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  5. Didemnin B

Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Didemnin B Chemical Structure

Didemnin B Chemical Structure

CAS No. : 77327-05-0

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1 mg USD 350 In-stock
5 mg USD 1150 In-stock
10 mg USD 1950 In-stock
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Based on 1 publication(s) in Google Scholar

Didemnin B Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer[1].

In Vitro

Didemnin B has activity against miirine B16 melanoma, P388 leukemia, and M5076 sarcoma[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Didemnin B Related Antibodies
In Vivo

Didemnin B is a potent inhibitor of L1210 growth[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

1112.35

Formula

C57H89N7O15
CAS No.
Appearance

Solid

Color

White to off-white

Structure Classification
Initial Source

Carribean sea tunicate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (89.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8990 mL 4.4950 mL 8.9900 mL
5 mM 0.1798 mL 0.8990 mL 1.7980 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8990 mL 4.4950 mL 8.9900 mL 22.4749 mL
5 mM 0.1798 mL 0.8990 mL 1.7980 mL 4.4950 mL
10 mM 0.0899 mL 0.4495 mL 0.8990 mL 2.2475 mL
15 mM 0.0599 mL 0.2997 mL 0.5993 mL 1.4983 mL
20 mM 0.0449 mL 0.2247 mL 0.4495 mL 1.1237 mL
25 mM 0.0360 mL 0.1798 mL 0.3596 mL 0.8990 mL
30 mM 0.0300 mL 0.1498 mL 0.2997 mL 0.7492 mL
40 mM 0.0225 mL 0.1124 mL 0.2247 mL 0.5619 mL
50 mM 0.0180 mL 0.0899 mL 0.1798 mL 0.4495 mL
60 mM 0.0150 mL 0.0749 mL 0.1498 mL 0.3746 mL
80 mM 0.0112 mL 0.0562 mL 0.1124 mL 0.2809 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Didemnin B77327-05-0OthersmarinetunicateTrididemnincyanophorumcancerInhibitorinhibitorinhibit

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