Glycerol
Based on 2 publication(s) in Google Scholar
Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 56-81-5
- Formula: C3H8O3
- Molecular Weight:92.09
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocol
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Glycerol
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
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Human Endogenous Metabolite |
Glycerol is often included in polyacrylamide gels to prevent dissociation of nucleosomes and other protein-DNA complexes during electrophoresis. With glycerol included, fractionation seems to be largely based on particle mass and charge. The concentration of glycerol during electrophoresis strongly affects the separation characteristics of polyacrylamide gels[1]. Glycerol is an inevitable by-product of oils/fats processing, regardless of the pathway. Fermentative metabolism of glycerol has been studied in great detail in several species of the Enterobacteriaceae family, such as Citrobacter freundii and Klebsiella pneumoniae. The use of anaerobic fermentation to convert abundant and low-priced glycerol streams generated in the production of biodiesel into higher value products represents a promising route to achieve economic viability in the biofuels industry[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 56-81-5
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Appearance Liquid (Density: 1.26 g/cm3)
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Molecular Weight 92.09
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Formula C3H8O3
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Color Colorless to light yellow
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SMILES
OCC(O)CO
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Synonyms
Trihydroxypropane
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
Targeting glutaryl-CoA dehydrogenase-driven acetyl coenzyme A acetyltransferase 2 crotonylation dysregulates cholesterol metabolism in pancreatic cancer cells. [Abstract]2026 Jan;335(Pt 2):149182. PMID: 41285334 -
ACS Appl Mater Interfaces
Kidney Targeting Liposomes Loaded with the Antioxidant Pinocembrin for Treatment of Acute Kidney Injury. [Abstract]2026 Jan 21;18(2):3527-3538. PMID: 41510988
Solvent & Solubility
DMSO : 200 mg/mL (2171.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocol
Rats: Experimental acute renal failure was induced in male Wistar rats 230-300 g by an injection of glycerol dissolved in saline (50% v/v, 10 mL/kg) into the leg muscle after a 24-h period of water deprivation[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (397 KB)
- English - EN (397 KB)
- Français - FR (397 KB)
- Deutsch - DE (397 KB)
- Norwegian - NO (397 KB)
- Español - ES (397 KB)
- Swedish - SV (397 KB)
- Italian - IT (397 KB)
- Korean - KR (397 KB)
- Portuguese - PT (397 KB)
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Handling Instructions (2659 KB)
References
[1]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72. [Content Brief]
[2]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun;18(3):213-9. [Content Brief]
[3]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20;406(3):453-60. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.8589 mL | 54.2947 mL | 108.5894 mL | 271.4736 mL |
| 5 mM | 2.1718 mL | 10.8589 mL | 21.7179 mL | 54.2947 mL | |
| 10 mM | 1.0859 mL | 5.4295 mL | 10.8589 mL | 27.1474 mL | |
| 15 mM | 0.7239 mL | 3.6196 mL | 7.2393 mL | 18.0982 mL | |
| 20 mM | 0.5429 mL | 2.7147 mL | 5.4295 mL | 13.5737 mL | |
| 25 mM | 0.4344 mL | 2.1718 mL | 4.3436 mL | 10.8589 mL | |
| 30 mM | 0.3620 mL | 1.8098 mL | 3.6196 mL | 9.0491 mL | |
| 40 mM | 0.2715 mL | 1.3574 mL | 2.7147 mL | 6.7868 mL | |
| 50 mM | 0.2172 mL | 1.0859 mL | 2.1718 mL | 5.4295 mL | |
| 60 mM | 0.1810 mL | 0.9049 mL | 1.8098 mL | 4.5246 mL | |
| 80 mM | 0.1357 mL | 0.6787 mL | 1.3574 mL | 3.3934 mL | |
| 100 mM | 0.1086 mL | 0.5429 mL | 1.0859 mL | 2.7147 mL |
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