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AZD-5991 S-enantiomer 

Cat. No.: HY-101533B
Handling Instructions

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.

For research use only. We do not sell to patients.

AZD-5991 S-enantiomer Chemical Structure

AZD-5991 S-enantiomer Chemical Structure

CAS No. : 2143061-82-7

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Other Forms of AZD-5991 S-enantiomer:

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  • Technical Information

  • Purity & Documentation

  • References

Description

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.

IC50 & Target[1]

Mcl-1

6.3 μM (IC50)

Mcl-1

0.98 μM (Kd)

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4875 mL 7.4376 mL 14.8752 mL
5 mM 0.2975 mL 1.4875 mL 2.9750 mL
10 mM 0.1488 mL 0.7438 mL 1.4875 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

672.26

Formula

C₃₅H₃₄ClN₅O₃S₂

CAS No.

2143061-82-7

SMILES

O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
AZD-5991 S-enantiomer
Cat. No.:
HY-101533B
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AZD-5991 S-enantiomer

Cat. No.: HY-101533B