643-13-0
Chemical Structure
D-Fructose-6-phosphate
- CAS No.: 643-13-0
- Formula:C6H13O9P
- Molecular Weight:260.14
IUPAC Name: (2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl dihydrogen phosphate
InChIKey: GSXOAOHZAIYLCY-HSUXUTPPSA-N
SMILES: OCC([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=O
Biological Activity: D-Fructose 6-phosphate is an endogenous metabolite. D-Fructose 6-phosphate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia[1][2][3][4].
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D-Fructose-6-phosphate | D-Fructose 6-phosphate is an endogenous metabolite. D-Fructose 6-phosphate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia. | |||||||||||||||||||||
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D-Fructose-6-phosphate disodium monohydrate-13C6 | D-Fructose-6-phosphate disodium monohydrate-13C6 is the 13C-labeled D-Fructose-6-phosphate disodium monohydrate (HY-113407C). D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine. | |||||||||||||||||||||
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D-Fructose-6-phosphate-13C6 disodium x.hydrate | 99.9% | D-Fructose-6-phosphate-13C6 disodium x.hydrate is a 13C-labeled D-Fructose-6-phosphate disodium x.hydrate. | ||||||||||||||||||||
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References
- [1]. Lee JH, et al. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. [Content Brief]
- [2]. Hardie DG, et al. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):251-62. [Content Brief]
- [3]. Puskas F, et al. Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C. FASEB J. 2000 Jul;14(10):1352-61. [Content Brief]
- [4]. Hiramatsu M, et al. Suppression by thyroid hormones of glucosamine-6-phosphate synthetase activity in rat sublingual glands. Arch Oral Biol. 1984;29(10):849-51. [Content Brief]
