2. Natural Products
  3. Plants
  4. Amaranthaceae

Amaranthaceae

 

Amaranthaceae (40):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0131
    Stigmasterol 83-48-7 99.26%
    Stigmasterol is an orally acitve, immunomodulatory agent with anti-inflammatory and neuroprotective effect, as well as able to cross the blood-brain barrier. Stigmasterol activates AMPK, which in turn inhibits NF-κB and NLRP3 signaling pathways, reduces microglia-mediated neuroinflammation, and alleviates cognitive impairment and Alzheimer's disease. Stigmasterol regulates M1/M2 polarization of microglia through the TLR4/ NF-κB pathway, thereby reducing neuropathic pain. Stigmasterol can be used for neurodegenerative diseases, inflammatory diseases, and pain management, among others.
    Stigmasterol
  • HY-N0211
    Cyasterone 17086-76-9 99.58%
    Cyasterone, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae). Cyasterone manifests anti-proliferation effect by induced apoptosis and cell cycle arrests. Cyasterone may serves as a therapeutic anti-tumor agent against human tumors.
    Cyasterone
  • HY-N0818
    Chikusetsusaponin Iva 51415-02-2 99.61%
    Chikusetsusaponin IVa is an orally active protein kinase activator. Chikusetsusaponin IVa binds to YAP with a KD value of 0.388 mM. Chikusetsusaponin IVa reduces inflammatory mediators (IL-6, IL-10, COX-2) expression, NO production, promotes ROS generation, induces Apoptosis, inhibits MAPK, TAZ, and regulates Nrf2, JAK/STAT. Chikusetsusaponin Iva has anti-H9N2 AIV and anti-endometrial cancer activities. Chikusetsusaponin Iva shows anti-inflammatory, hepatoprotective and osteoprotective effects.
    Chikusetsusaponin Iva
  • HY-N0131R
    Stigmasterol (Standard) 83-48-7
    Stigmasterol (Standard) is the analytical standard of Stigmasterol (HY-N0131). This product is intended for research and analytical applications. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.
    Stigmasterol (Standard)
  • HY-N12586
    Pheophytin a 603-17-8
    Pheophytin a is a multi-target inhibitor, anticancer agent, antioxidant and antiviral agent. Pheophytin a directly binds to and inhibits HCV-NS3/4A protease (IC50=0.89 μM) to block viral replication. Pheophytin a also scavenges free radicals, reduces ferric ions, and exhibits cytotoxic activity against breast cancer cells. Pheophytin a effectively inhibits LPS-induced production of nitric oxide, prostaglandin E2, NOS2 and COX-2, as well as various pro-inflammatory cytokines, by downregulating the transcription levels of inflammatory mediators and blocking the ERK1/2 and STAT-1 pathways. In a low nerve growth factor environment, Pheophytin a also enhances ERK1/2 phosphorylation and synergistically promotes neurite outgrowth through MAPK pathway. Pheophytin a can be used to investigate the pathogenic mechanisms of diseases including chronic hepatitis C, sepsis, breast cancer and Alzheimer's disease.
    Pheophytin a
  • HY-W170614
    Citramalic acid 597-44-4
    Citramalic acid is an organic acid and soil phosphorus-solubilizing agent. Citramalic acid can be secreted by beet roots, and low phosphorus conditions promote its secretion.
    Citramalic acid
  • HY-N17475
    5,7,3-Trihydroxy-6-methoxycoumaronochromone 132915-55-0
    5,7,3-Trihydroxy-6-methoxycoumaronochromone (Compound 7) is a flavonoid C-glycoside analog found in plants of the Amaranthaceae family.
    5,7,3-Trihydroxy-6-methoxycoumaronochromone
  • HY-N17736
    Chikusetsusaponin IVa methyl ester 58546-61-5
    Chikusetsusaponin IVa methyl ester (CME) is a natural triterpenoid saponin compound. Chikusetsusaponin IVa methyl ester induces G0/G1 cell cycle arrest and apoptosis in colon cancer cells by inhibiting the Wnt/β-catenin signaling pathway. By inhibiting the NF-κB and AP-1 signaling pathways, Chikusetsusaponin IVa methyl ester significantly reduces the production of NO, PGE₂ and pro-inflammatory cytokines (TNF-α, IL-6, IL-1β), and downregulates the levels of iNOS and COX-2. Chikusetsusaponin IVa methyl ester can be used in researches on colorectal cancer and inflammation.
    Chikusetsusaponin IVa methyl ester
  • HY-N3770
    (E)-Docosyl caffeate 28593-92-2
    (E)-Docosyl caffeate (compound 1) can be isolated from the halophytic plant Halocnemum strobilaceum.
    (E)-Docosyl caffeate
  • HY-N4130
    25S-Inokosterone 19595-18-7 99.47%
    25S-Inokosterone is a phytoecdysone in the roots of two same species of A. bidentata Blume and A. japonica Nakai, and two different species of C. capitata Moq and C. officinalis Kuan. 25S-Inokosterone has the potential for the LPS-induced acute kidney injury research.
    25S-Inokosterone
  • HY-N7026
    Celosin I 1807732-38-2 99.91%
    Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.
    Celosin I
  • HY-N8382
    Chalepensin 13164-03-9 98.98%
    Chalepensin is a nematicide and CYP inhibitor. Chalepensin inhibits CYP2A6, CYP1A1, CYP1A2, CYP2A13, CYP2C9, CYP2D6, CYP2E1, and CYP3A4 to varying degrees, with IC50 values of 82.3 μM, 2.86 μM, 3.01 μM, 0.21 μM, 6.58 μM, 1.67 μM, 61.1 μM, and 61.7 μM, respectively. Chalepensin potently and selectively kills third-stage infective larvae of Strongyloides venezuelensis.
    Chalepensin
  • HY-N7952
    Achyranthoside D 168009-91-4 98.74%
    Achyranthoside D is a triterpene saponin from Achyranthes root.
    Achyranthoside D
  • HY-N7635
    Oleanolic acid 28-O-β-D-glucopyranoside 14162-53-9 99.42%
    Oleanolic acid 28-O-β-D-glucopyranoside (β-D-Glucopyranosyl oleanolate) is an orally active pentacyclic triterpenoid compound. Oleanolic acid 28-O-β-D-glucopyranoside has anti-inflammatory effects. In ulcerative colitis models, Oleanolic acid 28-O-β-D-glucopyranoside can inhibit the inflammatory response, enhance the intestinal epithelial barrier function, and modulate the gut microbiota. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways. Oleanolic acid 28-O-β-D-glucopyranoside can be used in the research of diseases such as colitis.
    Oleanolic acid 28-O-β-D-glucopyranoside
  • HY-N7919
    Celosin H 1623405-28-6 99.85%
    Celosin H is a hepatoprotective triterpenoid saponin that can be isolated from Celosiae Semen.
    Celosin H
  • HY-N4131
    25R-Inokosterone 19682-38-3 98.76%
    25R-Inokosterone is a phytoecdysone isolated from Achyranthis Radix.
    25R-Inokosterone
  • HY-N15155
    Vitexin 7-O-β-D-glucopyranoside 35109-95-6
    Vitexin 7-O-β-D-glucopyranoside (Vitexin 7-glucoside) is a flavone glycoside found in Beta vulgaris var. cicla. Vitexin 7-O-β-D-glucopyranoside shows a hepatoprotective activity in primary cultured rat hepatocytes with Carbon tetrachloride (CCl4) (HY-Y0298)-induced cell toxicity.
    Vitexin 7-O-β-D-glucopyranoside
  • HY-N12503
    Patuletin 519-96-0
    Patuletin is a flavonol, that can be isolated from the flowers of Tagetes patula. Patuletin shows anti-proliferative activity against cancer cells. Patuletin causes significant nuclear fragmentation and has a great capacity to induce caspase-3 activation.
    Patuletin
  • HY-N12277
    Celosin K 1950579-53-9 99.82%
    Celosin K (compound 8) can be isolated from the seeds of Semen Celosiae. Celosin K is a potent inhibitor of neuron injury elicited by t-BHP. Celosin K inhibits oxidative stress and apoptosis, and acts of autophagy.
    Celosin K
  • HY-N17594
    Achyranthoside A 2231304-39-3
    Achyranthoside A is an isoflavone glycoside isolated from the roots of Achyranthes bidentata. Achyranthoside A inhibits NO production in macrophages treated with LPS (HY-D1056). Achyranthoside A can be used in the study of inflammatory diseases.
    Achyranthoside A