1. PROTAC
  2. PROTAC Linkers
  3. tert-Butyl 2-(4-aminophenyl)acetate

tert-Butyl 2-(4-aminophenyl)acetate is a PROTAC linker that can be used in the synthesis of PROTACs.

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tert-Butyl 2-(4-aminophenyl)acetate

tert-Butyl 2-(4-aminophenyl)acetate Chemical Structure

CAS No. : 174579-31-8

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Description

tert-Butyl 2-(4-aminophenyl)acetate is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E918 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

207.27

Formule

C12H17NO2

CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

O=C(OC(C)(C)C)CC1=CC=C(N)C=C1

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Pureté et documentation

Purity: ≥98.0%

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tert-Butyl 2-(4-aminophenyl)acetate Related Classifications

  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
tert-Butyl 2-(4-aminophenyl)acetate
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HY-W050294
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