Infection

Related Products

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Infection Related Products (17906)
Antibodies (22)

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-116070

Iodoantipyrine	129-81-7	≥98.0%
Iodoantipyrine (4-Iodoantipyrine) is an iodinated Antipyrine (HY-B0171) with potential antiviral activity. Antipyrine (Phenazone) is an antipyretic and analgesic that also serves as a molecular probe of hepatic oxidative metabolites.

HY-116364

AZT triphosphate	92586-35-1	98%
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate also inhibits the DNA polymerase of HBV. AZT triphosphate activates the mitochondria-mediated apoptosis pathway.

HY-116536

N-3-Oxo-tetradecanoyl-L-homoserine lactone	177158-19-9	99.90%
N-3-Oxo-tetradecanoyl-L-homoserine lactone (oxo-C14-HSL) is a rhizobacterial inducer and can improve basic defense against nematodes.

HY-117005

C450-0730	1036730-46-7
C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxN^I209F was not significant.

HY-117025

Manzamine A	104196-68-1	98.2%
Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC₅₀s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1.

HY-117179

Endosulfan sulfate	1031-07-8	99.94%
Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan.

HY-117721

IHVR-11029	1383152-30-4	99.86%
IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC₅₀ of 0.09 μM.

HY-118211

EcDsbB-IN-9	41933-33-9
EcDsbB-IN-9 (Compound 9) is a potent E. coli DsbB (EcDsbB) inhibitor with an IC₅₀ of 1.7 μM and a K_i of 46 nM.

HY-118224

BPH-715	1059677-23-4	99.62%
BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC₅₀ of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells.

HY-118651

Griseoluteic acid	489-76-9
Griseoluteic acid, a phenazine antibiotic, is originally isolated from S. griseoluteus. Griseoluteic acid is a breakdown product of griseolutein A and B.

HY-118659

Benzalphthalide	575-61-1	98.04%
Benzalphthalide (3-Benzylidenephthalide), a phthalate compound, is an insecticide.

HY-118893

Asukamycin	61116-33-4
Asukamycin, a manumycin-type metabolite, could be isolated from Streptomyces nodosus subsp. asukaensis. Asukamycin is an antibiotic and has antimicrobial activity. Asukamycin inhibits growth of various tumor cell lines.

HY-119172

NSC-60339	70-09-7
NSC-60339, an efflux pump inhibitor and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent.

HY-119480

Megazol	19622-55-0	99.20%
Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC₅₀ of 0.01 μg/mL. Megazol can be used for the research of protozoan infections.

HY-119606

Bacimethrin	3690-12-8	98.11%
Bacimethrin (NSC 66577) is an antibacterial agent and is thiamin biosynthesis antagonist.Bacimethrin inhibits bacterial and yeast growth.

HY-119759

Lipoxamycin	32886-15-0	98%
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM.

HY-119819

Psicofuranine	1874-54-0	98.0%
Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of *P. falciparum* growth.

HY-119956

Biflorin	89701-85-9	99.54%
Biflorin has antimicrobial, antitumor, antiinflammatory and antimutagenic activities. Biflorin is found in the roots of Capraria biflora L.

HY-119974

Caracemide	81424-67-1
Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide is a novel anticancer agent derived from a hydroxamic acid and has demonstrated to produce severe central nervous system (CNS) toxicity.

HY-120696

SR9186	1361414-26-7	98.06%
SR9186 (ML368) is a selective CYP3A4 inhibitor with IC₅₀ values of 9, 4, and 38 nM for Midazolam → 1'-hydroxymidazolam, Testosterone → 6β-hydroxytestosterone, and Vincristine → Vincristine M1, respectively. SR-9186 inhibits the development of hepatic-stage P. falciparum and blocks ivermectin metabolism. SR-9186 can be used in breast cancer research.

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Infection

Infection

Infection Related Products (17906)

Antibodies (22)

Infection Related Products (17906):