2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-16943
    Moiramide B 155233-31-1 99.24%
    Moiramide B is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of 6 nM. Moiramide B has antibacterial activity.
    Moiramide B
  • HY-17450
    Aplaviroc 461443-59-4 98%
    Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist, with IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
    Aplaviroc
  • HY-18079
    BILB 1941 494856-61-0 98.60%
    BILB 1941 is a potent and specific nonnucleoside inhibitor of the hepatitis C virus (HCV) RNA polymerase in vitro.
    BILB 1941
  • HY-18716
    Dextrorotation nimorazole phosphate ester 1124347-33-6 98.0%
    Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent.
    Dextrorotation nimorazole phosphate ester
  • HY-19581
    Baquiloprim 102280-35-3 99.66%
    Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria.
    Baquiloprim
  • HY-19727
    FOY 251 free base 71079-08-8 98%
    FOY 251 free base, an anti-proteolytic active metabolite of Camostate (HY-13512), acts as a proteinase inhibitor. FOY 25 free base inhibits SARS-CoV-2 infection in cells assay.
    FOY 251 free base
  • HY-19773
    β-Lactamase-IN-1 1075237-97-6 99.87%
    β-Lactamase-IN-1 is an inhibitor of β-Lactamase extracted from patent WO2016027249A1, page 77. β-Lactamase-IN-1 can be used to prepare of tricyclic nitrogen containing compound. β-Lactamase-IN-1 can be used for the research of neisseria gonorrhea infection.
    β-Lactamase-IN-1
  • HY-19856
    Valnivudine hydrochloride 956483-03-7 ≥98.0%
    FV-100 is a potent, selective and orally active anti-varicella zoster virus agent. FV-100 is a proagent of CF-1743. FV-100 exhibits very low toxicity in vivo.
    Valnivudine hydrochloride
  • HY-19936
    ACHN-975 1410809-36-7 98%
    ACHN-975 is a selective LpxC inhibitor and exhibits a subnanomolar LpxC inhibitory activity. ACHN-975 is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).
    ACHN-975
  • HY-22044
    ICA 3374-88-7 99.92%
    ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 µM.
    ICA
  • HY-43575
    Oseltamivir-acetate 1191921-01-3 ≥98.0%
    Oseltamivir-acetate is an impurity of Oseltamivir. Oseltamivir is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
    Oseltamivir-acetate
  • HY-43806
    Antifungal agent 143 109532-65-2 98.69%
    Antifungal agent 143 is potent antifungal agent which also exihibits antibacterial activity. Antifungal agent 143 inhibits growth of Candida albicans and Aspergillus niger, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pyogenes. Antifungal agent 143 can be used for antimicrobial research.
    Antifungal agent 143
  • HY-44688
    S.pombe lumazine synthase-IN-1 331726-35-3 99.72%
    S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively.
    S.pombe lumazine synthase-IN-1
  • HY-50735
    Fiacitabine 69123-90-6 99.27%
    Fiacitabine (NSC 382097; FIAC; FOAC) is a potent and highly selective anti-herpesvirus agent. Fiacitabine acts as an inhibitor of HSV DNA polymerase, with a Ki of 0.26 μM for HSV-1 and 0.42 μM for HSV-2, respectively. Fiacitabine can be efficiently phosphorylated by thymidine kinase encoded by the virus itself to generate FIACTP, an active triphosphate metabolite. Fiacitabine is applicable to research related to herpesvirus infections.
    Fiacitabine
  • HY-59024
    δ-Carboline 245-08-9 98%
    δ-Carboline is a nitrogen-containing heterocyclic compound, and its derivatives all exhibit anti-cancer and antibacterial activities.
    δ-Carboline
  • HY-77173
    Demethoxyencecalin 19013-07-1
    Demethoxyencecalin is a chromene isolated from Helianthus annuus, has antifungal activities.
    Demethoxyencecalin
  • HY-77652
    Nucleoside-Analog-2 876708-01-9
    Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus (HCV) replication. Nucleoside-Analog-2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Nucleoside-Analog-2
  • HY-A0147
    Grepafloxacin 119914-60-2 98%
    Grepafloxacin (OPC-17116) is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin has high tissue penetration and a promising pharmacodynamic profile.
    Grepafloxacin
  • HY-A0203
    Pentosan Polysulfate 37300-21-3 98%
    Pentosan Polysulfate is an orally bioavailable medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate also displays a potent and selective anti-HIV activity. Pentosan Polysulfatecan be used for the research of interstitial cystitis.
    Pentosan Polysulfate
  • HY-B0343
    Sarafloxacin 98105-99-8 98%
    Sarafloxacin (A-56620) is a fluoroquinolone Antibacterial agent. Sarafloxacin inhibits the growth of Staphylococcus aureus, Enterobacteriaceae, and both aminoglycoside-sensitive and aminoglycoside-resistant strains of Pseudomonas aeruginosa.
    Sarafloxacin
Cat. No. Product Name / Synonyms Application Reactivity