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  3. S.pombe lumazine synthase-IN-1

S.pombe lumazine synthase-IN-1 

Cat. No.: HY-44688 Purity: 98.02%
Handling Instructions

S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively.

For research use only. We do not sell to patients.

S.pombe lumazine synthase-IN-1 Chemical Structure

S.pombe lumazine synthase-IN-1 Chemical Structure

CAS No. : 331726-35-3

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1  mL in DMSO USD 1001 In-stock
Estimated Time of Arrival: December 31
50 mg USD 910 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1450 In-stock
Estimated Time of Arrival: December 31
500 mg USD 3350 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively[1].

IC50 & Target

Ki: 243 μM (Schizosaccharomyces pombe lumazine synthase); 9.6 μM (Mycobacterium tuberculosis lumazine synthase)[1]

In Vitro

S.pombe lumazine synthase-IN-1 (Compound 21) is a class II compound with OCH3 groups displays slightly better potencies than its counterparts with OH groups[1].

Molecular Weight

319.27

Formula

C₁₄H₁₃N₃O₆

CAS No.

331726-35-3

SMILES

O=C1NC(C([N+]([O-])=O)=C(/C=C/C2=CC=C(OC)C(OC)=C2)N1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (97.88 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1321 mL 15.6607 mL 31.3215 mL
5 mM 0.6264 mL 3.1321 mL 6.2643 mL
10 mM 0.3132 mL 1.5661 mL 3.1321 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

S.pombe lumazine synthase-IN-1BacterialFungalAntibioticS. pombeM. tuberculosislumazinesynthasesInhibitorinhibitorinhibit

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S.pombe lumazine synthase-IN-1
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HY-44688
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