1. Cell Cycle/DNA Damage Anti-infection
  2. DNA/RNA Synthesis HCV
  3. Tris(4-aminophenyl)methane

Tris(4-aminophenyl)methane  (Synonyms: Leucopararosaniline)

Cat. No.: HY-D0306 Purity: 98.0%
Handling Instructions Technical Support

Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.

For research use only. We do not sell to patients.

Tris(4-aminophenyl)methane

Tris(4-aminophenyl)methane Chemical Structure

CAS No. : 548-61-8

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Based on 1 publication(s) in Google Scholar

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Description

Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.

IC50 & Target

Helicase

 

In Vitro

Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM)[1].
To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

289.38

Formula

C19H19N3

CAS No.
Appearance

Solid

Color

Pale purple to purple

SMILES

NC1=CC=C(C(C2=CC=C(N)C=C2)C3=CC=C(N)C=C3)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (172.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4557 mL 17.2783 mL 34.5566 mL
5 mM 0.6911 mL 3.4557 mL 6.9113 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4557 mL 17.2783 mL 34.5566 mL 86.3916 mL
5 mM 0.6911 mL 3.4557 mL 6.9113 mL 17.2783 mL
10 mM 0.3456 mL 1.7278 mL 3.4557 mL 8.6392 mL
15 mM 0.2304 mL 1.1519 mL 2.3038 mL 5.7594 mL
20 mM 0.1728 mL 0.8639 mL 1.7278 mL 4.3196 mL
25 mM 0.1382 mL 0.6911 mL 1.3823 mL 3.4557 mL
30 mM 0.1152 mL 0.5759 mL 1.1519 mL 2.8797 mL
40 mM 0.0864 mL 0.4320 mL 0.8639 mL 2.1598 mL
50 mM 0.0691 mL 0.3456 mL 0.6911 mL 1.7278 mL
60 mM 0.0576 mL 0.2880 mL 0.5759 mL 1.4399 mL
80 mM 0.0432 mL 0.2160 mL 0.4320 mL 1.0799 mL
100 mM 0.0346 mL 0.1728 mL 0.3456 mL 0.8639 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tris(4-aminophenyl)methane
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