Cefepime-d8 sulfate
Based on 1 Customer Validation
Cefepime-d8 sulfate (BMY-28142-d8 sulfate) is the deuterated-labeled Cefepime (sulfate) (HY-B0616). Cefepime (BMY-28142) sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC50 of 21.115 mM and a Ki of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABAA receptors. Cefepime sulfate exhibits high affinity for PBPs, inhibits the growth of both Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamases.
For research use only. We do not sell to patients.
- Purity : 99.21%
- CAS No.: 131857-33-5
- Formula: C19H18D8N6O9S3
- Molecular Weight:586.69
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Storage:
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 131857-33-5
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Unlabeled CAS 107648-78-2
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Appearance Solid
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Molecular Weight 586.69
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Formula C19H18D8N6O9S3
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Color Off-white to light yellow
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SMILES
OC(C1=C(C[N+]2(C([2H])([2H])C([2H])([2H])C([2H])([2H])C2([2H])[2H])C)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC)=O)([H])N1C3=O)=O.O=S([O-])(O)=O
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Synonyms
BMY-28142-d8 sulfate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Purity & Documentation
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Data Sheet (291 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cefepime-d8 sulfate Related Classifications
HY-143831S Related Classifications
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Keywords
- Cefepime-d8
- 131857-33-5
- BMY-28142-d8
- Isotope-Labeled Compounds
- Antibiotic
- Bacterial
- GABA Receptor
- Penicillin-binding protein (PBP)
- Gamma-aminobutyric acid Receptor
- γ-Aminobutyric acid Receptor
- nosocomial infections
- blood-brain barrier
- gram-negative bacteria
- pneumonia
- gram-positive bacteria
- complicated urinary tract infections
- GABA_A receptors
- anaerobic Bacteroides species
- TEM plasmid β-lactamase
- hPON1
- Inhibitor
- inhibitor
- inhibit