018396R
-
|
|
Reference Standards
|
|
|
2,2'-((4-Aminophenyl)azanediyl)diethanol sulfate (Standard) is the analytical standard of 2,2'-((4-Aminophenyl)azanediyl)diethanol sulfate. This product is intended for research and analytical applications.
|
-
-
- HY-P11243
-
|
|
Ephrin Receptor
|
Neurological Disease
|
|
EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .
|
-
-
- HY-P2434
-
|
|
Somatostatin Receptor
|
Neurological Disease
Metabolic Disease
Cancer
|
|
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
|
-
-
- HY-P5362A
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
|
NODAGA-LM3 TFA is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 TFA does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 TFA shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 TFA can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
|
-
-
- HY-W125143
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-W107466
-
|
|
Antibiotic
|
Infection
|
|
4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid is a sulfonamide antiinfective agent .
|
-
-
- HY-Z0128R
-
|
|
Reference Standards
|
|
|
tert-Butyl N-(4-aminophenyl)-N-methylcarbamate (Standard) is the analytical standard of tert-Butyl N-(4-aminophenyl)-N-methylcarbamate. This product is intended for research and analytical applications.
|
-
-
- HY-W127792
-
|
2-[(4-aminophenyl)methyl]butanedioic acid
|
Biochemical Assay Reagents
|
Others
|
|
4-Amino-D,L-benzylsuccinic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-P2075
-
|
|
Renin
|
Endocrinology
|
|
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
|
-
-
- HY-100130R
-
-
-
- HY-W285602
-
-
-
- HY-W564798
-
|
|
MOFs
|
Others
|
|
4-((4-Aminophenyl)ethynyl)benzoic acid is a metal-organic framework (MOF).
|
-
-
- HY-W050294
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 2-(4-aminophenyl)acetate is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-P10876
-
|
|
Amyloid-β
|
Neurological Disease
|
|
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
|
-
- HY-W005059S
-
|
p-aminophenylethanol-d6
|
Isotope-Labeled Compounds
PROTAC Linkers
|
Cancer
|
|
2-(4-Aminophenyl)ethanol-d6 (p-aminophenylethanol-d6) is the deuterium labeled 2-(4-Aminophenyl)ethanol (HY-W005059). 2-(4-Aminophenyl)ethanol is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-W104839
-
|
|
PROTAC Linkers
|
Cancer
|
|
2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-W075283
-
|
1-(4-aminophenyl)-1,2,2-triphenylethene
|
|
Others
|
|
4-(1,2,2-Triphenylvinyl)aniline (1-(4-Aminophenyl)-1,2,2-triphenylethene) is a tetraphenylethene-based aggregation-induced luminescent molecule. 4-(1,2,2-Triphenylvinyl)aniline exhibits weak or no fluorescence in dilute solution/dispersed state, and strong fluorescence with increased quantum yield when aggregated into nanoparticles .
|
-
- HY-W075619
-
|
|
MOFs
|
Others
|
|
4,4',4'',4'''-(1,3,6,8-Pyrenetetrayl)tetrakis[benzenamine] compound with 1,3,6,8-Tetrakis(4-aminophenyl)pyrene is a metal-organic framework (MOF).
|
-
- HY-W099975R
-
|
|
Reference Standards
|
|
|
2-(4-Aminophenyl)butanoic acid (Standard) is the analytical standard of 2-(4-Aminophenyl)butanoic acid. This product is intended for research and analytical applications.
|
-
- HY-W721770
-
-
- HY-I0165R
-
-
- HY-P11488
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
-
- HY-P11485
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
-
- HY-P4948
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0306
-
|
Leucopararosaniline
|
Fluorescent Dye
|
|
Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.
|
| Cat. No. |
Product Name |
Type |
-
- HY-W011654
-
|
4-aminophenyl-beta-D-galactopyranoside, 98%
|
Biochemical Assay Reagents
|
|
4-Aminophenyl-β-D-galactopyranoside, 98% is a highly efficient substrate for β-galactosidase. It is specifically hydrolyzed by this enzyme to release galactose and electroactive p-aminophenol. 4-Aminophenyl-β-D-galactopyranoside, 98% is widely used in colorimetric and electrochemical assays for detecting β-galactosidase activity and determining enzyme kinetics, such as in biosensing fields including cellular senescence, pathogen and contaminant detection. In addition, since β-galactosidase is often overexpressed in primary ovarian cancer, 4-Aminophenyl-β-D-galactopyranoside, 98% can also be applied to related research on primary ovarian cancer .
|
-
- HY-W076903
-
|
p-Benzoylaniline; 4-aminophenyl phenyl ketone; 4-Benzoylaniline
|
Biochemical Assay Reagents
|
|
4-Aminobenzophenone (p-Benzoylaniline; 4-Aminophenyl phenyl ketone; 4-Benzoylaniline) is Benzophenone (HY-Y0546) derivative, which behaves as photosensitizer .
|
-
- HY-W145490
-
|
|
Biochemical Assay Reagents
|
|
4-Aminophenyl β-D-glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W140934
-
|
|
Biochemical Assay Reagents
|
|
Tris 4-aminophenyl methanol is a triamino-triphenylmethane chloride alkaline dye used to prepare Schiff reagent .
|
-
- HY-W047324
-
|
4-aminophenylmannoside, 98%
|
Biochemical Assay Reagents
|
|
4-Aminophenyl-α-D-mannopyranoside, 98% is a synthetic glycoside primarily used as a molecular tool in biochemical research for studying glycosylation processes and enzyme-substrate interactions.
|
-
- HY-W567866
-
-
- HY-W342830
-
-
- HY-W415811
-
|
|
Biochemical Assay Reagents
|
|
4-Aminophenyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
|
-
- HY-W127792
-
|
2-[(4-aminophenyl)methyl]butanedioic acid
|
Biochemical Assay Reagents
|
|
4-Amino-D,L-benzylsuccinic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W285602
-
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4070
-
|
|
Insulin Receptor
|
Metabolic Disease
|
|
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
|
-
- HY-105055
-
|
|
Peptides
|
Cancer
|
|
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
|
-
- HY-P5362
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Neurological Disease
Cancer
|
|
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
|
-
- HY-P2336A
-
|
|
Melanocortin Receptor
|
Cancer
|
|
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
|
-
- HY-W007620
-
-
- HY-P10341
-
|
|
GCGR
|
Metabolic Disease
|
|
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
|
-
- HY-P10563
-
|
BHV-1100
|
CD38
|
Cancer
|
|
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
|
-
- HY-P3350
-
|
|
Bacterial
|
Infection
|
|
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
|
-
- HY-P11004
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
|
-
- HY-105168
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
- HY-P10472
-
|
|
GnRH Receptor
|
Endocrinology
|
|
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
|
-
- HY-P4757
-
|
|
Parasite
|
Others
|
|
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
|
-
- HY-P11243
-
|
|
Ephrin Receptor
|
Neurological Disease
|
|
EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .
|
-
- HY-P2434
-
|
|
Somatostatin Receptor
|
Neurological Disease
Metabolic Disease
Cancer
|
|
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
|
-
- HY-P5362A
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
|
NODAGA-LM3 TFA is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 TFA does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 TFA shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 TFA can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
|
-
- HY-P2075
-
|
|
Renin
|
Endocrinology
|
|
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
|
-
- HY-P10876
-
|
|
Amyloid-β
|
Neurological Disease
|
|
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
|
-
- HY-P11488
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
-
- HY-P11485
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
PSMA
|
Cancer
|
|
JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
|
-
- HY-P4948
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W703810
-
|
|
|
N'-(4-Aminophenyl)-N,N-dimethylacetimidamide-d6 is the deuterium labeled N'-(4-Aminophenyl)-N,N-dimethylacetimidamide.
|
-
-
- HY-W741338
-
|
|
|
4-(4-Aminophenyl)-3-morpholinone-d4 is the deuterium labeled 4-(4-Aminophenyl)morpholin-3-one (HY-50187).
|
-
-
- HY-W005059S
-
|
|
|
2-(4-Aminophenyl)ethanol-d6 (p-aminophenylethanol-d6) is the deuterium labeled 2-(4-Aminophenyl)ethanol (HY-W005059). 2-(4-Aminophenyl)ethanol is a PROTAC linker that can be used in the synthesis of PROTACs.
|
-
-
- HY-W721770
-
|
|
|
3-Aminophenyl-2,4,5,6-d4 4-methylbenzenesulfonate is the deuterium labeled 3-Aminopheny 4-methylbenzenesulfonate.
|
-
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: