- Natural Products
- Plants
- Amaranthaceae
- Alternanthera philoxeroides (Mart.) Griseb.
Alternanthera philoxeroides (Mart.) Griseb.
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Alternanthera philoxeroides (Mart.) Griseb. (5)
- Formula: C42H66O14
- Molecular Weight: 794.97
Chikusetsusaponin IVa is an orally active protein kinase activator. Chikusetsusaponin IVa binds to YAP with a KD value of 0.388 mM. Chikusetsusaponin IVa reduces inflammatory mediators (IL-6, IL-10, COX-2) expression, NO production, promotes ROS generation, induces Apoptosis, inhibits MAPK, TAZ, and regulates Nrf2, JAK/STAT. Chikusetsusaponin Iva has anti-H9N2 AIV and anti-endometrial cancer activities. Chikusetsusaponin Iva shows anti-inflammatory, hepatoprotective and osteoprotective effects.
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- Formula: C21H20O9
- Molecular Weight: 416.38
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- Formula: C19H21NO5
- Molecular Weight: 343.37
N-trans-Feruloyl-3-methyldopamine (compound 4) is an anticancer compound isolated from Alternanthera philoxeroides. N-trans-Feruloyl-3-methyldopamine is cytotoxic to HeLa cells, with an inhibition rate of 72.2% at a concentration of 30 μg/mL.
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- Formula: C42H66O14
- Molecular Weight: 794.97
Chikusetsusaponin Iva (Standard) is the analytical standard of Chikusetsusaponin Iva. This product is intended for research and analytical applications.
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