Hexamidine diisethionate
Based on 1 Customer Validation
Hexamidine diisethionate is an antimicrobial agent targeting Acanthamoeba protozoa. Hexamidine diisethionate is promising for research of ocular infectious diseases such as Acanthamoeba keratitis.
For research use only. We do not sell to patients.
- Purity : 98.75%
- CAS No.: 659-40-5
- Formula: C24H38N4O10S2
- Molecular Weight:606.71
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 659-40-5
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Appearance Solid
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Molecular Weight 606.71
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Formula C24H38N4O10S2
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Color White to off-white
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SMILES
OCCS(=O)(O)=O.OCCS(=O)(O)=O.N=C(C1=CC=C(OCCCCCCOC2=CC=C(C(N)=N)C=C2)C=C1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 23.33 mg/mL (38.45 mM; Need ultrasonic)
DMSO : 11.67 mg/mL (19.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 1.6482 mL | 8.2412 mL | 16.4823 mL | 41.2058 mL |
| 5 mM | 0.3296 mL | 1.6482 mL | 3.2965 mL | 8.2412 mL | |
| 10 mM | 0.1648 mL | 0.8241 mL | 1.6482 mL | 4.1206 mL | |
| 15 mM | 0.1099 mL | 0.5494 mL | 1.0988 mL | 2.7471 mL | |
| H2O | 20 mM | 0.0824 mL | 0.4121 mL | 0.8241 mL | 2.0603 mL |
| 25 mM | 0.0659 mL | 0.3296 mL | 0.6593 mL | 1.6482 mL | |
| 30 mM | 0.0549 mL | 0.2747 mL | 0.5494 mL | 1.3735 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Hexamidine diisethionate Related Classifications
HY-136081A Related Classifications
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