4-Hydroxy-1H-indole-3-carbaldehyde (Synonyms: 4-Hydroxyindole-3-carboxaldehyde)

Cat. No.: HY-W091541 Pureté: 98.13%: Fiche technique
COA

SDS
Instruction de manipulation
FAQs
Technical Support

4-Hydroxy-1H-indole-3-carbaldehyde (4-Hydroxyindole-3-carboxaldehyde) is a plant metabolite. 4-Hydroxy-1H-indole-3-carbaldehyde can be isolated from Capparis spinosa L. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the study of inflammation-related diseases.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

4-Hydroxy-1H-indole-3-carbaldehyde Chemical Structure

CAS No. : 81779-27-3

Size	Stock	Quantité
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
250 mg	En stock	Estimated Time of Arrival: December 31
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
5 g	En stock	Estimated Time of Arrival: December 31
10 g	Obtenir un devis
50 g	Obtenir un devis

or Bulk Inquiry

* Veuillez sélectionner la quantité avant d'ajouter des articles.

This product is a controlled substance and not for sale in your territory.

Other Forms of 4-Hydroxy-1H-indole-3-carbaldehyde:

4-Hydroxy-1H-indole-3-carbaldehyde (Standard) Obtenir un devis

Recommandations en vedette

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Voir tous les produits spécifiques à Isoform Endogenous Metabolite:

Voir toutes les isoformes

Human Endogenous Metabolite Microbial Metabolite

Activité biologique
Pureté et documentation
Références
Avis client

Description

Masse moléculaire

161.16

Formule

C₉H₇NO₂

CAS No.

81779-27-3

Appearance

Solid

Color

Yellow to brown

SMILES

O=CC1=CNC2=C1C(O)=CC=C2

Structure Classification

Initial Source

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvant et solubilité

In Vitro:

DMSO : 9.09 mg/mL (56.40 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.2050 mL	31.0251 mL	62.0501 mL
5 mM	1.2410 mL	6.2050 mL	12.4100 mL
10 mM	0.6205 mL	3.1025 mL	6.2050 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 0.91 mg/mL (5.65 mM); Clear solution

This protocol yields a clear solution of ≥ 0.91 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (9.1 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 0.91 mg/mL (5.65 mM); Clear solution

This protocol yields a clear solution of ≥ 0.91 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (9.1 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Pureté et documentation

Purity: 99.67%

Select Batch:

Fiche technique (279 KB) SDS (394 KB)

COA (257 KB) HNMR (119 KB) RP-HPLC (244 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Haifeng Zhou, et al. Anti-inflammatory effects of caper (Capparis spinosa L.) fruit aqueous extract and the isolation of main phytochemicals. J Agric Food Chem. 2010 Dec 22;58(24):12717-21. [Content Brief]

[2]. Weishan Wang, et al. A single fluorescent probe for imaging ribonucleic acid and sulfur dioxide in living systems and its unique application in tumor and normal cells. J Mater Chem B. 2018 Nov 7;6(41):6607-6614. [Content Brief]

[3]. Kdimy A, et al. Phytochemistry, Biological Activities, Therapeutic Potential, and Socio-Economic Value of the Caper Bush (Capparis Spinosa L.). Chem Biodivers. 2022 Oct;19(10):e202200300. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.2050 mL	31.0251 mL	62.0501 mL	155.1253 mL
	5 mM	1.2410 mL	6.2050 mL	12.4100 mL	31.0251 mL
	10 mM	0.6205 mL	3.1025 mL	6.2050 mL	15.5125 mL
	15 mM	0.4137 mL	2.0683 mL	4.1367 mL	10.3417 mL
	20 mM	0.3103 mL	1.5513 mL	3.1025 mL	7.7563 mL
	25 mM	0.2482 mL	1.2410 mL	2.4820 mL	6.2050 mL
	30 mM	0.2068 mL	1.0342 mL	2.0683 mL	5.1708 mL
	40 mM	0.1551 mL	0.7756 mL	1.5513 mL	3.8781 mL
	50 mM	0.1241 mL	0.6205 mL	1.2410 mL	3.1025 mL

4-Hydroxy-1H-indole-3-carbaldehyde Related Classifications

Inflammation/Immunology Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Hydroxy-1H-indole-3-carbaldehyde81779-27-34-Hydroxyindole-3-carboxaldehydeEndogenous Metaboliteplantmetabolitefluorescentprobe inflammation-relatedInhibitorinhibitorinhibit

Vos produits récemment consultés:

Nom du produit

Requested Quantity *

Nom du demandeur *

Civilité

Adresse e-mail *

Numéro de téléphone *

Department

Nom de l'organisation *

City

État

Country or Region *

Remarques

Nom du produit

Lot #

Nom du demandeur *

Adresse e-mail *

Numéro de téléphone

Department *