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  3. AZD-5991 S-enantiomer

AZD-5991 S-enantiomer 

Cat. No.: HY-101533B
Handling Instructions

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.

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AZD-5991 S-enantiomer Chemical Structure

AZD-5991 S-enantiomer Chemical Structure

CAS No. : 2143061-82-7

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Description

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.

IC50 & Target[1]

Mcl-1

6.3 μM (IC50)

Mcl-1

0.98 μM (Kd)

Molecular Weight

672.26

Formula

C₃₅H₃₄ClN₅O₃S₂

CAS No.

2143061-82-7

SMILES

O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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AZD-5991 S-enantiomer
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