2. Infection

Infection (感染症)

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

製品番号 製品名 CAS 番号 純度 構造式
  • HY-128429R
    Trans-​2-​Hexenal (Standard) 6728-26-3 99.90%
    Trans-​2-​Hexenal (Standard) is the analytical standard of Trans-​2-​Hexenal. This product is intended for research and analytical applications. Trans-​2-​Hexenal can be used for the determination of low-molecular-weight carbonyl compounds which are reactive with biological nucleophiles in biological samples.
    Trans-​2-​Hexenal (Standard)
  • HY-130402A
    Propamidine isethionate 140-63-6
    Propamidine (isethionate) is an agent in the diamidine class. Propamidine (isethionate) can be used in research of Acanthamoeba keratitis.
    Propamidine isethionate
  • HY-136081A
    Hexamidine diisethionate 659-40-5 98.75%
    Hexamidine diisethionate is an antimicrobial agent targeting Acanthamoeba protozoa. Hexamidine diisethionate is promising for research of ocular infectious diseases such as Acanthamoeba keratitis.
    Hexamidine diisethionate
  • HY-136409R
    N-Decanoyl-L-homoserine lactone (Standard) 177315-87-6 99.92%
    Formoterol (hemifumarate hydrate) (Standard) is the analytical standard of Formoterol (hemifumarate hydrate). This product is intended for research and analytical applications. Formoterol hemifumarate hydrate is a selective, long-acting beta 2-adrenoceptor agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD). Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury.
    N-Decanoyl-L-homoserine lactone (Standard)
  • HY-143831S
    Cefepime-d8 sulfate 131857-33-5 99.21%
    Cefepime-d8 (BMY-28142-d8) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC50 of 21.115 mM and a Ki of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABAA receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.
    Cefepime-d8 sulfate
  • HY-146535S
    Daptomycin-d5 TFA
    Daptomycin-d5 (LY146032-d5) TFA is the deuterium labeled Daptomycin TFA. Daptomycin TFA is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
    Daptomycin-d5 TFA
  • HY-147266C
    Elebsiran scramble negative control 98.03%
    Elebsiran scramble negative control is the scrambled sequence of Elebsiran (HY-147266), and its modification method is the same. Elebsiran scramble negative control can be used as the negative control for Elebsiran.
    Elebsiran scramble negative control
  • HY-158824A
    Asvasiran sodium 1386946-83-3
    Asvasiran sodium is a siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication.
    Asvasiran sodium
  • HY-159628A
    Glu-AMS TEA 1810728-44-9 98%
    Glu-AMS TEA is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the Ki of 2.8 nM.
    Glu-AMS TEA
  • HY-161752A
    (E)-Antibacterial agent 224 84889-00-9 98%
    (E)-Antibacterial agent 224 is an isomer of Antibacterial agent 224 (HY-161752). Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system.
    (E)-Antibacterial agent 224
  • HY-162959A
    BWC0977 formic 3027162-72-4 99.61%
    BWC0977 formic is an antibacterial agent that inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 formic exhibits a minimum inhibitory concentration (MIC90) of 0.03-2 µg/mL against MDR (Multi-Drug Resistant) Gram-negative bacteria.
    BWC0977 formic
  • HY-166114A
    (Z)-Heptaprenyl-MPDA diammonium 103476-28-4 98%
    (Z)-Heptaprenyl-MPDA ((Z)-Heptaprenyl phosphate) diammonium is the (Z)-isomer of Heptaprenyl-MPDA (HY-166114). Heptaprenyl-MPDA (Heptaprenyl phosphate) is a short-chain homolog of undecaprenyl phosphate, is an endogenous substrate of Phospho-MurNAc-pentapeptide translocase (MraY). Heptaprenyl-MPDA can be used for bacterial infections research.
    (Z)-Heptaprenyl-MPDA diammonium
  • HY-170547A
    DNA polymerase-IN-6 formic
    DNA polymerase-IN-6 formic is an antiviral agent and a DNA polymerase inhibitor. DNA polymerase-IN-6 formic inhibits the replication of HCMV, HSV-1, HSV-2 and EBV. DNA polymerase-IN-6 formic exhibits low cytotoxicity in mammalian cells. DNA polymerase-IN-6 formic can be used in research related to viral infections.
    DNA polymerase-IN-6 formic
  • HY-17395AR
    Terbinafine (Standard) 91161-71-6 99.79%
    Terbinafine (Standard) is the analytical standard of Terbinafine. This product is intended for research and analytical applications. Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Terbinafine (Standard)
  • HY-B0334AR
    Sulbactam sodium (Standard) 69388-84-7 99.41%
    Sulbactam (sodium) (Standard) is the analytical standard of Sulbactam (sodium). This product is intended for research and analytical applications. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
    Sulbactam sodium (Standard)
  • HY-B0356BR
    Ciprofloxacin hydrochloride monohydrate (Standard) 86393-32-0 99.63%
    Ciprofloxacin (hydrochloride monohydrate) (Standard) is the analytical standard of Ciprofloxacin (hydrochloride monohydrate). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin hydrochloride monohydrate (Standard)
  • HY-B0810AR
    Pivmecillinam hydrochloride (Standard) 32887-03-9 99.90%
    Pivmecillinam (hydrochloride) (Standard) is the analytical standard of Pivmecillinam (hydrochloride). This product is intended for research and analytical applications. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
    Pivmecillinam hydrochloride (Standard)
  • HY-B1278BR
    (±)-α-Tocopherol acetate (Standard) 7695-91-2 98.86%
    (±)-α-Tocopherol acetate (Standard) is the analytical standard of (±)-α-Tocopherol acetate. This product is intended for research and analytical applications. (±)-α-Tocopherol acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol acetate is the ester of acetic acid and α-tocopherol. (±)-α-Tocopherol acetate can be used for the research of the susceptibility of farmed fish to infectious diseases.
    (±)-α-Tocopherol acetate (Standard)
  • HY-N0565S1
    Doxycycline-d3 (hyclate) (major)
    Doxycycline-d3 hyclate (major) is the deuterium labeled Doxycycline hyclate (HY-N0565B). Doxycycline hyclate is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline hyclate is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline hyclate also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline hyclate induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline hyclate also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline hyclate has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers.
    Doxycycline-d3 (hyclate) (major)
  • HY-N13150A
    Norvancomycin hydrochloride 198774-23-1
    Norvancomycin hydrochloride is a glycopeptide antibiotic which can be found in Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. Norvancomycin hydrochloride can be used for infection research.
    Norvancomycin hydrochloride
製品番号 製品名 / Synonyms Application Reactivity