2143061-82-7
2143061-82-7
Chemical Structure
AZD-5991 (S-enantiomer)
- CAS No.: 2143061-82-7
- Formula:C35H34ClN5O3S2
- Molecular Weight:672.26
IUPAC Name: (Z)-16-chloro-11,21,25,61-tetramethyl-11H,21H,61H-10-oxa-4,8-dithia-1(7,3)-indola-2(4,3),6(3,5)-dipyrazola-9(3,1)-naphthalenacyclotridecaphane-12-carboxylic acid
InChIKey: KBQCEQAXHPIRTF-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5
Biological Activity: AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD-5991 (S-enantiomer) | 99.83% | AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay. | ||||||||||||||||||||
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