Sarafloxacin
Based on 2 publication(s) in Google Scholar
Sarafloxacin (A-56620) is a fluoroquinolone Antibacterial agent. Sarafloxacin inhibits the growth of Staphylococcus aureus, Enterobacteriaceae, and both aminoglycoside-sensitive and aminoglycoside-resistant strains of Pseudomonas aeruginosa.
For research use only. We do not sell to patients.
- CAS No.: 98105-99-8
- Formula: C20H17F2N3O3
- Molecular Weight:385.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Sarafloxacin
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Biological Activity
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Quinolone |
Sarafloxacin (18 h) inhibits the growth of intestinal E. coli strains (MIC50 = 0.63 μg/mL), B. fragilis strains (MIC50 = 8.2 μg/mL) and Bifidobacterium strains (MIC50 = 7.2 μg/mL) in an in vitro simulated intestinal model[1].
Sarafloxacin (0.5-1 mg/L; 20 h) exhibits activity against staphylococci, including multidrug-resistant *Staphylococcus aureus*[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 98105-99-8
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Appearance Solid
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Molecular Weight 385.36
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Formula C20H17F2N3O3
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SMILES
O=C(C1=CN(C2=CC=C(F)C=C2)C3=C(C=C(F)C(N4CCNCC4)=C3)C1=O)O
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Synonyms
A-56620
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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J Biol Chem
Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice. [Abstract]2022 Feb;298(2):101554. PMID: 34973337 -
Microb Pathog
Antibiotic discovery against Piscirickettsia salmonis using a combined in silico and in vitro approach. [Abstract]2023 Jul:180:106122. PMID: 37094756
Purity & Documentation
References
[1]. McConville ML, et al. Effects of sarafloxacin hydrochloride on human enteric bacteria under simulated human gut conditions. Vet Q. 1995;17(1):1-5. [Content Brief]
[2]. Fernandes CJ, et al. In vitro activity of A-56619 and A-56620 against multi-resistant and routine clinical isolates. Chemotherapy. 1988;34(3):216-228. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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