D-Fructose-6-phosphate

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D-Fructose 6-phosphate is an endogenous metabolite. D-Fructose 6-phosphate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (D-Fructose-6-phosphate disodium) that retains the same biological activity.

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D-Fructose-6-phosphate Estructura química

No. CAS : 643-13-0

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Other In-stock Forms of D-Fructose-6-phosphate:

D-Fructose-6-phosphate disodium D-Fructose-6-phosphate disodium hydrate

Other Forms of D-Fructose-6-phosphate:

D-Fructose-6-phosphate-¹³C₆ disodium x.hydrate In-stock
D-Fructose-6-phosphate disodium In-stock
D-Fructose-6-phosphate disodium hydrate In-stock
D-Fructose-6-phosphate disodium monohydrate-¹³C₆ Obtener un presupuesto
D-Fructose-6-phosphate disodium monohydrate Obtener un presupuesto

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Descripciòn	D-Fructose 6-phosphate is an endogenous metabolite. D-Fructose 6-phosphate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia^[1]^[2]^[3]^[4].
In Vitro	D-Fructose-6-phosphate (3.2 mM; room temperature) can detect transaldolase TAL activity^[3]. D-Fructose-6-phosphate (10 mM; incubation at 37°C for 60 min) can complete the detection of glucosamine-6-phosphate synthase activity^[4]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. D-Fructose-6-phosphate Related Antibodies
Peso molecular	260.14
Fòrmula	C₆H₁₃O₉P
No. CAS	643-13-0
Appearance	Solid
Color	White to off-white
SMILES	OCC([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=O
Initial Source	Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureza y Documentación	Ficha de datos (267 KB) SDS (252 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Lee JH, et al. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. [Content Brief] [2]. Hardie DG, et al. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):251-62. [Content Brief] [3]. Puskas F, et al. Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C. FASEB J. 2000 Jul;14(10):1352-61. [Content Brief] [4]. Hiramatsu M, et al. Suppression by thyroid hormones of glucosamine-6-phosphate synthetase activity in rat sublingual glands. Arch Oral Biol. 1984;29(10):849-51. [Content Brief]