Glycerol-13C3
Based on 1 Customer Validation
Glycerol-13C3 is the 13C labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 63346-81-6
- Formula: 13C3H8O3
- Molecular Weight:95.07
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 63346-81-6
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Unlabeled Cas 56-81-5
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Appearance Liquid
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Molecular Weight 95.07
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Formula 13C3H8O3
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Color Colorless to light yellow
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SMILES
O[13CH2][13CH](O)[13CH2]O
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Synonyms
Trihydroxypropane-13C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : ≥ 100 mg/mL (1051.86 mM)
DMSO : 100 mg/mL (1051.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72. [Content Brief]
[3]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun18(3):213-9. [Content Brief]
[4]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20406(3):453-60. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 10.5186 mL | 52.5928 mL | 105.1857 mL | 262.9641 mL |
| 5 mM | 2.1037 mL | 10.5186 mL | 21.0371 mL | 52.5928 mL | |
| 10 mM | 1.0519 mL | 5.2593 mL | 10.5186 mL | 26.2964 mL | |
| 15 mM | 0.7012 mL | 3.5062 mL | 7.0124 mL | 17.5309 mL | |
| 20 mM | 0.5259 mL | 2.6296 mL | 5.2593 mL | 13.1482 mL | |
| 25 mM | 0.4207 mL | 2.1037 mL | 4.2074 mL | 10.5186 mL | |
| 30 mM | 0.3506 mL | 1.7531 mL | 3.5062 mL | 8.7655 mL | |
| 40 mM | 0.2630 mL | 1.3148 mL | 2.6296 mL | 6.5741 mL | |
| 50 mM | 0.2104 mL | 1.0519 mL | 2.1037 mL | 5.2593 mL | |
| 60 mM | 0.1753 mL | 0.8765 mL | 1.7531 mL | 4.3827 mL | |
| 80 mM | 0.1315 mL | 0.6574 mL | 1.3148 mL | 3.2871 mL | |
| 100 mM | 0.1052 mL | 0.5259 mL | 1.0519 mL | 2.6296 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.