1. Metabolic Enzyme/Protease
    Anti-infection
  2. Cytochrome P450
    Parasite
  3. SR9186

SR9186 (Synonyms: ML368)

Cat. No.: HY-120696
Handling Instructions

SR9186 (ML368) is a potent CYP3A4 inhibitor with IC50 s for inhibition of midazolam → 1′hydroxymidazolam, testosterone → 6β-hydroxytestosterone, and vincristine → vincristine M1 of 9, 4, and 38 nM, respectively. SR-9186 inhibits liver-stage development of P. falciparum to block ivermectin metabolism.

For research use only. We do not sell to patients.

SR9186 Chemical Structure

SR9186 Chemical Structure

CAS No. : 1361414-26-7

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Description

SR9186 (ML368) is a potent CYP3A4 inhibitor with IC50 s for inhibition of midazolam → 1′hydroxymidazolam, testosterone → 6β-hydroxytestosterone, and vincristine → vincristine M1 of 9, 4, and 38 nM, respectively. SR-9186 inhibits liver-stage development of P. falciparum to block ivermectin metabolism[1].

Molecular Weight

430.46

Formula

C26H18N6O

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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SR9186
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HY-120696
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